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- THC-O-phosphate abstract "THC-O-phosphate is a water-soluble phosphate ester derivative of THC, which functions as a metabolic prodrug for THC itself. It was invented in 1978 in an attempt to get around the poor water solubility of THC and make it easier to inject for the purposes of animal research into its pharmacology and mechanism of action. The main disadvantage of THC phosphate ester is the slow rate of hydrolysis of the ester link, resulting in delayed onset of action and lower potency than the parent drug. Pharmacologically, it parallels the action of psilocybin as a metabolic prodrug for psilocin.THC phosphate ester is made by reacting THC with phosphoryl chloride using pyridine as a solvent, following by quenching with water to produce THC phosphate ester. In the original research the less active but more stable isomer Δ8THC was used, but the same reaction scheme could be used to make the phosphate ester of the more active isomer Δ9THC.".
- THC-O-phosphate iupacName "O-Phosphoryl-Δ8-tetrahydrocannabinol".
- THC-O-phosphate pubchem "9865413".
- THC-O-phosphate thumbnail D8THCphosphate.svg?width=300.
- THC-O-phosphate wikiPageID "9202889".
- THC-O-phosphate wikiPageLength "2614".
- THC-O-phosphate wikiPageOutDegree "12".
- THC-O-phosphate wikiPageRevisionID "653416100".
- THC-O-phosphate wikiPageWikiLink Category:Cannabinoids.
- THC-O-phosphate wikiPageWikiLink Category:Phosphates.
- THC-O-phosphate wikiPageWikiLink Ester.
- THC-O-phosphate wikiPageWikiLink Isomer.
- THC-O-phosphate wikiPageWikiLink Phosphate.
- THC-O-phosphate wikiPageWikiLink Phosphoryl_chloride.
- THC-O-phosphate wikiPageWikiLink Prodrug.
- THC-O-phosphate wikiPageWikiLink Psilocin.
- THC-O-phosphate wikiPageWikiLink Psilocybin.
- THC-O-phosphate wikiPageWikiLink Pyridine.
- THC-O-phosphate wikiPageWikiLink Solubility.
- THC-O-phosphate wikiPageWikiLink Tetrahydrocannabinol.
- THC-O-phosphate wikiPageWikiLinkText "THC-O-phosphate".
- THC-O-phosphate alt "Skeletal formula of THC-O-phosphate".
- THC-O-phosphate alt "Space-filling model of the THC-O-phosphate molecule".
- THC-O-phosphate c "21".
- THC-O-phosphate chemspiderid "21396139".
- THC-O-phosphate h "31".
- THC-O-phosphate image "THC-O-phosphate 3D spacefill.png".
- THC-O-phosphate inchi "1".
- THC-O-phosphate inchikey "SVDBVZOOOSEJCD-UHFFFAOYAA".
- THC-O-phosphate iupacName "O-Phosphoryl-Δ8-tetrahydrocannabinol".
- THC-O-phosphate molecularWeight "394.45".
- THC-O-phosphate o "5".
- THC-O-phosphate p "1".
- THC-O-phosphate pubchem "9865413".
- THC-O-phosphate smiles "OPOc3cccc2OCC1C\C=CCC1c23".
- THC-O-phosphate stdinchi "1".
- THC-O-phosphate stdinchikey "SVDBVZOOOSEJCD-UHFFFAOYSA-N".
- THC-O-phosphate verifiedrevid "401616331".
- THC-O-phosphate watchedfields "changed".
- THC-O-phosphate wikiPageUsesTemplate Template:Cannabinoid-stub.
- THC-O-phosphate wikiPageUsesTemplate Template:Cannabinoids.
- THC-O-phosphate wikiPageUsesTemplate Template:Chemspidercite.
- THC-O-phosphate wikiPageUsesTemplate Template:Drugbox.
- THC-O-phosphate wikiPageUsesTemplate Template:Stdinchicite.
- THC-O-phosphate subject Category:Cannabinoids.
- THC-O-phosphate subject Category:Phosphates.
- THC-O-phosphate hypernym Derivative.
- THC-O-phosphate type ChemicalSubstance.
- THC-O-phosphate type Drug.
- THC-O-phosphate type Cannabinoid.
- THC-O-phosphate type Chemical.
- THC-O-phosphate type Drug.
- THC-O-phosphate type Oxoanion.
- THC-O-phosphate type ChemicalObject.
- THC-O-phosphate type Thing.
- THC-O-phosphate type Q8386.
- THC-O-phosphate comment "THC-O-phosphate is a water-soluble phosphate ester derivative of THC, which functions as a metabolic prodrug for THC itself. It was invented in 1978 in an attempt to get around the poor water solubility of THC and make it easier to inject for the purposes of animal research into its pharmacology and mechanism of action. The main disadvantage of THC phosphate ester is the slow rate of hydrolysis of the ester link, resulting in delayed onset of action and lower potency than the parent drug.".
- THC-O-phosphate label "THC-O-phosphate".
- THC-O-phosphate sameAs Q7670227.
- THC-O-phosphate sameAs m.02803s7.
- THC-O-phosphate sameAs THC-O-fosfat.
- THC-O-phosphate sameAs THC-O-fosfat.
- THC-O-phosphate sameAs Q7670227.
- THC-O-phosphate wasDerivedFrom THC-O-phosphate?oldid=653416100.
- THC-O-phosphate depiction D8THCphosphate.svg.
- THC-O-phosphate isPrimaryTopicOf THC-O-phosphate.