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Matches in DBpedia 2016-04 for { <http://dbpedia.org/resource/Small_nucleolar_RNA_SNORD115> ?p ?o }

• Small_nucleolar_RNA_SNORD115 abstract "SNORD115 (also known as HBII-52) is a non-coding RNA (ncRNA) molecule known as a small nucleoloar RNA which usually functions in guiding the modification of other non-coding RNAs. This type of modifying RNA is usually located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis. HBII-52 refers to the human gene, whereas RBII-52 is used for the rat gene and MBII-52 is used for naming the mouse gene.HBII-52 belongs to the C/D box class of snoRNAs which contain the conserved sequence motifs known as the C box (UGAUGA) and the D box (CUGA). Most of the members of the box C/D family function in directing site-specific 2'-O-methylation of substrate RNAs.In the human genome, HBII-52 is encoded in a tandemly repeated array with another C/D box snoRNA, HBII-85 (SNORD116), in the Prader-Willi syndrome (PWS) region of chromosome 15. However, a microdeletion in one family of the snoRNA HBII-52 cluster has excluded it from playing a major role in the disease. HBII-52 is found in 47 tandem near identical copies on human chromosome 15q11-13. This locus is maternally imprinted, meaning that only the paternal copy of the locus is transcribed. HBII-52 is exclusively expressed in the brain but is absent in PWS patients. HBII-52 lacks any significant complementarity with ribosomal RNAs, but does have an 18 nucleotide region of conserved complementarity to serotonin 2C receptor mRNA. The serotonin 2C receptor is also expressed in the brain. It has been shown that this snoRNA is likely to bind to a silencing element of exon Vb increasing its inclusion and production of a functional spliceform of the serotonin 2C receptor.The chromosomal locus containing the SNORD115 gene cluster has been duplicated in many individuals with autistic traits. A mouse model engineered to have a duplication of the SNORD115 cluster displays autistic-like behaviour.There is evidence that a truncated form of MBII-52 (SNORD115 found in mouse) regulates the alternative splicing of the protein coding genes DPM2, TAF1, RALGPS1, PBRM1, and CRHR1.".
• Small_nucleolar_RNA_SNORD115 thumbnail RF00105.jpg?width=300.
• Small_nucleolar_RNA_SNORD115 wikiPageID "11421899".
• Small_nucleolar_RNA_SNORD115 wikiPageLength "6872".
• Small_nucleolar_RNA_SNORD115 wikiPageOutDegree "27".
• Small_nucleolar_RNA_SNORD115 wikiPageRevisionID "679411777".
• Small_nucleolar_RNA_SNORD115 wikiPageWikiLink 5-HT2C_receptor.
• Small_nucleolar_RNA_SNORD115 wikiPageWikiLink Autism.
• Small_nucleolar_RNA_SNORD115 wikiPageWikiLink Biomolecular_structure.
• Small_nucleolar_RNA_SNORD115 wikiPageWikiLink Category:Small_nuclear_RNA.
• Small_nucleolar_RNA_SNORD115 wikiPageWikiLink Chromosome_15_(human).
• Small_nucleolar_RNA_SNORD115 wikiPageWikiLink Conserved_sequence.
• Small_nucleolar_RNA_SNORD115 wikiPageWikiLink Corticotropin-releasing_hormone_receptor_1.
• Small_nucleolar_RNA_SNORD115 wikiPageWikiLink DPM2.
• Small_nucleolar_RNA_SNORD115 wikiPageWikiLink Deletion_(genetics).
• Small_nucleolar_RNA_SNORD115 wikiPageWikiLink Eukaryote.
• Small_nucleolar_RNA_SNORD115 wikiPageWikiLink Gene.
• Small_nucleolar_RNA_SNORD115 wikiPageWikiLink Methylation.
• Small_nucleolar_RNA_SNORD115 wikiPageWikiLink Non-coding_RNA.
• Small_nucleolar_RNA_SNORD115 wikiPageWikiLink Nucleolus.
• Small_nucleolar_RNA_SNORD115 wikiPageWikiLink Nucleotide.
• Small_nucleolar_RNA_SNORD115 wikiPageWikiLink PBRM1.
• Small_nucleolar_RNA_SNORD115 wikiPageWikiLink Prader–Willi_syndrome.
• Small_nucleolar_RNA_SNORD115 wikiPageWikiLink RALGPS1.
• Small_nucleolar_RNA_SNORD115 wikiPageWikiLink Ribosomal_RNA.
• Small_nucleolar_RNA_SNORD115 wikiPageWikiLink Small_nuclear_RNA.
• Small_nucleolar_RNA_SNORD115 wikiPageWikiLink Small_nucleolar_RNA.
• Small_nucleolar_RNA_SNORD115 wikiPageWikiLink Small_nucleolar_RNA_SNORD116.
• Small_nucleolar_RNA_SNORD115 wikiPageWikiLink TAF1.
• Small_nucleolar_RNA_SNORD115 wikiPageWikiLinkText "HBII-52".
• Small_nucleolar_RNA_SNORD115 wikiPageWikiLinkText "SNORD115".
• Small_nucleolar_RNA_SNORD115 wikiPageWikiLinkText "Small nucleolar RNA SNORD115".
• Small_nucleolar_RNA_SNORD115 wikiPageWikiLinkText "small nucleolar RNA SNORD115".
• Small_nucleolar_RNA_SNORD115 altsymbols "snoHBII-52; HBII-52".
• Small_nucleolar_RNA_SNORD115 caption "Predicted secondary structure and sequence conservation of SNORD115".
• Small_nucleolar_RNA_SNORD115 id "HBII-52-1".
• Small_nucleolar_RNA_SNORD115 id "RF00105".
• Small_nucleolar_RNA_SNORD115 name "SNORD115".
• Small_nucleolar_RNA_SNORD115 name "Small nucleolar RNA SNORD115".
• Small_nucleolar_RNA_SNORD115 rfam "RF00105".
• Small_nucleolar_RNA_SNORD115 rnaType "Gene; snRNA; snoRNA; CD-box".
• Small_nucleolar_RNA_SNORD115 symbol "SNORD115".
• Small_nucleolar_RNA_SNORD115 taxDomain Eukaryote.
• Small_nucleolar_RNA_SNORD115 wikiPageUsesTemplate Template:GO.
• Small_nucleolar_RNA_SNORD115 wikiPageUsesTemplate Template:Infobox_rfam.
• Small_nucleolar_RNA_SNORD115 wikiPageUsesTemplate Template:Rfam.
• Small_nucleolar_RNA_SNORD115 wikiPageUsesTemplate Template:SO.
• Small_nucleolar_RNA_SNORD115 wikiPageUsesTemplate Template:Small_nucleolar_RNA.
• Small_nucleolar_RNA_SNORD115 wikiPageUsesTemplate Template:SnoRNABase.
• Small_nucleolar_RNA_SNORD115 subject Category:Small_nuclear_RNA.
• Small_nucleolar_RNA_SNORD115 hypernym Molecule.
• Small_nucleolar_RNA_SNORD115 type ChemicalCompound.
• Small_nucleolar_RNA_SNORD115 comment "SNORD115 (also known as HBII-52) is a non-coding RNA (ncRNA) molecule known as a small nucleoloar RNA which usually functions in guiding the modification of other non-coding RNAs. This type of modifying RNA is usually located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis.".
• Small_nucleolar_RNA_SNORD115 label "Small nucleolar RNA SNORD115".
• Small_nucleolar_RNA_SNORD115 sameAs Q17148189.
• Small_nucleolar_RNA_SNORD115 sameAs m.02rc1kv.
• Small_nucleolar_RNA_SNORD115 sameAs Q17148189.
• Small_nucleolar_RNA_SNORD115 wasDerivedFrom Small_nucleolar_RNA_SNORD115?oldid=679411777.
• Small_nucleolar_RNA_SNORD115 depiction RF00105.jpg.
• Small_nucleolar_RNA_SNORD115 isPrimaryTopicOf Small_nucleolar_RNA_SNORD115.