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- Shunting_inhibition abstract "Shunting Inhibition, also known as divisive inhibition, is a form of postsynaptic potential inhibition that can be represented mathematically as reducing the excitatory potential by division, rather than linear subtraction. This form of inhibition is termed \"shunting\" because of the synaptic conductance short-circuit currents that are generated at adjacent excitatory synapses. If a shunting inhibitory synapse is activated, the input resistance is reduced locally and, following Ohm's law, the amplitude of subsequent excitatory postsynaptic potential (EPSP) is reduced. This simple scenario arises if the inhibitory synaptic reversal potential is identical to the resting potential.Shunting inhibition is theorized to be a type of gain control mechanism, regulating the responses of neurons. Simple inhibition such as hyperpolarization has a subtractive effect on the depolarization caused by concurrent excitation, whereas shunting inhibition can in some cases account for a divisive effect.Some evidence exists that shunting inhibition can have a divisive effect on neuronal responses, at least on subthreshold postsynaptic potentials. In a 2005 article, researchers Abbott and Chance state that \"Although the importance of gain modulation and multiplicative interaction in general has been appreciated for many years, it has proven difficult to uncover a realistic biophysical mechanism by which it can occur. It is important to note that, despite comments in the literature to the contrary (see above), divisive inhibition of neuronal responses cannot arise from shunting inhibition. This has been shown theoretically as well as experimentally - inhibition has the same subtractive effect on firing rates whether it is of the shunting or hyperpolarizing variety.\"Thus, shunting inhibition does not provide a plausible mechanism for neuronal gain modulation.".
- Shunting_inhibition wikiPageID "16900389".
- Shunting_inhibition wikiPageLength "3709".
- Shunting_inhibition wikiPageOutDegree "12".
- Shunting_inhibition wikiPageRevisionID "654771746".
- Shunting_inhibition wikiPageWikiLink Category:Neurophysiology.
- Shunting_inhibition wikiPageWikiLink Control_theory.
- Shunting_inhibition wikiPageWikiLink Electrical_resistance_and_conductance.
- Shunting_inhibition wikiPageWikiLink Excitatory_postsynaptic_potential.
- Shunting_inhibition wikiPageWikiLink Excitatory_synapse.
- Shunting_inhibition wikiPageWikiLink Inhibitory_postsynaptic_potential.
- Shunting_inhibition wikiPageWikiLink Input_impedance.
- Shunting_inhibition wikiPageWikiLink Neuron.
- Shunting_inhibition wikiPageWikiLink Ohms_law.
- Shunting_inhibition wikiPageWikiLink Short_circuit.
- Shunting_inhibition wikiPageWikiLink Synapse.
- Shunting_inhibition wikiPageWikiLinkText "Shunting inhibition".
- Shunting_inhibition wikiPageWikiLinkText "shunting inhibition".
- Shunting_inhibition wikiPageWikiLinkText "shunting".
- Shunting_inhibition wikiPageUsesTemplate Template:Reflist.
- Shunting_inhibition wikiPageUsesTemplate Template:Science-stub.
- Shunting_inhibition subject Category:Neurophysiology.
- Shunting_inhibition hypernym Form.
- Shunting_inhibition comment "Shunting Inhibition, also known as divisive inhibition, is a form of postsynaptic potential inhibition that can be represented mathematically as reducing the excitatory potential by division, rather than linear subtraction. This form of inhibition is termed \"shunting\" because of the synaptic conductance short-circuit currents that are generated at adjacent excitatory synapses.".
- Shunting_inhibition label "Shunting inhibition".
- Shunting_inhibition sameAs Q7505166.
- Shunting_inhibition sameAs m.0411mf8.
- Shunting_inhibition sameAs Q7505166.
- Shunting_inhibition wasDerivedFrom Shunting_inhibition?oldid=654771746.
- Shunting_inhibition isPrimaryTopicOf Shunting_inhibition.