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- Schistosomiasis_vaccine abstract "A Schistosomiasis vaccine is a vaccine against Schistosomiasis (also known as bilharzia, bilharziosis or snail fever), a parasitic disease caused by several species of fluke of the genus Schistosoma. No effective vaccine for the disease exists yet. Schistosomiasis affects over 200 million people worldwide, mainly in rural agricultural and peri-urban areas of developing countries, and approximately 10% suffer severe health complications from the infection. While chemotherepeutic drugs, such as praziquantel, oxamniquine and metrifonate, are currently considered safe and effective for the treatment of schistosomiasis, reinfection occurs frequently following drug treatment, thus a vaccine is sought to provide long-term treatment. Additionally, experimental vaccination efforts have been successful in animal models of schistosomiasis.Paramyosin has been proposed as a vaccine candidate.At present Sm-p80 (calpain) is the sole schistosome vaccine candidate that has been tested for its prophylactic and antifecundity efficacy in different vaccine formulations and approaches (e.g., DNA alone, recombinant protein and prime boost) in two very different experimental animal models (mouse and baboon) of infection and disease. Sm-p80-based vaccine formulation(s) have four effects: Reduction in adult worm numbers; Reduction in egg production (complete elimination of egg induced pathology both in baboons and mice); Protection against acute schistosomiasis; Therapeutic effect on adult worms. This vaccine is now ready for human clinical trials.Another target is Sm14.".
- Schistosomiasis_vaccine thumbnail Schistosomiasis_Life_Cycle.png?width=300.
- Schistosomiasis_vaccine wikiPageID "21116598".
- Schistosomiasis_vaccine wikiPageLength "6892".
- Schistosomiasis_vaccine wikiPageOutDegree "20".
- Schistosomiasis_vaccine wikiPageRevisionID "650938287".
- Schistosomiasis_vaccine wikiPageWikiLink Category:Vaccines.
- Schistosomiasis_vaccine wikiPageWikiLink Developing_country.
- Schistosomiasis_vaccine wikiPageWikiLink George_Washington_University.
- Schistosomiasis_vaccine wikiPageWikiLink London_School_of_Hygiene_&_Tropical_Medicine.
- Schistosomiasis_vaccine wikiPageWikiLink Metrifonate.
- Schistosomiasis_vaccine wikiPageWikiLink Model_organism.
- Schistosomiasis_vaccine wikiPageWikiLink National_Institute_of_Parasitic_Diseases.
- Schistosomiasis_vaccine wikiPageWikiLink Neglected_tropical_diseases.
- Schistosomiasis_vaccine wikiPageWikiLink Oswaldo_Cruz_Foundation.
- Schistosomiasis_vaccine wikiPageWikiLink Oxamniquine.
- Schistosomiasis_vaccine wikiPageWikiLink Paramyosin.
- Schistosomiasis_vaccine wikiPageWikiLink Parasitic_disease.
- Schistosomiasis_vaccine wikiPageWikiLink Pharmaceutical_industry.
- Schistosomiasis_vaccine wikiPageWikiLink Praziquantel.
- Schistosomiasis_vaccine wikiPageWikiLink QIMR_Berghofer_Medical_Research_Institute.
- Schistosomiasis_vaccine wikiPageWikiLink Sabin_Vaccine_Institute.
- Schistosomiasis_vaccine wikiPageWikiLink Schistosoma.
- Schistosomiasis_vaccine wikiPageWikiLink Schistosomiasis.
- Schistosomiasis_vaccine wikiPageWikiLink Trematoda.
- Schistosomiasis_vaccine wikiPageWikiLink File:Schistosomiasis_Life_Cycle.png.
- Schistosomiasis_vaccine wikiPageWikiLinkText "Schistosomiasis vaccine".
- Schistosomiasis_vaccine wikiPageWikiLinkText "schistosomiasis vaccine".
- Schistosomiasis_vaccine wikiPageUsesTemplate Template:Citation_needed.
- Schistosomiasis_vaccine wikiPageUsesTemplate Template:ClinicalTrialsGov.
- Schistosomiasis_vaccine wikiPageUsesTemplate Template:Reflist.
- Schistosomiasis_vaccine wikiPageUsesTemplate Template:Vaccines.
- Schistosomiasis_vaccine subject Category:Vaccines.
- Schistosomiasis_vaccine hypernym Vaccine.
- Schistosomiasis_vaccine type Drug.
- Schistosomiasis_vaccine type Drug.
- Schistosomiasis_vaccine comment "A Schistosomiasis vaccine is a vaccine against Schistosomiasis (also known as bilharzia, bilharziosis or snail fever), a parasitic disease caused by several species of fluke of the genus Schistosoma. No effective vaccine for the disease exists yet. Schistosomiasis affects over 200 million people worldwide, mainly in rural agricultural and peri-urban areas of developing countries, and approximately 10% suffer severe health complications from the infection.".
- Schistosomiasis_vaccine label "Schistosomiasis vaccine".
- Schistosomiasis_vaccine sameAs Q7431535.
- Schistosomiasis_vaccine sameAs لقاح_البلهارسيا.
- Schistosomiasis_vaccine sameAs Schistosomiasisimpfstoff.
- Schistosomiasis_vaccine sameAs m.05c006s.
- Schistosomiasis_vaccine sameAs Q7431535.
- Schistosomiasis_vaccine wasDerivedFrom Schistosomiasis_vaccine?oldid=650938287.
- Schistosomiasis_vaccine depiction Schistosomiasis_Life_Cycle.png.
- Schistosomiasis_vaccine isPrimaryTopicOf Schistosomiasis_vaccine.
