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- SF3A1 abstract "Splicing factor 3 subunit 1 is a protein that in humans is encoded by the SF3A1 gene.This gene encodes subunit 1 of the splicing factor 3a protein complex. The splicing factor 3a heterotrimer includes subunits 1, 2 and 3 and is necessary for the in vitro conversion of 15S U2 snRNP into an active 17S particle that performs pre-mRNA splicing. Subunit 1 belongs to the SURP protein family; named for the SURP (also called SWAP or Suppressor-of-White-APricot) motifs that are thought to mediate RNA binding. Subunit 1 has tandemly repeated SURP motifs in its amino-terminal half while its carboxy-terminal half contains a proline-rich region and a ubiquitin-like domain. Binding studies with truncated subunit 1 derivatives demonstrated that the two SURP motifs are necessary for binding to subunit 3 while contacts with subunit 2 may occur through sequences carboxy-terminal to the SURP motifs. Alternative splicing results in multiple transcript variants encoding different isoforms.".
- SF3A1 entrezgene "10291".
- SF3A1 wikiPageID "14760804".
- SF3A1 wikiPageLength "9836".
- SF3A1 wikiPageOutDegree "5".
- SF3A1 wikiPageRevisionID "679038865".
- SF3A1 wikiPageWikiLink CDC5L.
- SF3A1 wikiPageWikiLink Gene.
- SF3A1 wikiPageWikiLink Protein.
- SF3A1 wikiPageWikiLink Protein–protein_interaction.
- SF3A1 wikiPageWikiLink SF3A3.
- SF3A1 wikiPageWikiLinkText "SF3A1".
- SF3A1 requireManualInspection "no".
- SF3A1 summaryText "--05-02".
- SF3A1 updateCitations "yes".
- SF3A1 updatePage "yes".
- SF3A1 updateProteinBox "yes".
- SF3A1 updateSummary "yes".
- SF3A1 wikiPageUsesTemplate Template:Cite_journal.
- SF3A1 wikiPageUsesTemplate Template:Gene-22-stub.
- SF3A1 wikiPageUsesTemplate Template:PBB.
- SF3A1 wikiPageUsesTemplate Template:PBB_Controls.
- SF3A1 wikiPageUsesTemplate Template:PBB_Further_reading.
- SF3A1 wikiPageUsesTemplate Template:PBB_Summary.
- SF3A1 wikiPageUsesTemplate Template:PDB_Gallery.
- SF3A1 wikiPageUsesTemplate Template:Refbegin.
- SF3A1 wikiPageUsesTemplate Template:Refend.
- SF3A1 wikiPageUsesTemplate Template:Reflist.
- SF3A1 wikiPageUsesTemplate Template:UCSC_gene_details.
- SF3A1 wikiPageUsesTemplate Template:UCSC_genome_browser.
- SF3A1 hypernym Protein.
- SF3A1 type Biomolecule.
- SF3A1 type Protein.
- SF3A1 type Thing.
- SF3A1 type Q206229.
- SF3A1 type Q8054.
- SF3A1 comment "Splicing factor 3 subunit 1 is a protein that in humans is encoded by the SF3A1 gene.This gene encodes subunit 1 of the splicing factor 3a protein complex. The splicing factor 3a heterotrimer includes subunits 1, 2 and 3 and is necessary for the in vitro conversion of 15S U2 snRNP into an active 17S particle that performs pre-mRNA splicing.".
- SF3A1 label "SF3A1".
- SF3A1 sameAs Q18035195.
- SF3A1 sameAs m.03gx0vl.
- SF3A1 sameAs Q18035195.
- SF3A1 wasDerivedFrom SF3A1?oldid=679038865.
- SF3A1 isPrimaryTopicOf SF3A1.