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- Ridinilazole abstract "Ridinilazole (SMT19969) is a small molecule antibiotic for oral administration to treat Clostridium difficile infection (CDI).In preclinical studies, ridinilazole showed a potent bactericidal effect against all strains of C. difficile tested.In a Phase 2 proof of concept trial in CDI patients (‘CoDIFy’), ridinilazole showed statistical superiority in sustained clinical response (‘SCR’) rates compared to the standard of care, vancomycin. In this trial, SCR was defined as clinical cure at end of treatment and no recurrence of CDI within 30 days of the end of therapy. SCR rates were 66.7% for ridinilazole compared to 42.4% for vancomycin.Ridinilazole has received Qualified Infectious Disease Product (‘QIDP’) designation and has been granted Fast Track status by the US FDA.".
- Ridinilazole thumbnail Ridinilazole.svg?width=300.
- Ridinilazole wikiPageID "49575625".
- Ridinilazole wikiPageLength "3802".
- Ridinilazole wikiPageOutDegree "11".
- Ridinilazole wikiPageRevisionID "708162476".
- Ridinilazole wikiPageWikiLink Antibiotics.
- Ridinilazole wikiPageWikiLink Category:Antibiotics.
- Ridinilazole wikiPageWikiLink Category:Benzimidazoles.
- Ridinilazole wikiPageWikiLink Category:Pyridines.
- Ridinilazole wikiPageWikiLink Clostridium_difficile_(bacteria).
- Ridinilazole wikiPageWikiLink Clostridium_difficile_colitis.
- Ridinilazole wikiPageWikiLink FDA_Fast_Track_Development_Program.
- Ridinilazole wikiPageWikiLink Food_and_Drug_Administration.
- Ridinilazole wikiPageWikiLink Food_and_Drug_Administration_Safety_and_Innovation_Act.
- Ridinilazole wikiPageWikiLink Small_molecule.
- Ridinilazole wikiPageWikiLink Vancomycin.
- Ridinilazole wikiPageWikiLinkText "Ridinilazole".
- Ridinilazole wikiPageWikiLinkText "ridinilazole".
- Ridinilazole casNumber "308362".
- Ridinilazole chemicalFormula "C24H16N6".
- Ridinilazole chemspiderid "17592423".
- Ridinilazole molecularWeight "388.42".
- Ridinilazole synonyms "SMT19969".
- Ridinilazole wikiPageUsesTemplate Template:Antibiotic-stub.
- Ridinilazole wikiPageUsesTemplate Template:Infobox_drug.
- Ridinilazole wikiPageUsesTemplate Template:Reflist.
- Ridinilazole subject Category:Antibiotics.
- Ridinilazole subject Category:Benzimidazoles.
- Ridinilazole subject Category:Pyridines.
- Ridinilazole hypernym Molecule.
- Ridinilazole type ChemicalCompound.
- Ridinilazole type ChemicalSubstance.
- Ridinilazole type Drug.
- Ridinilazole type ChemicalObject.
- Ridinilazole type Thing.
- Ridinilazole type Q8386.
- Ridinilazole comment "Ridinilazole (SMT19969) is a small molecule antibiotic for oral administration to treat Clostridium difficile infection (CDI).In preclinical studies, ridinilazole showed a potent bactericidal effect against all strains of C. difficile tested.In a Phase 2 proof of concept trial in CDI patients (‘CoDIFy’), ridinilazole showed statistical superiority in sustained clinical response (‘SCR’) rates compared to the standard of care, vancomycin.".
- Ridinilazole label "Ridinilazole".
- Ridinilazole wasDerivedFrom Ridinilazole?oldid=708162476.
- Ridinilazole depiction Ridinilazole.svg.
- Ridinilazole isPrimaryTopicOf Ridinilazole.
