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- Relaxosome abstract "Relaxosome is the complex of proteins that facilitates plasmids during bacterial conjugation. The proteins are encoded by the tra gene in the origin of transfer, oriT, region. The most important of these proteins is relaxase, which is responsible for beginning the conjugation process by cutting at the nic site via transesterification. This nicking results in a DNA-Protein complex with the relaxosome bound to a single strand of the plasmid DNA and an exposed 3' hydroxyl group. Relaxase also unwinds the plasmid being conjugated with its helicase properties. The relaxosome interacts with integration host factors within the oriT.Other genes that code for relaxosome components include TraH, which stabilizes the relaxosome's structural formation, TraI, which encodes for the relaxase protein, TraJ, which recruits the complex to the oriT site, TraK, which increases the 'nicked' state of the target plasmid, and TraY, which imparts single-stranded DNA character on the oriT site. TraM plays a particularly important role in relaxase interaction by stimulating 'relaxed' DNA formation.".
- Relaxosome wikiPageID "13515967".
- Relaxosome wikiPageLength "1774".
- Relaxosome wikiPageOutDegree "11".
- Relaxosome wikiPageRevisionID "679033749".
- Relaxosome wikiPageWikiLink Bacterial_conjugation.
- Relaxosome wikiPageWikiLink Category:Molecular_biology.
- Relaxosome wikiPageWikiLink DNA.
- Relaxosome wikiPageWikiLink Helicase.
- Relaxosome wikiPageWikiLink Multiprotein_complex.
- Relaxosome wikiPageWikiLink OriT.
- Relaxosome wikiPageWikiLink Plasmid.
- Relaxosome wikiPageWikiLink Protein.
- Relaxosome wikiPageWikiLink Relaxase.
- Relaxosome wikiPageWikiLink Tra_gene.
- Relaxosome wikiPageWikiLink Transesterification.
- Relaxosome wikiPageWikiLinkText "relaxosome".
- Relaxosome wikiPageUsesTemplate Template:Bacteria-stub.
- Relaxosome wikiPageUsesTemplate Template:Cite_journal.
- Relaxosome wikiPageUsesTemplate Template:Genetics-stub.
- Relaxosome wikiPageUsesTemplate Template:No_footnotes.
- Relaxosome subject Category:Molecular_biology.
- Relaxosome hypernym Complex.
- Relaxosome type Building.
- Relaxosome comment "Relaxosome is the complex of proteins that facilitates plasmids during bacterial conjugation. The proteins are encoded by the tra gene in the origin of transfer, oriT, region. The most important of these proteins is relaxase, which is responsible for beginning the conjugation process by cutting at the nic site via transesterification. This nicking results in a DNA-Protein complex with the relaxosome bound to a single strand of the plasmid DNA and an exposed 3' hydroxyl group.".
- Relaxosome label "Relaxosome".
- Relaxosome sameAs Q7310886.
- Relaxosome sameAs m.03c7vsz.
- Relaxosome sameAs Релаксосома.
- Relaxosome sameAs Q7310886.
- Relaxosome wasDerivedFrom Relaxosome?oldid=679033749.
- Relaxosome isPrimaryTopicOf Relaxosome.