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- Region_III_of_hippocampus_proper abstract "Region III of hippocampus proper (CA3) is a portion of the hippocampal formation. CA stands for the latin cornus ammonis.Region CA3 receives input along the mossy fibers from granule cells in the dentate gyrus (DG) and from projection cells in entorhinal cortex along the perforant path. The mossy fiber pathway terminates in stratum lucidum while the perforant path passes through stratum lacunosum and terminates in stratum moleculare. The inputs from the medial septum and diagonal band of Broca terminate in stratum radiatum, along with commisural connections from the contralateral hippocampus. The pyramidal cells in CA3 (of which there are approximately 200,000 in each hemisphere in the rat) send some axons back to the hilus, but the majority project to regions CA2 and CA1 (a pathway called the Schaffer collaterals), in addition to a significant number of connections that terminate within CA3 (called recurrent connections). Both the recurrent connections and the Schaffer collaterals terminate preferentially in the septal is dorsal direction from the originating cells. CA3 also sends a small set of output fibers to the lateral septum. The region is conventionally divided into 3 divisions. CA3a is the part of the cell band which is most distal from the dentate (and closest to CA1). CA3b is the middle part of the band nearest to the fimbria/fornix connection. CA3c is the most proximal to the dentate, inserting into the hilus. The region overall has been considered to be the “pacemaker” of the hippocampus. In CA3 much of the synchronous bursting activity associated with interictal epileptiform activity appears to be generated. The excitatory collateral interconnectivity appears to be the property of CA3 most responsible for this. CA3, unlike other regions, has pyramidal cell axon collaterals ramifying extensively with local region and making excitatory contacts with neighbors. CA3 has been implicated in a number of working theories on memory and learning hippocampal processes. Slow oscillatory rhythms (theta-band; 3-8Hz) are cholinergically driven patterns that depend on coupling of interneurons and pyramidal cell axons via gap junctions as well as glutaminergic (excitatory) and GABAergic (inhibitory) synapses. Sharp EEG waves seen here are also implicated in memory consolidation.".
- Region_III_of_hippocampus_proper brainInfoNumber "167".
- Region_III_of_hippocampus_proper brainInfoType "hier".
- Region_III_of_hippocampus_proper grayPage "832".
- Region_III_of_hippocampus_proper graySubject "189".
- Region_III_of_hippocampus_proper thumbnail HippocampalRegions.jpg?width=300.
- Region_III_of_hippocampus_proper wikiPageID "24824388".
- Region_III_of_hippocampus_proper wikiPageLength "3495".
- Region_III_of_hippocampus_proper wikiPageOutDegree "6".
- Region_III_of_hippocampus_proper wikiPageRevisionID "699438049".
- Region_III_of_hippocampus_proper wikiPageWikiLink Anatomical_terms_of_location.
- Region_III_of_hippocampus_proper wikiPageWikiLink Category:Neuroanatomy.
- Region_III_of_hippocampus_proper wikiPageWikiLink Gap_junction.
- Region_III_of_hippocampus_proper wikiPageWikiLink Hippocampal_formation.
- Region_III_of_hippocampus_proper wikiPageWikiLink Hippocampus.
- Region_III_of_hippocampus_proper wikiPageWikiLink Lateral_septum.
- Region_III_of_hippocampus_proper wikiPageWikiLinkText "CA3".
- Region_III_of_hippocampus_proper wikiPageWikiLinkText "Cornu Ammonis 3".
- Region_III_of_hippocampus_proper wikiPageWikiLinkText "Region III of hippocampus proper".
- Region_III_of_hippocampus_proper braininfonumber "167".
- Region_III_of_hippocampus_proper braininfotype "hier".
- Region_III_of_hippocampus_proper caption "Basic circuit of the hippocampus, shown using a modified drawing by Ramon y Cajal. DG: dentate gyrus. Sub: subiculum. EC: entorhinal cortex".
- Region_III_of_hippocampus_proper caption "Diagram of hippocampal regions in a rat brain.".
- Region_III_of_hippocampus_proper graypage "832".
- Region_III_of_hippocampus_proper graysubject "189".
- Region_III_of_hippocampus_proper image "CajalHippocampus .png".
- Region_III_of_hippocampus_proper latin "regio hippocampi proprii III; regio III cornus ammonis; CA3".
- Region_III_of_hippocampus_proper name "Region III of hippocampus proper".
- Region_III_of_hippocampus_proper wikiPageUsesTemplate Template:Infobox_brain.
- Region_III_of_hippocampus_proper wikiPageUsesTemplate Template:Papez_circuit.
- Region_III_of_hippocampus_proper wikiPageUsesTemplate Template:Reflist.
- Region_III_of_hippocampus_proper wikiPageUsesTemplate Template:Rostral_basal_ganglia_and_associated_structures.
- Region_III_of_hippocampus_proper subject Category:Neuroanatomy.
- Region_III_of_hippocampus_proper hypernym Portion.
- Region_III_of_hippocampus_proper type AnatomicalStructure.
- Region_III_of_hippocampus_proper type Brain.
- Region_III_of_hippocampus_proper type Thing.
- Region_III_of_hippocampus_proper type Q4936952.
- Region_III_of_hippocampus_proper comment "Region III of hippocampus proper (CA3) is a portion of the hippocampal formation. CA stands for the latin cornus ammonis.Region CA3 receives input along the mossy fibers from granule cells in the dentate gyrus (DG) and from projection cells in entorhinal cortex along the perforant path. The mossy fiber pathway terminates in stratum lucidum while the perforant path passes through stratum lacunosum and terminates in stratum moleculare.".
- Region_III_of_hippocampus_proper label "Region III of hippocampus proper".
- Region_III_of_hippocampus_proper sameAs Q7308967.
- Region_III_of_hippocampus_proper sameAs m.080ch_d.
- Region_III_of_hippocampus_proper sameAs Q7308967.
- Region_III_of_hippocampus_proper wasDerivedFrom Region_III_of_hippocampus_proper?oldid=699438049.
- Region_III_of_hippocampus_proper depiction HippocampalRegions.jpg.
- Region_III_of_hippocampus_proper isPrimaryTopicOf Region_III_of_hippocampus_proper.
- Region_III_of_hippocampus_proper name "Region III of hippocampus proper".
- Region_III_of_hippocampus_proper name "regio hippocampi proprii III; regio III cornus ammonis; CA3".