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- Protein_ligand abstract "In biochemistry, a protein ligand is an atom, a molecule or an ion which can bind to a specific site (the binding site) on a protein. Alternative names used to mean a protein ligand are affinity reagents or protein binders. To date, antibodies are the most widely used protein ligands in life-science investigations, however, other molecules such as protein scaffolds, nucleic acids, peptides are also being used.Main methods to study protein–ligand interactions are principal hydrodynamic and calorimetric techniques, and principal spectroscopic and structural methods such asFourier transform spectroscopyRaman spectroscopyFluorescence spectroscopyCircular dichroismNuclear magnetic resonanceMass spectrometryAtomic force microscopeParamagnetic probesDual Polarisation InterferometryOther techniques include:fluorescence intensity,bimolecular fluorescence complementation,FRET (fluorescent resonance energy transfer) / FRET quenchingsurface plasmon resonance,Bio-Layer Interferometry,Coimmunopreciptationindirect ELIS,equilibrium dialysis,gel electrophoresis,far western blot,fluorescence polarization anisotropy,electron paramagnetic resonance,Microscale ThermophoresisThe dramatically increased computing power of supercomputers and personal computers has made it possible to study protein–ligand interactions also by means of computational chemistry. For example, a worldwide grid of well over a million ordinary PCs was harnessed for cancer research in the project grid.org, which ended in April 2007. Grid.org has been succeeded by similar projects such as World Community Grid, Human Proteome Folding Project, Compute Against Cancer and Folding@Home.".
- Protein_ligand wikiPageID "1270870".
- Protein_ligand wikiPageLength "2280".
- Protein_ligand wikiPageOutDegree "31".
- Protein_ligand wikiPageRevisionID "552053943".
- Protein_ligand wikiPageWikiLink Antibody.
- Protein_ligand wikiPageWikiLink Atom.
- Protein_ligand wikiPageWikiLink Atomic-force_microscopy.
- Protein_ligand wikiPageWikiLink Binding_site.
- Protein_ligand wikiPageWikiLink Bio-layer_interferometry.
- Protein_ligand wikiPageWikiLink Biochemistry.
- Protein_ligand wikiPageWikiLink Category:Biomolecules.
- Protein_ligand wikiPageWikiLink Category:Chemical_bonding.
- Protein_ligand wikiPageWikiLink Category:Proteins.
- Protein_ligand wikiPageWikiLink Circular_dichroism.
- Protein_ligand wikiPageWikiLink Computational_chemistry.
- Protein_ligand wikiPageWikiLink Compute_Against_Cancer.
- Protein_ligand wikiPageWikiLink Dual-polarization_interferometry.
- Protein_ligand wikiPageWikiLink Fluorescence_spectroscopy.
- Protein_ligand wikiPageWikiLink Folding@home.
- Protein_ligand wikiPageWikiLink Fourier_transform_spectroscopy.
- Protein_ligand wikiPageWikiLink Grid.org.
- Protein_ligand wikiPageWikiLink Human_Proteome_Folding_Project.
- Protein_ligand wikiPageWikiLink Ion.
- Protein_ligand wikiPageWikiLink Ligand.
- Protein_ligand wikiPageWikiLink Mass_spectrometry.
- Protein_ligand wikiPageWikiLink Microscale_thermophoresis.
- Protein_ligand wikiPageWikiLink Molecule.
- Protein_ligand wikiPageWikiLink Nuclear_magnetic_resonance.
- Protein_ligand wikiPageWikiLink Nucleic_acid.
- Protein_ligand wikiPageWikiLink Paramagnetism.
- Protein_ligand wikiPageWikiLink Peptide.
- Protein_ligand wikiPageWikiLink Protein.
- Protein_ligand wikiPageWikiLink Raman_spectroscopy.
- Protein_ligand wikiPageWikiLink Scaffold_protein.
- Protein_ligand wikiPageWikiLink World_Community_Grid.
- Protein_ligand wikiPageWikiLinkText "Protein ligand".
- Protein_ligand wikiPageWikiLinkText "protein ligand".
- Protein_ligand wikiPageWikiLinkText "protein-ligand binding".
- Protein_ligand wikiPageUsesTemplate Template:Merge.
- Protein_ligand subject Category:Biomolecules.
- Protein_ligand subject Category:Chemical_bonding.
- Protein_ligand subject Category:Proteins.
- Protein_ligand hypernym Atom.
- Protein_ligand type Biomolecule.
- Protein_ligand type ComicsCharacter.
- Protein_ligand type Biomolecule.
- Protein_ligand type Nutrient.
- Protein_ligand type Product.
- Protein_ligand comment "In biochemistry, a protein ligand is an atom, a molecule or an ion which can bind to a specific site (the binding site) on a protein. Alternative names used to mean a protein ligand are affinity reagents or protein binders.".
- Protein_ligand label "Protein ligand".
- Protein_ligand sameAs Q7251485.
- Protein_ligand sameAs m.04nytz.
- Protein_ligand sameAs Q7251485.
- Protein_ligand wasDerivedFrom Protein_ligand?oldid=552053943.
- Protein_ligand isPrimaryTopicOf Protein_ligand.