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- Protein_function_prediction abstract "Protein function prediction methods are techniques that bioinformatics researchers use to assign biological or biochemical roles to proteins. These proteins are usually ones that poorly studied or predicted based on genomic sequence data. These predictions are often driven by data-intensive computational procedures. Information may come from nucleic acid sequence homology, gene expression profiles, protein domain structures, text mining of publications, phylogenetic profiles, phenotypic profiles, and protein-protein interaction. Protein function is a broad term: the roles of proteins range from catalysis of biochemical reactions to transport to signal transduction, and a single protein may play a role in multiple processes or cellular pathways.Generally, function can be thought of as, \"anything that happens to or through a protein\". The Gene Ontology Consortium provides a useful classification of functions, based on a dictionary of well-defined terms divided into three main categories of molecular function, biological process and cellular component. Researchers can query this database with a protein name or accession number to retrieve associated Gene Ontology (GO) terms or annotations based on computational or experimental evidence.While techniques such as microarray analysis, RNA interference, and the yeast two-hybrid system can be used to experimentally demonstrate the function of a protein, advances in sequencing technologies have made the rate at which proteins can be experimentally characterized much slower than the rate at which new sequences become available.Thus, the annotation of new sequences is mostly by prediction through computational methods, as these types of annotation can often be done quickly and for many genes or proteins at once. The first such methods inferred function based on homologous proteins with known functions (homology-based function prediction). The development of context-based and structure based methods have expanded what information can be predicted, and a combination of methods can now be used to get a picture of complete cellular pathways based on sequence data. The importance and prevalence of computational prediction of gene function is underlined by an analysis of 'evidence codes' used by the GO database: as of 2010, 98% of annotations were listed under the code IEA (inferred from electronic annotation) while only 0.6% were based on experimental evidence.".
- Protein_function_prediction thumbnail Protein_alignment.jpg?width=300.
- Protein_function_prediction wikiPageExternalLink Blast.cgi.
- Protein_function_prediction wikiPageExternalLink pfam.sanger.ac.uk.
- Protein_function_prediction wikiPageExternalLink prosite.expasy.org.
- Protein_function_prediction wikiPageExternalLink SignalP.
- Protein_function_prediction wikiPageExternalLink CSA.
- Protein_function_prediction wikiPageExternalLink www.genemania.org.
- Protein_function_prediction wikiPageExternalLink www.geneontology.org.
- Protein_function_prediction wikiPageExternalLink home.do.
- Protein_function_prediction wikiPageExternalLink raptorx.uchicago.edu.
- Protein_function_prediction wikiPageExternalLink pixie.
- Protein_function_prediction wikiPageExternalLink dcpredictormain.cgi.
- Protein_function_prediction wikiPageExternalLink dcGO.
- Protein_function_prediction wikiPageExternalLink www.blast2go.com.
- Protein_function_prediction wikiPageID "29467449".
- Protein_function_prediction wikiPageLength "29909".
- Protein_function_prediction wikiPageOutDegree "52".
- Protein_function_prediction wikiPageRevisionID "704255651".
- Protein_function_prediction wikiPageWikiLink Accession_number_(bioinformatics).
- Protein_function_prediction wikiPageWikiLink Active_site.
- Protein_function_prediction wikiPageWikiLink Algorithm.
- Protein_function_prediction wikiPageWikiLink Amino_acid.
- Protein_function_prediction wikiPageWikiLink Bioinformatics.
- Protein_function_prediction wikiPageWikiLink Blast2GO.
- Protein_function_prediction wikiPageWikiLink Category:Bioinformatics.
- Protein_function_prediction wikiPageWikiLink Category:Protein_methods.
- Protein_function_prediction wikiPageWikiLink DcGO.
- Protein_function_prediction wikiPageWikiLink Escherichia_coli.
- Protein_function_prediction wikiPageWikiLink Ethanol.
- Protein_function_prediction wikiPageWikiLink Eukaryote.
- Protein_function_prediction wikiPageWikiLink Functional_genomics.
- Protein_function_prediction wikiPageWikiLink Fusion_gene.
- Protein_function_prediction wikiPageWikiLink Galactokinase.
- Protein_function_prediction wikiPageWikiLink Gene_expression.
- Protein_function_prediction wikiPageWikiLink Gene_ontology.
- Protein_function_prediction wikiPageWikiLink Gene_prediction.
- Protein_function_prediction wikiPageWikiLink Homology_(biology).
- Protein_function_prediction wikiPageWikiLink Homology_modeling.
- Protein_function_prediction wikiPageWikiLink Isopropyl_alcohol.
- Protein_function_prediction wikiPageWikiLink Microarray.
- Protein_function_prediction wikiPageWikiLink Operon.
- Protein_function_prediction wikiPageWikiLink PROSITE.
- Protein_function_prediction wikiPageWikiLink Pfam.
- Protein_function_prediction wikiPageWikiLink Prokaryote.
- Protein_function_prediction wikiPageWikiLink Protein.
- Protein_function_prediction wikiPageWikiLink Protein_Data_Bank.
- Protein_function_prediction wikiPageWikiLink Protein_domain.
- Protein_function_prediction wikiPageWikiLink Protein_structure.
- Protein_function_prediction wikiPageWikiLink Protein_tertiary_structure.
- Protein_function_prediction wikiPageWikiLink _software_for_protein_modeling_and_analysis.
- Protein_function_prediction wikiPageWikiLink Sequence_alignment.
- Protein_function_prediction wikiPageWikiLink Serine.
- Protein_function_prediction wikiPageWikiLink Signal_transduction.
- Protein_function_prediction wikiPageWikiLink Structural_genomics.
- Protein_function_prediction wikiPageWikiLink Subcellular_localization.
- Protein_function_prediction wikiPageWikiLink Text_mining.
- Protein_function_prediction wikiPageWikiLink Threonine.
- Protein_function_prediction wikiPageWikiLink Two-hybrid_screening.
- Protein_function_prediction wikiPageWikiLink Vertex_(graph_theory).
- Protein_function_prediction wikiPageWikiLink X-ray_crystallography.
- Protein_function_prediction wikiPageWikiLink File:Alignment_Abrin_Ricin.png.
- Protein_function_prediction wikiPageWikiLink File:Computational_solvent_mapping_of_AMA1_using_FTMAP.TIF.
- Protein_function_prediction wikiPageWikiLink File:Protein_alignment.jpg.
- Protein_function_prediction wikiPageWikiLink File:STRING_network_image.png.
- Protein_function_prediction wikiPageWikiLinkText "Protein function prediction".
- Protein_function_prediction wikiPageWikiLinkText "functional annotation".
- Protein_function_prediction wikiPageWikiLinkText "predicting protein function".
- Protein_function_prediction wikiPageWikiLinkText "protein function prediction".
- Protein_function_prediction wikiPageWikiLinkText "the function".
- Protein_function_prediction wikiPageUsesTemplate Template:Reflist.
- Protein_function_prediction subject Category:Bioinformatics.
- Protein_function_prediction subject Category:Protein_methods.
- Protein_function_prediction hypernym Techniques.
- Protein_function_prediction type Disease.
- Protein_function_prediction type Weapon.
- Protein_function_prediction type Biostatistic.
- Protein_function_prediction comment "Protein function prediction methods are techniques that bioinformatics researchers use to assign biological or biochemical roles to proteins. These proteins are usually ones that poorly studied or predicted based on genomic sequence data. These predictions are often driven by data-intensive computational procedures.".
- Protein_function_prediction label "Protein function prediction".
- Protein_function_prediction sameAs Q7251473.
- Protein_function_prediction sameAs m.0ds6hqy.
- Protein_function_prediction sameAs Q7251473.
- Protein_function_prediction wasDerivedFrom Protein_function_prediction?oldid=704255651.
- Protein_function_prediction depiction Protein_alignment.jpg.
- Protein_function_prediction isPrimaryTopicOf Protein_function_prediction.