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- Prostvac abstract "PROSTVAC (rilimogene galvacirepvec/rilimogene glafolivec) is a cancer immunotherapy candidate in clinical development by Bavarian Nordic for the treatment of metastatic castration-resistant prostate cancer (mCRPC). PROSTVAC is designed to enable the immune system to recognize and attack prostate cancer cells by triggering a specific and targeted T cell immune response to cancer cells that express the tumor-associated antigen prostate-specific antigen (PSA).PROSTVAC utilizes recombinant poxviruses to express PSA, along with 3 immune-enhancing costimulatory molecules collectively designated as TRICOM (LFA-3, ICAM-1, and B7.1). Treatment is initiated by subcutaneous administration of a priming dose of vaccinia encoding PSA-TRICOM, followed by 6 subsequent boosting doses of fowlpox encoding the same PSA-TRICOM cassette. Using this heterologous prime-boost dosing regimen, the immune system becomes focused on inducing PSA-specific T cell responses, designed to kill tumor cells expressing PSA.".
- Prostvac wikiPageID "44285932".
- Prostvac wikiPageLength "5382".
- Prostvac wikiPageOutDegree "10".
- Prostvac wikiPageRevisionID "691442382".
- Prostvac wikiPageWikiLink Bavarian_Nordic.
- Prostvac wikiPageWikiLink Cancer_immunotherapy.
- Prostvac wikiPageWikiLink Category:Cancer_vaccines.
- Prostvac wikiPageWikiLink Category:Prostate_cancer.
- Prostvac wikiPageWikiLink National_Cancer_Institute.
- Prostvac wikiPageWikiLink Poxviridae.
- Prostvac wikiPageWikiLink Prostate-specific_antigen.
- Prostvac wikiPageWikiLink Prostate_cancer.
- Prostvac wikiPageWikiLink Subcutaneous_injection.
- Prostvac wikiPageWikiLinkText "Prostvac".
- Prostvac chemspiderid "none".
- Prostvac pubchemsubstance "534055".
- Prostvac routesOfAdministration Subcutaneous_injection.
- Prostvac target Prostate_cancer.
- Prostvac type "vaccine".
- Prostvac wikiPageUsesTemplate Template:Drugbox.
- Prostvac wikiPageUsesTemplate Template:Vaccine-stub.
- Prostvac subject Category:Cancer_vaccines.
- Prostvac subject Category:Prostate_cancer.
- Prostvac hypernym Candidate.
- Prostvac type ChemicalSubstance.
- Prostvac type Drug.
- Prostvac type Person.
- Prostvac type ChemicalObject.
- Prostvac type Thing.
- Prostvac type Q8386.
- Prostvac comment "PROSTVAC (rilimogene galvacirepvec/rilimogene glafolivec) is a cancer immunotherapy candidate in clinical development by Bavarian Nordic for the treatment of metastatic castration-resistant prostate cancer (mCRPC).".
- Prostvac label "Prostvac".
- Prostvac sameAs m.0127xx16.
- Prostvac wasDerivedFrom Prostvac?oldid=691442382.
- Prostvac isPrimaryTopicOf Prostvac.