Matches in DBpedia 2016-04 for { <http://dbpedia.org/resource/Pimavanserin> ?p ?o }
- Pimavanserin abstract "Pimavanserin (ACP-103), marketed under the trade name Nuplazid, is a drug developed by Acadia Pharmaceuticals which acts as an inverse agonist on the serotonin receptor subtype 5-HT2A, with 40x selectivity over 5-HT2C, and no significant affinity or activity at 5-HT2B or dopamine receptors. Pimavanserin has met expectations for Phase III clinical trials for the treatment of Parkinson's disease psychosis, and has completed Phase II trials for adjunctive treatment of schizophrenia alongside an antipsychotic medication. It is expected to improve the effectiveness and side effect profile of antipsychotics. The results of a clinical trial examining the efficacy, tolerability and safety of adjunctive pimavanserin to risperidone and haloperidol were published in November 2012 and the results showed that pimavanserin potentiated the antipsychotic effects of subtherapeutic doses of risperidone and improve the tolerability of haloperidol treatment by reducing the incidence of extrapyramidal symptoms.On September 2, 2014, the United States Food and Drug administration granted Breakthrough Therapy status to Acadia's New Drug Application for pimavanserin.".
- Pimavanserin atcPrefix "none".
- Pimavanserin casNumber "706779-91-1".
- Pimavanserin casSupplemental "706782-28-7 (tartrate)".
- Pimavanserin fdaUniiCode "JZ963P0DIK".
- Pimavanserin iupacName "N-(4-fluorophenylmethyl)-N-(1-methylpiperidin-4-yl)-N'-(4-(2-methylpropyloxy)phenylmethyl)carbamide".
- Pimavanserin pubchem "10071196".
- Pimavanserin thumbnail Pimavanserin2DACS2.svg?width=300.
- Pimavanserin wikiPageID "22262723".
- Pimavanserin wikiPageLength "6510".
- Pimavanserin wikiPageOutDegree "21".
- Pimavanserin wikiPageRevisionID "706659198".
- Pimavanserin wikiPageWikiLink 5-HT2A_receptor.
- Pimavanserin wikiPageWikiLink 5-HT2B_receptor.
- Pimavanserin wikiPageWikiLink 5-HT2C_receptor.
- Pimavanserin wikiPageWikiLink 5-HT_receptor.
- Pimavanserin wikiPageWikiLink Acadia_Pharmaceuticals.
- Pimavanserin wikiPageWikiLink Antipsychotic.
- Pimavanserin wikiPageWikiLink Category:Antipsychotics.
- Pimavanserin wikiPageWikiLink Category:Organofluorides.
- Pimavanserin wikiPageWikiLink Category:Phenol_ethers.
- Pimavanserin wikiPageWikiLink Category:Piperidines.
- Pimavanserin wikiPageWikiLink Category:Serotonin_antagonists.
- Pimavanserin wikiPageWikiLink Category:Ureas.
- Pimavanserin wikiPageWikiLink Dopamine_receptor.
- Pimavanserin wikiPageWikiLink Drug.
- Pimavanserin wikiPageWikiLink Extrapyramidal_symptoms.
- Pimavanserin wikiPageWikiLink Inverse_agonist.
- Pimavanserin wikiPageWikiLink Parkinsons_disease.
- Pimavanserin wikiPageWikiLink Psychosis.
- Pimavanserin wikiPageWikiLink Risperidone.
- Pimavanserin wikiPageWikiLink Schizophrenia.
- Pimavanserin wikiPageWikiLink Tartrate.
- Pimavanserin wikiPageWikiLinkText "Pimavanserin (ACP-103)".
- Pimavanserin wikiPageWikiLinkText "Pimavanserin".
- Pimavanserin wikiPageWikiLinkText "pimavanserin".
- Pimavanserin atcPrefix "none".
- Pimavanserin c "25".
- Pimavanserin casNumber "706779".
- Pimavanserin casSupplemental "706782".
- Pimavanserin chemspiderid "8246736".
- Pimavanserin eliminationHalfLife "-201600.0".
- Pimavanserin f "1".
- Pimavanserin h "34".
- Pimavanserin inchi "1".
- Pimavanserin inchikey "RKEWSXXUOLRFBX-UHFFFAOYAB".
- Pimavanserin iupacName "N--N--N'-carbamide".
- Pimavanserin molecularWeight "427.553".
- Pimavanserin n "3".
- Pimavanserin o "2".
- Pimavanserin proteinBound "94".
- Pimavanserin pubchem "10071196".
- Pimavanserin routesOfAdministration "Oral".
- Pimavanserin smiles "CCCOc3cccCNCNCcccc1F".
- Pimavanserin stdinchi "1".
- Pimavanserin stdinchikey "RKEWSXXUOLRFBX-UHFFFAOYSA-N".
- Pimavanserin unii "JZ963P0DIK".
- Pimavanserin verifiedfields "changed".
- Pimavanserin verifiedrevid "448227829".
- Pimavanserin width "200".
- Pimavanserin wikiPageUsesTemplate Template:Antipsychotics.
- Pimavanserin wikiPageUsesTemplate Template:Cascite.
- Pimavanserin wikiPageUsesTemplate Template:Chemspidercite.
- Pimavanserin wikiPageUsesTemplate Template:Drugbox.
- Pimavanserin wikiPageUsesTemplate Template:Fdacite.
- Pimavanserin wikiPageUsesTemplate Template:Nervous-system-drug-stub.
- Pimavanserin wikiPageUsesTemplate Template:Reflist.
- Pimavanserin wikiPageUsesTemplate Template:Serotonergics.
- Pimavanserin wikiPageUsesTemplate Template:Stdinchicite.
- Pimavanserin subject Category:Antipsychotics.
- Pimavanserin subject Category:Organofluorides.
- Pimavanserin subject Category:Phenol_ethers.
- Pimavanserin subject Category:Piperidines.
- Pimavanserin subject Category:Serotonin_antagonists.
- Pimavanserin subject Category:Ureas.
- Pimavanserin hypernym Drug.
- Pimavanserin type ChemicalSubstance.
- Pimavanserin type Drug.
- Pimavanserin type Amide.
- Pimavanserin type Antagonist.
- Pimavanserin type Chemical.
- Pimavanserin type Drug.
- Pimavanserin type Ether.
- Pimavanserin type Heterocycle.
- Pimavanserin type Organofluoride.
- Pimavanserin type Organohalide.
- Pimavanserin type Organofluoride.
- Pimavanserin type Organohalide.
- Pimavanserin type ChemicalObject.
- Pimavanserin type Thing.
- Pimavanserin type Q8386.
- Pimavanserin comment "Pimavanserin (ACP-103), marketed under the trade name Nuplazid, is a drug developed by Acadia Pharmaceuticals which acts as an inverse agonist on the serotonin receptor subtype 5-HT2A, with 40x selectivity over 5-HT2C, and no significant affinity or activity at 5-HT2B or dopamine receptors.".
- Pimavanserin label "Pimavanserin".
- Pimavanserin sameAs Q7194603.
- Pimavanserin sameAs Pimavansérine.
- Pimavanserin sameAs Pimawanseryna.
- Pimavanserin sameAs m.05q7bl_.
- Pimavanserin sameAs Pimavanserin.
- Pimavanserin sameAs Pimavanserin.
- Pimavanserin sameAs Q7194603.