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- Perifosine abstract "Perifosine (also KRX-0401) is a drug candidate being developed for a variety of cancer indications.It is an alkyl-phospholipid structurally related to miltefosine. It acts as an Akt inhibitor and a PI3K inhibitor.It was being developed by Keryx Biopharmaceuticals who have licensed it from Æterna Zentaris Inc.In 2010 perifosine has reached phase II. In one phase II trial for metastatic colon cancer perifosine doubled time to progression.It has orphan drug status in the U.S. for the treatment of multiple myeloma and neuroblastoma, and for multiple myeloma in the EU.In 2011 it was in a phase III trial for colorectal cancer, and another for multiple myeloma. On April 2, 2012, it was announced that perifosine failed its phase III clinical trial for treatment of colon cancer. Detailed results were released in June 2012. On March 11, 2013 Aeterna Zentaris announced the discontinuing of Phase 3 clinical trial of perifosine for the treatment of relapsed and refractory multiple myeloma http://www.aezsinc.com/en/page.php?p=60&q=550.".
- Perifosine iupacName "1,1-Dimethylpiperidinium-4-yl octadecyl phosphate".
- Perifosine thumbnail Perifosine.svg?width=300.
- Perifosine wikiPageExternalLink page.php?p=60&q=550..
- Perifosine wikiPageID "31032459".
- Perifosine wikiPageLength "4400".
- Perifosine wikiPageOutDegree "16".
- Perifosine wikiPageRevisionID "688128069".
- Perifosine wikiPageWikiLink Category:Organophosphates.
- Perifosine wikiPageWikiLink Category:Phosphoinositide_3-kinase_inhibitors.
- Perifosine wikiPageWikiLink Category:Phospholipids.
- Perifosine wikiPageWikiLink Category:Quaternary_ammonium_compounds.
- Perifosine wikiPageWikiLink Category:Zwitterions.
- Perifosine wikiPageWikiLink Colorectal_cancer.
- Perifosine wikiPageWikiLink Miltefosine.
- Perifosine wikiPageWikiLink Multiple_myeloma.
- Perifosine wikiPageWikiLink Neuroblastoma.
- Perifosine wikiPageWikiLink Orphan_drug.
- Perifosine wikiPageWikiLink Phosphoinositide_3-kinase_inhibitor.
- Perifosine wikiPageWikiLink Phospholipid.
- Perifosine wikiPageWikiLink Progression-free_survival.
- Perifosine wikiPageWikiLink Protein_kinase_B.
- Perifosine wikiPageWikiLink Æterna_Zentaris.
- Perifosine wikiPageWikiLinkText "Perifosine".
- Perifosine wikiPageWikiLinkText "perifosine".
- Perifosine imagealt "Skeletal formula of perifosine".
- Perifosine imagealt "Space-filling model of the perifosine zwitterion".
- Perifosine imagefile "Perifosine-zwitterion-3D-spacefill.png".
- Perifosine imagefile "Perifosine.svg".
- Perifosine imagesize "300".
- Perifosine imagesize "320".
- Perifosine iupacname "11".
- Perifosine othernames "D 21266; KRX 0401".
- Perifosine wikiPageUsesTemplate Template:Antineoplastic-drug-stub.
- Perifosine wikiPageUsesTemplate Template:Cascite.
- Perifosine wikiPageUsesTemplate Template:Chembox.
- Perifosine wikiPageUsesTemplate Template:Chembox_Hazards.
- Perifosine wikiPageUsesTemplate Template:Chembox_Identifiers.
- Perifosine wikiPageUsesTemplate Template:Chembox_Pharmacology.
- Perifosine wikiPageUsesTemplate Template:Chembox_Properties.
- Perifosine wikiPageUsesTemplate Template:Fdacite.
- Perifosine wikiPageUsesTemplate Template:Reflist.
- Perifosine subject Category:Organophosphates.
- Perifosine subject Category:Phosphoinositide_3-kinase_inhibitors.
- Perifosine subject Category:Phospholipids.
- Perifosine subject Category:Quaternary_ammonium_compounds.
- Perifosine subject Category:Zwitterions.
- Perifosine hypernym Candidate.
- Perifosine type ChemicalCompound.
- Perifosine type ChemicalSubstance.
- Perifosine type Person.
- Perifosine type Ester.
- Perifosine type Inhibitor.
- Perifosine type Organophosphate.
- Perifosine type Organophosphoru.
- Perifosine type Organophosphate.
- Perifosine type Organophosphoru.
- Perifosine type ChemicalObject.
- Perifosine type Thing.
- Perifosine type Q11173.
- Perifosine comment "Perifosine (also KRX-0401) is a drug candidate being developed for a variety of cancer indications.It is an alkyl-phospholipid structurally related to miltefosine. It acts as an Akt inhibitor and a PI3K inhibitor.It was being developed by Keryx Biopharmaceuticals who have licensed it from Æterna Zentaris Inc.In 2010 perifosine has reached phase II. In one phase II trial for metastatic colon cancer perifosine doubled time to progression.It has orphan drug status in the U.S.".
- Perifosine label "Perifosine".
- Perifosine sameAs Q3411917.
- Perifosine sameAs پریفوسین.
- Perifosine sameAs Périfosine.
- Perifosine sameAs m.0gg9fv_.
- Perifosine sameAs Perifozin.
- Perifosine sameAs Perifozin.
- Perifosine sameAs Q3411917.
- Perifosine wasDerivedFrom Perifosine?oldid=688128069.
- Perifosine depiction Perifosine.svg.
- Perifosine isPrimaryTopicOf Perifosine.