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- Parthanatos abstract "Parthanatos (derived from the Greek Θάνατος, “Death”) is a form of programmed cell death that is distinct from other cell death processes such as necrosis and apoptosis. While necrosis is caused by acute cell injury resulting in traumatic cell death and apoptosis is a highly controlled process signalled by apoptotic intracellular signals, parthanatos is caused by the accumulation of PAR and the nuclear translocation of apoptosis-inducing factor (AIF) from mitochondria. Parthanatos is also known as PARP-1 dependent cell death. PARP-1 mediates parthanatos when it is over-activated in response to extreme genomic stress and synthesizes PAR which causes nuclear translocation of AIF. Parthanatos is involved in diseases that afflict hundreds of millions of people worldwide. Well known diseases involving parthanatos include Parkinson’s disease, stroke, heart attack, and diabetes. It also has potential use as a treatment for ameliorating disease and various medical conditions such as diabetes and obesity.".
- Parthanatos wikiPageID "48712402".
- Parthanatos wikiPageLength "20706".
- Parthanatos wikiPageOutDegree "98".
- Parthanatos wikiPageRevisionID "705295418".
- Parthanatos wikiPageWikiLink Active_site.
- Parthanatos wikiPageWikiLink Adenosine_diphosphate_ribose.
- Parthanatos wikiPageWikiLink Alkali.
- Parthanatos wikiPageWikiLink Apoptosis.
- Parthanatos wikiPageWikiLink Apoptosis-inducing_factor.
- Parthanatos wikiPageWikiLink Arthritis.
- Parthanatos wikiPageWikiLink BRCA1.
- Parthanatos wikiPageWikiLink Base_excision_repair.
- Parthanatos wikiPageWikiLink Cancer.
- Parthanatos wikiPageWikiLink Caspase.
- Parthanatos wikiPageWikiLink Catalysis.
- Parthanatos wikiPageWikiLink Category:Cellular_processes.
- Parthanatos wikiPageWikiLink Category:Medical_aspects_of_death.
- Parthanatos wikiPageWikiLink Cell_death.
- Parthanatos wikiPageWikiLink Cell_nucleus.
- Parthanatos wikiPageWikiLink Cell_signaling.
- Parthanatos wikiPageWikiLink Chromatin.
- Parthanatos wikiPageWikiLink Colitis.
- Parthanatos wikiPageWikiLink Covalent_bond.
- Parthanatos wikiPageWikiLink Cytochrome_c.
- Parthanatos wikiPageWikiLink Cytosol.
- Parthanatos wikiPageWikiLink DNA.
- Parthanatos wikiPageWikiLink DNA-binding_domain.
- Parthanatos wikiPageWikiLink DNA_repair.
- Parthanatos wikiPageWikiLink Death.
- Parthanatos wikiPageWikiLink Desmethylprodine.
- Parthanatos wikiPageWikiLink Diabetes_mellitus.
- Parthanatos wikiPageWikiLink Dopamine.
- Parthanatos wikiPageWikiLink Downregulation_and_upregulation.
- Parthanatos wikiPageWikiLink Enzyme.
- Parthanatos wikiPageWikiLink Eukaryote.
- Parthanatos wikiPageWikiLink Excitotoxicity.
- Parthanatos wikiPageWikiLink Genomic_stress.
- Parthanatos wikiPageWikiLink Genotoxicity.
- Parthanatos wikiPageWikiLink Helicase.
- Parthanatos wikiPageWikiLink Hepatotoxicity.
- Parthanatos wikiPageWikiLink Histone.
- Parthanatos wikiPageWikiLink Homeostasis.
- Parthanatos wikiPageWikiLink Hydrogen_peroxide.
- Parthanatos wikiPageWikiLink Hyperglycemia.
- Parthanatos wikiPageWikiLink Insulin.
- Parthanatos wikiPageWikiLink Isoquinolindione.
- Parthanatos wikiPageWikiLink MPTP.
- Parthanatos wikiPageWikiLink Midazoquinolinone.
- Parthanatos wikiPageWikiLink Mitochondrial_fission.
- Parthanatos wikiPageWikiLink Mitochondrion.
- Parthanatos wikiPageWikiLink Mitosis.
- Parthanatos wikiPageWikiLink Mutation.
- Parthanatos wikiPageWikiLink Myocardial_infarction.
- Parthanatos wikiPageWikiLink N-terminus.
- Parthanatos wikiPageWikiLink Necrosis.
- Parthanatos wikiPageWikiLink Nervous_system.
- Parthanatos wikiPageWikiLink Neuron.
- Parthanatos wikiPageWikiLink Neurotoxicity.
- Parthanatos wikiPageWikiLink Neurotoxin.
- Parthanatos wikiPageWikiLink Nicotinamide_adenine_dinucleotide.
- Parthanatos wikiPageWikiLink Nitric_oxide.
- Parthanatos wikiPageWikiLink Nuclear_translocation.
- Parthanatos wikiPageWikiLink Obesity.
- Parthanatos wikiPageWikiLink PARG.
- Parthanatos wikiPageWikiLink PARP1.
- Parthanatos wikiPageWikiLink Pancreas.
- Parthanatos wikiPageWikiLink Parkinsonism.
- Parthanatos wikiPageWikiLink Parkinsons_disease.
- Parthanatos wikiPageWikiLink Peroxynitrite.
- Parthanatos wikiPageWikiLink Polymer.
- Parthanatos wikiPageWikiLink Post-transcriptional_modification.
- Parthanatos wikiPageWikiLink Protein_domain.
- Parthanatos wikiPageWikiLink Pyruvic_acid.
- Parthanatos wikiPageWikiLink Reactive_oxygen_species.
- Parthanatos wikiPageWikiLink Stereoisomerism.
- Parthanatos wikiPageWikiLink Streptozotocin.
- Parthanatos wikiPageWikiLink Stroke.
- Parthanatos wikiPageWikiLink Syndrome.
- Parthanatos wikiPageWikiLink Thanatos.
- Parthanatos wikiPageWikiLink Topoisomerase.
- Parthanatos wikiPageWikiLink Toxin.
- Parthanatos wikiPageWikiLink Transcription_(genetics).
- Parthanatos wikiPageWikiLink Transcription_factor.
- Parthanatos wikiPageWikiLink Zinc_finger.
- Parthanatos wikiPageWikiLink File:PARP1proteindomainbreakdown.png.
- Parthanatos wikiPageWikiLinkText "Parthanatos".
- Parthanatos wikiPageUsesTemplate Template:Reflist.
- Parthanatos subject Category:Cellular_processes.
- Parthanatos subject Category:Medical_aspects_of_death.
- Parthanatos hypernym Form.
- Parthanatos comment "Parthanatos (derived from the Greek Θάνατος, “Death”) is a form of programmed cell death that is distinct from other cell death processes such as necrosis and apoptosis. While necrosis is caused by acute cell injury resulting in traumatic cell death and apoptosis is a highly controlled process signalled by apoptotic intracellular signals, parthanatos is caused by the accumulation of PAR and the nuclear translocation of apoptosis-inducing factor (AIF) from mitochondria.".
- Parthanatos label "Parthanatos".
- Parthanatos wasDerivedFrom Parthanatos?oldid=705295418.
- Parthanatos isPrimaryTopicOf Parthanatos.