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- Osteolathyrism abstract "Osteolathyrism is a collagen cross-linking deficiency brought on by dietary over-reliance on the seeds of Lathyrus sativus or grass pea, a legume often grown as a famine crop in Asia and East Africa. Other members of the genus are also known to cause the disease, including L. sylvestris, L. cicera, and L. clymenum. L. sativus grows well under famine conditions, often severe drought, where it is cultivated. The condition results in damage to bone and mesenchymal connective tissues.It is seen in people in combination with neurolathyrism and angiolathyrism in areas where famine demands reliance on a crop with known detrimental effects. It occurs in cattle and horses with diets overreliant upon the grass pea. Osteolathyrism is caused by a variety of osteolathyrogenic compounds, specifically excitatory amino-compounds. The most widely-studied of these compounds is beta-aminopropionitrile (BAPN), which exerts its deleterious effect by an unknown yet potently irreversible mechanism. Other instigators are ureides, semicarbazides and thiosemicarbazides, which are believed to chelate the prosthetic Cu(II)-bipyridine cofactor complex in the enzyme lysyl oxidase.".
- Osteolathyrism wikiPageID "9888853".
- Osteolathyrism wikiPageLength "3953".
- Osteolathyrism wikiPageOutDegree "56".
- Osteolathyrism wikiPageRevisionID "639587151".
- Osteolathyrism wikiPageWikiLink Acylurea.
- Osteolathyrism wikiPageWikiLink Aldehyde.
- Osteolathyrism wikiPageWikiLink Aldimine.
- Osteolathyrism wikiPageWikiLink Aldol_condensation.
- Osteolathyrism wikiPageWikiLink Amine.
- Osteolathyrism wikiPageWikiLink Aminopropionitrile.
- Osteolathyrism wikiPageWikiLink Angiolathyrism.
- Osteolathyrism wikiPageWikiLink Asia.
- Osteolathyrism wikiPageWikiLink Biomolecular_structure.
- Osteolathyrism wikiPageWikiLink Bipyridine.
- Osteolathyrism wikiPageWikiLink Bone.
- Osteolathyrism wikiPageWikiLink Carbonyl.
- Osteolathyrism wikiPageWikiLink Cartilage.
- Osteolathyrism wikiPageWikiLink Category:Structural_proteins.
- Osteolathyrism wikiPageWikiLink Category:Toxic_effect_of_noxious_substances_eaten_as_food.
- Osteolathyrism wikiPageWikiLink Cattle.
- Osteolathyrism wikiPageWikiLink Chelation.
- Osteolathyrism wikiPageWikiLink Child.
- Osteolathyrism wikiPageWikiLink Cofactor_(biochemistry).
- Osteolathyrism wikiPageWikiLink Collagen.
- Osteolathyrism wikiPageWikiLink Connective_tissue.
- Osteolathyrism wikiPageWikiLink Copper.
- Osteolathyrism wikiPageWikiLink Covalent_bond.
- Osteolathyrism wikiPageWikiLink Crop.
- Osteolathyrism wikiPageWikiLink Deficiency_(medicine).
- Osteolathyrism wikiPageWikiLink Dehydrohydroxylysinonorleucine.
- Osteolathyrism wikiPageWikiLink East_Africa.
- Osteolathyrism wikiPageWikiLink Electron.
- Osteolathyrism wikiPageWikiLink Enzyme.
- Osteolathyrism wikiPageWikiLink Famine.
- Osteolathyrism wikiPageWikiLink Famine_crop.
- Osteolathyrism wikiPageWikiLink Horse.
- Osteolathyrism wikiPageWikiLink Human.
- Osteolathyrism wikiPageWikiLink Ketone.
- Osteolathyrism wikiPageWikiLink Lathyrism.
- Osteolathyrism wikiPageWikiLink Lathyrus_cicera.
- Osteolathyrism wikiPageWikiLink Lathyrus_clymenum.
- Osteolathyrism wikiPageWikiLink Lathyrus_sativus.
- Osteolathyrism wikiPageWikiLink Lathyrus_sylvestris.
- Osteolathyrism wikiPageWikiLink Lysine.
- Osteolathyrism wikiPageWikiLink Lysyl_oxidase.
- Osteolathyrism wikiPageWikiLink Mesenchyme.
- Osteolathyrism wikiPageWikiLink Mesoderm.
- Osteolathyrism wikiPageWikiLink Paralysis.
- Osteolathyrism wikiPageWikiLink Pregnancy.
- Osteolathyrism wikiPageWikiLink Redox.
- Osteolathyrism wikiPageWikiLink Saturation_(chemistry).
- Osteolathyrism wikiPageWikiLink Schiff_base.
- Osteolathyrism wikiPageWikiLink Semicarbazide.
- Osteolathyrism wikiPageWikiLinkText "osteolathyrism".
- Osteolathyrism wikiPageUsesTemplate Template:Expert-subject.
- Osteolathyrism wikiPageUsesTemplate Template:Reflist.
- Osteolathyrism subject Category:Structural_proteins.
- Osteolathyrism subject Category:Toxic_effect_of_noxious_substances_eaten_as_food.
- Osteolathyrism hypernym Deficiency.
- Osteolathyrism type Disease.
- Osteolathyrism comment "Osteolathyrism is a collagen cross-linking deficiency brought on by dietary over-reliance on the seeds of Lathyrus sativus or grass pea, a legume often grown as a famine crop in Asia and East Africa. Other members of the genus are also known to cause the disease, including L. sylvestris, L. cicera, and L. clymenum. L. sativus grows well under famine conditions, often severe drought, where it is cultivated.".
- Osteolathyrism label "Osteolathyrism".
- Osteolathyrism sameAs Q7107617.
- Osteolathyrism sameAs m.02pv_0s.
- Osteolathyrism sameAs Q7107617.
- Osteolathyrism wasDerivedFrom Osteolathyrism?oldid=639587151.
- Osteolathyrism isPrimaryTopicOf Osteolathyrism.