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- Ortho-iodohippurate abstract "Ortho-iodohippurate is an analogue p-aminohippuric acid for the determination of effective renal plasma flow. Labelled OIH has a significantly higher clearance than other radiopharmaceutical yet developed and is eminently suitable for renography. It is eliminated mainly by tubular secretion. In patients with normally functioning kidneys, 85% of the OIH may be found in the urine 30 minutes after intravenous injection.OIH was first labelled with 131I by Tubis and colleagues (Tubis, Posnick and Nordyke in 1960) and for many years this was the only radiopharmaceutical for renography. 131I has a half-life of 8 days and emits high-energy gamma rays (364 KeV) in addition to beta particles. These physical characteristics were acceptable for probe studies when quantities of the order 1-2 MBq (25-50 μCi) were administered, but they are far from ideal for gamma camera studies which demand a higher activity and a gamma ray emission of lower energy. The introduction of OIH labelled with 123I, with its short physical half-life (13 hours) and its gamma emission of 159 KeV has greatly improved the diagnostic potential of renal studies by combining the production of high-quality functional images with the ability to derive a renogram. The only factor limiting its widespread use is restricted availability and the expense involved in its cyclotron production.".
- Ortho-iodohippurate casNumber "147-58-0".
- Ortho-iodohippurate fdaUniiCode "3Y68K91A3M".
- Ortho-iodohippurate iupacName "2-[(2-iodobenzoyl)amino]acetic acid".
- Ortho-iodohippurate pubchem "8614".
- Ortho-iodohippurate thumbnail Iodohippurate.png?width=300.
- Ortho-iodohippurate wikiPageID "49233413".
- Ortho-iodohippurate wikiPageLength "3512".
- Ortho-iodohippurate wikiPageOutDegree "18".
- Ortho-iodohippurate wikiPageRevisionID "702116337".
- Ortho-iodohippurate wikiPageWikiLink Aminohippuric_acid.
- Ortho-iodohippurate wikiPageWikiLink Beta_particle.
- Ortho-iodohippurate wikiPageWikiLink Blood_plasma.
- Ortho-iodohippurate wikiPageWikiLink Category:Acetic_acids.
- Ortho-iodohippurate wikiPageWikiLink Category:Benzamides.
- Ortho-iodohippurate wikiPageWikiLink Clearance_(medicine).
- Ortho-iodohippurate wikiPageWikiLink Cyclotron.
- Ortho-iodohippurate wikiPageWikiLink Gamma_camera.
- Ortho-iodohippurate wikiPageWikiLink Gamma_ray.
- Ortho-iodohippurate wikiPageWikiLink Half-life.
- Ortho-iodohippurate wikiPageWikiLink Intravenous_therapy.
- Ortho-iodohippurate wikiPageWikiLink Kidney.
- Ortho-iodohippurate wikiPageWikiLink Medicinal_radiocompounds.
- Ortho-iodohippurate wikiPageWikiLink Radioisotope_renography.
- Ortho-iodohippurate wikiPageWikiLink Renal_physiology.
- Ortho-iodohippurate wikiPageWikiLink Urine.
- Ortho-iodohippurate wikiPageWikiLinkText "''ortho''-iodohippurate".
- Ortho-iodohippurate wikiPageWikiLinkText "Ortho-iodohippurate".
- Ortho-iodohippurate c "9".
- Ortho-iodohippurate casNumber "147".
- Ortho-iodohippurate chemspiderid "8295".
- Ortho-iodohippurate drugName "Iodohippurate".
- Ortho-iodohippurate excretion "renal".
- Ortho-iodohippurate h "8".
- Ortho-iodohippurate i "1".
- Ortho-iodohippurate inchi "InChI=1S/C9H8INO3/c10-7-4-2-1-3-6911-5-813/h1-4H,5H2,".
- Ortho-iodohippurate inchikey "CORFWQGVBFFZHF-UHFFFAOYSA-N".
- Ortho-iodohippurate iupacName "2".
- Ortho-iodohippurate molecularWeight "304.95".
- Ortho-iodohippurate n "1".
- Ortho-iodohippurate o "3".
- Ortho-iodohippurate pubchem "8614".
- Ortho-iodohippurate routesOfAdministration "intravenous".
- Ortho-iodohippurate smiles "C1=CC=CI".
- Ortho-iodohippurate synonyms "Iodohippuric acid, I Hippuran, I OIH, I-Hippuran, I-OIH, Iodobenzoylglycine, Sodium iodohippurate, Sodium o-iodohippurate, ortho Iodohippurate, ortho-Iodohippurate, Orthoiodohippurate, Radio Hippuran, Radio-Hippuran, RadioHippuran, Sodium Iodohippurate".
- Ortho-iodohippurate unii "3".
- Ortho-iodohippurate width "243".
- Ortho-iodohippurate wikiPageUsesTemplate Template:Diagnostic_agents.
- Ortho-iodohippurate wikiPageUsesTemplate Template:Drugbox.
- Ortho-iodohippurate wikiPageUsesTemplate Template:Reflist.
- Ortho-iodohippurate wikiPageUsesTemplate Template:Renal_physiology.
- Ortho-iodohippurate subject Category:Acetic_acids.
- Ortho-iodohippurate subject Category:Benzamides.
- Ortho-iodohippurate hypernym Acid.
- Ortho-iodohippurate type ChemicalCompound.
- Ortho-iodohippurate type ChemicalSubstance.
- Ortho-iodohippurate type Drug.
- Ortho-iodohippurate type ChemicalObject.
- Ortho-iodohippurate type Thing.
- Ortho-iodohippurate type Q8386.
- Ortho-iodohippurate comment "Ortho-iodohippurate is an analogue p-aminohippuric acid for the determination of effective renal plasma flow. Labelled OIH has a significantly higher clearance than other radiopharmaceutical yet developed and is eminently suitable for renography. It is eliminated mainly by tubular secretion.".
- Ortho-iodohippurate label "Ortho-iodohippurate".
- Ortho-iodohippurate wasDerivedFrom Ortho-iodohippurate?oldid=702116337.
- Ortho-iodohippurate depiction Iodohippurate.png.
- Ortho-iodohippurate isPrimaryTopicOf Ortho-iodohippurate.
- Ortho-iodohippurate name "Iodohippurate".