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- Mizoribine abstract "Mizoribine (INN, trade name Bredinin) is an immunosuppressive drug. The compound was first observed in Tokyo, Japan, in 1971. It is a natural product, first isolated from the mould Eupenicillium brefeldianum. Mizoribine (MZB) is an imidazole nucleoside that has been used in renal transplantation, and in steroid-resistant nephrotic syndrome, IgA nephropathy, lupus, as well as for adults with rheumatoid arthritis, lupus nephritis and other rheumatic diseases. MZB exerts its activity through selective inhibition of inosine monophosphate synthetase and guanosine monophosphate synthetase, resulting in the complete inhibition of guanine nucleotide synthesis without incorporation into nucleotides. It arrests DNA synthesis in the S phase of cellular division. Thus, MZB has less toxicity than azathioprine, another immunosuppressant used for some of the same diseases.".
- Mizoribine atcPrefix "none".
- Mizoribine casNumber "50924-49-7".
- Mizoribine fdaUniiCode "4JR41A10VP".
- Mizoribine iupacName "5-hydroxy-1-β-(D)-ribofuranosyl-1H-imidazole-4-carboxamide".
- Mizoribine pubchem "104762".
- Mizoribine thumbnail Mizoribine.png?width=300.
- Mizoribine wikiPageID "18634413".
- Mizoribine wikiPageLength "3772".
- Mizoribine wikiPageOutDegree "5".
- Mizoribine wikiPageRevisionID "670169471".
- Mizoribine wikiPageWikiLink Category:Immunosuppressants.
- Mizoribine wikiPageWikiLink Immunosuppressive_drug.
- Mizoribine wikiPageWikiLink International_nonproprietary_name.
- Mizoribine wikiPageWikiLink Japan.
- Mizoribine wikiPageWikiLink Penicillium_brefeldianum.
- Mizoribine wikiPageWikiLinkText "Mizoribine".
- Mizoribine wikiPageWikiLinkText "mizoribine".
- Mizoribine atcPrefix "none".
- Mizoribine c "9".
- Mizoribine casNumber "50924".
- Mizoribine chemspiderid "94571".
- Mizoribine h "13".
- Mizoribine inchi "1".
- Mizoribine inchikey "HZQDCMWJEBCWBR-UUOKFMHZBU".
- Mizoribine iupacName "5".
- Mizoribine kegg "D01392".
- Mizoribine legalStatus "Rx-only".
- Mizoribine molecularWeight "259.21".
- Mizoribine n "3".
- Mizoribine o "6".
- Mizoribine pubchem "104762".
- Mizoribine routesOfAdministration "Oral".
- Mizoribine smiles "C1=NCCN".
- Mizoribine stdinchi "1".
- Mizoribine stdinchikey "HZQDCMWJEBCWBR-UUOKFMHZSA-N".
- Mizoribine synonyms "(1-[-3,4-dihydroxy-5-oxolan-2-yl]-5-hydroxyimidazole-4-carboxamide)".
- Mizoribine unii "4".
- Mizoribine verifiedrevid "444901837".
- Mizoribine wikiPageUsesTemplate Template:Antineoplastic-drug-stub.
- Mizoribine wikiPageUsesTemplate Template:Cascite.
- Mizoribine wikiPageUsesTemplate Template:Drugbankcite.
- Mizoribine wikiPageUsesTemplate Template:Drugbox.
- Mizoribine wikiPageUsesTemplate Template:Drugs.com.
- Mizoribine wikiPageUsesTemplate Template:Fdacite.
- Mizoribine wikiPageUsesTemplate Template:Immunosuppressants.
- Mizoribine wikiPageUsesTemplate Template:Keggcite.
- Mizoribine wikiPageUsesTemplate Template:Reflist.
- Mizoribine subject Category:Immunosuppressants.
- Mizoribine hypernym Drug.
- Mizoribine type ChemicalSubstance.
- Mizoribine type Drug.
- Mizoribine type Chemical.
- Mizoribine type Drug.
- Mizoribine type Immunosuppressant.
- Mizoribine type Redirect.
- Mizoribine type ChemicalObject.
- Mizoribine type Thing.
- Mizoribine type Q8386.
- Mizoribine comment "Mizoribine (INN, trade name Bredinin) is an immunosuppressive drug. The compound was first observed in Tokyo, Japan, in 1971. It is a natural product, first isolated from the mould Eupenicillium brefeldianum. Mizoribine (MZB) is an imidazole nucleoside that has been used in renal transplantation, and in steroid-resistant nephrotic syndrome, IgA nephropathy, lupus, as well as for adults with rheumatoid arthritis, lupus nephritis and other rheumatic diseases.".
- Mizoribine label "Mizoribine".
- Mizoribine sameAs Q6884708.
- Mizoribine sameAs ミゾリビン.
- Mizoribine sameAs m.04gp88h.
- Mizoribine sameAs Mizoribin.
- Mizoribine sameAs Mizoribin.
- Mizoribine sameAs Q6884708.
- Mizoribine wasDerivedFrom Mizoribine?oldid=670169471.
- Mizoribine depiction Mizoribine.png.
- Mizoribine isPrimaryTopicOf Mizoribine.