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- Mesoplasma_florum_riboswitch abstract "Riboswitches are cis-acting regulatory elements located within the 5’UTR of mRNA transcripts. These regulatory elements bind small molecules which results in a conformational change within the 5’UTR of the mRNA. The changes in the mRNA secondary structure subsequently result in changes in the expression of the adjacent open reading frame. Bioinformatic studies have identified several riboswitches present in M. florum. These riboswitches have been mapped to regions located upstream of the guaAB operon and resemble purine riboswitches. The riboswitches identified in M. florum can be classed as novel riboswitches as they deviate in sequence and structure within the loops regions that are required in aptamer binding compared to conventional purine riboswitches. Mutagenesis confirmed that changing nucleotides within the loop regions of this riboswitch altered the specificity for ligand binding. This study showed that the novel riboswitches have a greater diversity in ligands they bind as they were found to bind alternative ligands such as nucleosides. The novel riboswitches were all shown to lie upstream of a putative intrinsic terminator stem and this indicates that these riboswitches control transcription termination. Comparative genomics has shown that these novel riboswitches are exclusive found in M. florum and not present in other strains of bacteria.".
- Mesoplasma_florum_riboswitch thumbnail MFR_secondary_structure.jpg?width=300.
- Mesoplasma_florum_riboswitch wikiPageID "24015851".
- Mesoplasma_florum_riboswitch wikiPageLength "2555".
- Mesoplasma_florum_riboswitch wikiPageOutDegree "17".
- Mesoplasma_florum_riboswitch wikiPageRevisionID "699354474".
- Mesoplasma_florum_riboswitch wikiPageWikiLink Bacteria.
- Mesoplasma_florum_riboswitch wikiPageWikiLink Bioinformatics.
- Mesoplasma_florum_riboswitch wikiPageWikiLink Biomolecular_structure.
- Mesoplasma_florum_riboswitch wikiPageWikiLink Category:Riboswitch.
- Mesoplasma_florum_riboswitch wikiPageWikiLink Cis-Regulatory_element.
- Mesoplasma_florum_riboswitch wikiPageWikiLink Conserved_sequence.
- Mesoplasma_florum_riboswitch wikiPageWikiLink Genomics.
- Mesoplasma_florum_riboswitch wikiPageWikiLink Messenger_RNA.
- Mesoplasma_florum_riboswitch wikiPageWikiLink Mutagenesis.
- Mesoplasma_florum_riboswitch wikiPageWikiLink Nucleoside.
- Mesoplasma_florum_riboswitch wikiPageWikiLink Purine_riboswitch.
- Mesoplasma_florum_riboswitch wikiPageWikiLink Regulatory_sequence.
- Mesoplasma_florum_riboswitch wikiPageWikiLink Riboswitch.
- Mesoplasma_florum_riboswitch wikiPageWikiLink Transcription_(genetics).
- Mesoplasma_florum_riboswitch wikiPageWikiLink Untranslated_region.
- Mesoplasma_florum_riboswitch caption "Predicted secondary structure and sequence conservation of MFR".
- Mesoplasma_florum_riboswitch id "RF01510".
- Mesoplasma_florum_riboswitch name "M. florum riboswitch".
- Mesoplasma_florum_riboswitch name "Mesoplasma florum riboswitch".
- Mesoplasma_florum_riboswitch rfam "RF01510".
- Mesoplasma_florum_riboswitch rnaType Cis-Regulatory_element.
- Mesoplasma_florum_riboswitch rnaType Riboswitch.
- Mesoplasma_florum_riboswitch symbol "MFR".
- Mesoplasma_florum_riboswitch taxDomain Bacteria.
- Mesoplasma_florum_riboswitch wikiPageUsesTemplate Template:GO.
- Mesoplasma_florum_riboswitch wikiPageUsesTemplate Template:Infobox_rfam.
- Mesoplasma_florum_riboswitch wikiPageUsesTemplate Template:Orphan.
- Mesoplasma_florum_riboswitch wikiPageUsesTemplate Template:Reflist.
- Mesoplasma_florum_riboswitch wikiPageUsesTemplate Template:Rfam.
- Mesoplasma_florum_riboswitch wikiPageUsesTemplate Template:SO.
- Mesoplasma_florum_riboswitch subject Category:Riboswitch.
- Mesoplasma_florum_riboswitch hypernym Elements.
- Mesoplasma_florum_riboswitch type MilitaryUnit.
- Mesoplasma_florum_riboswitch type Element.
- Mesoplasma_florum_riboswitch comment "Riboswitches are cis-acting regulatory elements located within the 5’UTR of mRNA transcripts. These regulatory elements bind small molecules which results in a conformational change within the 5’UTR of the mRNA. The changes in the mRNA secondary structure subsequently result in changes in the expression of the adjacent open reading frame. Bioinformatic studies have identified several riboswitches present in M. florum.".
- Mesoplasma_florum_riboswitch label "Mesoplasma florum riboswitch".
- Mesoplasma_florum_riboswitch sameAs Q6821569.
- Mesoplasma_florum_riboswitch sameAs m.07k9c90.
- Mesoplasma_florum_riboswitch sameAs Q6821569.
- Mesoplasma_florum_riboswitch wasDerivedFrom Mesoplasma_florum_riboswitch?oldid=699354474.
- Mesoplasma_florum_riboswitch depiction MFR_secondary_structure.jpg.
- Mesoplasma_florum_riboswitch isPrimaryTopicOf Mesoplasma_florum_riboswitch.