Matches in DBpedia 2016-04 for { <http://dbpedia.org/resource/MTORC1> ?p ?o }
- MTORC1 abstract "mTORC1, also known as mammalian target of rapamycin complex 1 or mechanistic target of rapamycin complex 1, is a protein complex that functions as a nutrient/energy/redox sensor and controls protein synthesis.mTOR Complex 1 (mTORC1) is composed of mTOR itself, regulatory-associated protein of mTOR (Raptor), mammalian lethal with SEC13 protein 8 (MLST8) and the recently identified PRAS40 and DEPTOR. This complex embodies the classic functions of mTOR, namely as a nutrient/energy/redox sensor and controller of protein synthesis. The activity of this complex is controlled by insulin, growth factors, amino acids (particularly leucine), and oxidative stress.The role of mTORC1 is to activate translation of proteins. In order for cells to grow and proliferate by manufacturing more proteins, the cells must ensure that they have the resources available for protein production. Thus, for protein production, and therefore mTORC1 activation, cells must have adequate energy resources, nutrient availability, oxygen abundance, and proper growth factors in order for mRNA translation to begin.".
- MTORC1 arm "p".
- MTORC1 arm "q".
- MTORC1 band "25.3".
- MTORC1 band "36".
- MTORC1 chromosome "1".
- MTORC1 chromosome "17".
- MTORC1 ecNumber "2.7.11.1".
- MTORC1 entrezgene "2475".
- MTORC1 entrezgene "57521".
- MTORC1 hgncid "30287".
- MTORC1 hgncid "3942".
- MTORC1 omim "601231".
- MTORC1 omim "607130".
- MTORC1 refseq "NM_001163034.1".
- MTORC1 refseq "NM_004958".
- MTORC1 symbol "FRAP, FRAP2, FRAP1".
- MTORC1 symbol "KOG1, Mip1".
- MTORC1 symbol "MTOR".
- MTORC1 symbol "RPTOR".
- MTORC1 thumbnail Activation_of_mTORC1_at_the_Lysosome.jpg?width=300.
- MTORC1 uniprot "P42345".
- MTORC1 uniprot "Q8N122".
- MTORC1 wikiPageID "38402739".
- MTORC1 wikiPageLength "54518".
- MTORC1 wikiPageOutDegree "170".
- MTORC1 wikiPageRevisionID "705428660".
- MTORC1 wikiPageWikiLink 14-3-3_protein.
- MTORC1 wikiPageWikiLink AKT1S1.
- MTORC1 wikiPageWikiLink AMP-activated_protein_kinase.
- MTORC1 wikiPageWikiLink ATP-binding_motif.
- MTORC1 wikiPageWikiLink Adenosine_monophosphate.
- MTORC1 wikiPageWikiLink Adenosine_triphosphate.
- MTORC1 wikiPageWikiLink Ageing.
- MTORC1 wikiPageWikiLink PKB_signaling_pathway.
- MTORC1 wikiPageWikiLink Alcohol.
- MTORC1 wikiPageWikiLink Amino_acid.
- MTORC1 wikiPageWikiLink Atg1.
- MTORC1 wikiPageWikiLink Autophagy.
- MTORC1 wikiPageWikiLink Autophagy-related_protein_13.
- MTORC1 wikiPageWikiLink BTRC_(gene).
- MTORC1 wikiPageWikiLink B_cell.
- MTORC1 wikiPageWikiLink Beta_cell.
- MTORC1 wikiPageWikiLink Caffeine.
- MTORC1 wikiPageWikiLink Cancer.
- MTORC1 wikiPageWikiLink Cardiovascular_disease.
- MTORC1 wikiPageWikiLink Category:EC_2.7.11.
- MTORC1 wikiPageWikiLink Category:Human_proteins.
- MTORC1 wikiPageWikiLink Category:Protein_complexes.
- MTORC1 wikiPageWikiLink Category:Tor_signaling_pathway.
- MTORC1 wikiPageWikiLink Cell_membrane.
- MTORC1 wikiPageWikiLink Cellular_respiration.
- MTORC1 wikiPageWikiLink Clinical_trial.
- MTORC1 wikiPageWikiLink Curcumin.
- MTORC1 wikiPageWikiLink Cytokine.
- MTORC1 wikiPageWikiLink Cytoplasm.
- MTORC1 wikiPageWikiLink DDIT4.
- MTORC1 wikiPageWikiLink DEPDC5.
- MTORC1 wikiPageWikiLink DEPTOR.
- MTORC1 wikiPageWikiLink Diabetes_mellitus.
- MTORC1 wikiPageWikiLink EIF4A.
- MTORC1 wikiPageWikiLink EIF4B.
- MTORC1 wikiPageWikiLink EIF4E.
- MTORC1 wikiPageWikiLink EIF4EBP1.
- MTORC1 wikiPageWikiLink EIF4G.
- MTORC1 wikiPageWikiLink Electron_transport_chain.
- MTORC1 wikiPageWikiLink Electrophile.
- MTORC1 wikiPageWikiLink Embryonic.
- MTORC1 wikiPageWikiLink Endosome.
- MTORC1 wikiPageWikiLink Epigallocatechin_gallate.
- MTORC1 wikiPageWikiLink Eukaryote.
- MTORC1 wikiPageWikiLink Eukaryotic_initiation_factor.
- MTORC1 wikiPageWikiLink Eukaryotic_small_ribosomal_subunit_(40S).
- MTORC1 wikiPageWikiLink Everolimus.
- MTORC1 wikiPageWikiLink Exon.
- MTORC1 wikiPageWikiLink Exon_junction_complex.
- MTORC1 wikiPageWikiLink Extracellular_signal-regulated_kinases.
- MTORC1 wikiPageWikiLink Farnesol.
- MTORC1 wikiPageWikiLink File:Activation_of_mTORC1_at_the_Lysosome.jpg.
- MTORC1 wikiPageWikiLink File:Downstream_of_mTORC1.png.
- MTORC1 wikiPageWikiLink File:General_mTORC1_Pathway.jpg.
- MTORC1 wikiPageWikiLink Five_prime_untranslated_region.
- MTORC1 wikiPageWikiLink Food_and_Drug_Administration.
- MTORC1 wikiPageWikiLink GRB2.
- MTORC1 wikiPageWikiLink GSK3B.
- MTORC1 wikiPageWikiLink GTPase.
- MTORC1 wikiPageWikiLink GTPase-activating_protein.
- MTORC1 wikiPageWikiLink Glucose.
- MTORC1 wikiPageWikiLink Glycolysis.
- MTORC1 wikiPageWikiLink Guanosine_triphosphate.
- MTORC1 wikiPageWikiLink HIF1A.
- MTORC1 wikiPageWikiLink Helicase.
- MTORC1 wikiPageWikiLink Hematopoietic_stem_cell.
- MTORC1 wikiPageWikiLink Hypoxia_(medical).
- MTORC1 wikiPageWikiLink IKK2.
- MTORC1 wikiPageWikiLink Immune_system.
- MTORC1 wikiPageWikiLink Immunosuppression.
- MTORC1 wikiPageWikiLink Insulin-like_growth_factor.
- MTORC1 wikiPageWikiLink Insulin-like_growth_factor_1.
- MTORC1 wikiPageWikiLink Insulin_receptor.