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- LR132 abstract "LR132 or (+)-3,4-dichloro-N-[(1R,2S)-2-(1-pyrrolidinyl)cyclohexyl]benzeneethanamine is a selective sigma receptor antagonist, with a reported binding affinity of Ki = 2 ± 0.1 nM for the sigma-1 receptor and more than 350 times selectivity over the sigma-2 receptor.Consistent with other reported sigma receptor antagonists, pretreating Swiss Webster mice with LR132 significantly decreases the convulsivity and lethality of cocaine.".
- LR132 casNumber "135211-15-3".
- LR132 iupacName "(+)-3,4-dichloro-N-[(1R,2S)-2-(1-pyrrolidinyl)cyclohexyl]benzeneethanamine".
- LR132 thumbnail LR132.png?width=300.
- LR132 wikiPageID "36174213".
- LR132 wikiPageLength "2117".
- LR132 wikiPageOutDegree "11".
- LR132 wikiPageRevisionID "608540771".
- LR132 wikiPageWikiLink Antagonist.
- LR132 wikiPageWikiLink BD1008.
- LR132 wikiPageWikiLink BD1031.
- LR132 wikiPageWikiLink Category:Sigma_antagonists.
- LR132 wikiPageWikiLink Cocaine.
- LR132 wikiPageWikiLink Ligand_(biochemistry).
- LR132 wikiPageWikiLink Sigma-1_receptor.
- LR132 wikiPageWikiLink Sigma-2_receptor.
- LR132 wikiPageWikiLink Sigma_receptor.
- LR132 wikiPageWikiLinkText "LR132".
- LR132 c "18".
- LR132 casNumber "135211".
- LR132 cl "2".
- LR132 h "26".
- LR132 iupacName "-34".
- LR132 molecularWeight "341.32".
- LR132 n "2".
- LR132 wikiPageUsesTemplate Template:Drugbox.
- LR132 wikiPageUsesTemplate Template:Reflist.
- LR132 subject Category:Sigma_antagonists.
- LR132 hypernym Antagonist.
- LR132 type ChemicalSubstance.
- LR132 type Drug.
- LR132 type Antagonist.
- LR132 type Chemical.
- LR132 type ChemicalObject.
- LR132 type Thing.
- LR132 type Q8386.
- LR132 comment "LR132 or (+)-3,4-dichloro-N-[(1R,2S)-2-(1-pyrrolidinyl)cyclohexyl]benzeneethanamine is a selective sigma receptor antagonist, with a reported binding affinity of Ki = 2 ± 0.1 nM for the sigma-1 receptor and more than 350 times selectivity over the sigma-2 receptor.Consistent with other reported sigma receptor antagonists, pretreating Swiss Webster mice with LR132 significantly decreases the convulsivity and lethality of cocaine.".
- LR132 label "LR132".
- LR132 sameAs Q6459781.
- LR132 sameAs m.0k0n_23.
- LR132 sameAs Q6459781.
- LR132 wasDerivedFrom LR132?oldid=608540771.
- LR132 depiction LR132.png.
- LR132 isPrimaryTopicOf LR132.
