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- Kifunensine abstract "Kifunensine is an alkaloid originally isolated from Kitasatosporia kifunense, an actinobacterium (formerly called an actinomycete). It is a neutral, stable compound.Kifunensine is a potent inhibitor of the mannosidase I enzyme and is primarily used in cell culture to make high mannose glycoproteins. Inside a cell, it prevents endoplasmic reticulum mannosidase I (ERM1) from trimming mannose residues from precursor glycoproteins. Kifunensine shows no inhibitory action against mannosidase II or the endoplasmic reticulum alpha-mannosidase, and it weakly inhibits arylmannosidase.When incorporated in cell culture media, kifunensine has shown no significant impact on cell growth or glycoprotein production yield.Kifunensine has shown potential for treatment of sarcoglycanopathies and lysosomal storage disorders.".
- Kifunensine iupacName "(5R,6R,7S,8R,8aS)-Hexahydro-6,7,8-trihydroxy-5-(hydroxymethyl)-imidazo[1,2-a]pyridine-2,3-dione".
- Kifunensine thumbnail Kifunensine.svg?width=300.
- Kifunensine wikiPageID "40123041".
- Kifunensine wikiPageLength "11784".
- Kifunensine wikiPageOutDegree "24".
- Kifunensine wikiPageRevisionID "701952316".
- Kifunensine wikiPageWikiLink Actinobacteria.
- Kifunensine wikiPageWikiLink Africa.
- Kifunensine wikiPageWikiLink Alkaloid.
- Kifunensine wikiPageWikiLink Apoptosis.
- Kifunensine wikiPageWikiLink Brazil.
- Kifunensine wikiPageWikiLink Category:Alcohols.
- Kifunensine wikiPageWikiLink Category:Alkaloids.
- Kifunensine wikiPageWikiLink Europe.
- Kifunensine wikiPageWikiLink European_Medicines_Agency.
- Kifunensine wikiPageWikiLink European_Union.
- Kifunensine wikiPageWikiLink Fibroblast.
- Kifunensine wikiPageWikiLink Gauchers_disease.
- Kifunensine wikiPageWikiLink Glycoprotein.
- Kifunensine wikiPageWikiLink Japan.
- Kifunensine wikiPageWikiLink Lysosomal_storage_disease.
- Kifunensine wikiPageWikiLink Mannosyl-oligosaccharide_1,2-alpha-mannosidase.
- Kifunensine wikiPageWikiLink Mannosyl-oligosaccharide_1,3-1,6-alpha-mannosidase.
- Kifunensine wikiPageWikiLink N-Acetylmannosamine.
- Kifunensine wikiPageWikiLink Orphan_drug.
- Kifunensine wikiPageWikiLink Rice_University.
- Kifunensine wikiPageWikiLink Sarcoglycanopathy.
- Kifunensine wikiPageWikiLink Tay–Sachs_disease.
- Kifunensine wikiPageWikiLinkText "Kifunensine".
- Kifunensine imagealt "Kifunensine".
- Kifunensine imagefile "Kifunensine.svg".
- Kifunensine iupacname "-Hexahydro-6,7,8-trihydroxy-5--imidazo[1,2-a]pyridine-2,3-dione".
- Kifunensine wikiPageUsesTemplate Template:Chembox.
- Kifunensine wikiPageUsesTemplate Template:Chembox_Hazards.
- Kifunensine wikiPageUsesTemplate Template:Chembox_Identifiers.
- Kifunensine wikiPageUsesTemplate Template:Chembox_Properties.
- Kifunensine wikiPageUsesTemplate Template:Reflist.
- Kifunensine subject Category:Alcohols.
- Kifunensine subject Category:Alkaloids.
- Kifunensine hypernym Alkaloid.
- Kifunensine type ChemicalCompound.
- Kifunensine type ChemicalSubstance.
- Kifunensine type ChemicalObject.
- Kifunensine type Thing.
- Kifunensine type Q11173.
- Kifunensine comment "Kifunensine is an alkaloid originally isolated from Kitasatosporia kifunense, an actinobacterium (formerly called an actinomycete). It is a neutral, stable compound.Kifunensine is a potent inhibitor of the mannosidase I enzyme and is primarily used in cell culture to make high mannose glycoproteins. Inside a cell, it prevents endoplasmic reticulum mannosidase I (ERM1) from trimming mannose residues from precursor glycoproteins.".
- Kifunensine label "Kifunensine".
- Kifunensine sameAs Q15303950.
- Kifunensine sameAs m.0wkr893.
- Kifunensine sameAs Kifunensin.
- Kifunensine sameAs Kifunensin.
- Kifunensine sameAs Q15303950.
- Kifunensine wasDerivedFrom Kifunensine?oldid=701952316.
- Kifunensine depiction Kifunensine.svg.
- Kifunensine isPrimaryTopicOf Kifunensine.