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- KLC1 abstract "Kinesin light chain 1 is a protein that in humans is encoded by the KLC1 gene.Conventional kinesin is a tetrameric molecule composed of two heavy chains and two light chains, and transports various cargos along microtubules toward their plus ends. The heavy chains provide the motor activity, while the light chains bind to various cargos. This gene encodes a member of the kinesin light chain family. It associates with kinesin heavy chain through an N-terminal domain, and six tetratricopeptide repeat (TPR) motifs are thought to be involved in binding of cargos such as vesicles, mitochondria, and the Golgi complex. Thus, kinesin light chains function as adapter molecules and not motors per se. Although previously named \"kinesin 2\", this gene is not a member of the kinesin-2 / kinesin heavy chain subfamily of kinesin motor proteins. Extensive alternative splicing produces isoforms with different C-termini that are proposed to bind to different cargos; however, the full-length nature of some of these variants has not been determined.".
- KLC1 entrezgene "3831".
- KLC1 wikiPageID "14777027".
- KLC1 wikiPageLength "11311".
- KLC1 wikiPageOutDegree "6".
- KLC1 wikiPageRevisionID "686966815".
- KLC1 wikiPageWikiLink Gene.
- KLC1 wikiPageWikiLink KIF5A.
- KLC1 wikiPageWikiLink KIF5B.
- KLC1 wikiPageWikiLink MAPK8IP3.
- KLC1 wikiPageWikiLink Protein.
- KLC1 wikiPageWikiLink Protein–protein_interaction.
- KLC1 wikiPageWikiLinkText "KLC1".
- KLC1 requireManualInspection "no".
- KLC1 summaryText "Conventional kinesin is a tetrameric molecule composed of two heavy chains and two light chains, and transports various cargos along microtubules toward their plus ends. The heavy chains provide the motor activity, while the light chains bind to various cargos. This gene encodes a member of the kinesin light chain family. It associates with kinesin heavy chain through an N-terminal domain, and six tetratricopeptide repeat motifs are thought to be involved in binding of cargos such as vesicles, mitochondria, and the Golgi complex. Thus, kinesin light chains function as adapter molecules and not motors per se. Although previously named "kinesin 2", this gene is not a member of the kinesin-2 / kinesin heavy chain subfamily of kinesin motor proteins. Extensive alternative splicing produces isoforms with different C-termini that are proposed to bind to different cargos; however, the full-length nature of some of these variants has not been determined.".
- KLC1 updateCitations "yes".
- KLC1 updatePage "yes".
- KLC1 updateProteinBox "yes".
- KLC1 updateSummary "yes".
- KLC1 wikiPageUsesTemplate Template:Cite_journal.
- KLC1 wikiPageUsesTemplate Template:PBB.
- KLC1 wikiPageUsesTemplate Template:PBB_Controls.
- KLC1 wikiPageUsesTemplate Template:PBB_Further_reading.
- KLC1 wikiPageUsesTemplate Template:PBB_Summary.
- KLC1 wikiPageUsesTemplate Template:Refbegin.
- KLC1 wikiPageUsesTemplate Template:Refend.
- KLC1 wikiPageUsesTemplate Template:Reflist.
- KLC1 hypernym Protein.
- KLC1 type Biomolecule.
- KLC1 type Protein.
- KLC1 type Thing.
- KLC1 type Q206229.
- KLC1 type Q8054.
- KLC1 comment "Kinesin light chain 1 is a protein that in humans is encoded by the KLC1 gene.Conventional kinesin is a tetrameric molecule composed of two heavy chains and two light chains, and transports various cargos along microtubules toward their plus ends. The heavy chains provide the motor activity, while the light chains bind to various cargos. This gene encodes a member of the kinesin light chain family.".
- KLC1 label "KLC1".
- KLC1 sameAs Q18028325.
- KLC1 sameAs m.03gxp2p.
- KLC1 sameAs Q18028325.
- KLC1 wasDerivedFrom KLC1?oldid=686966815.
- KLC1 isPrimaryTopicOf KLC1.