DBpedia 2016-04

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Immunomics abstract "Immunomics is the study of immune system regulation and response to pathogens using genome-wide approaches. With the rise of genomic and proteomic technologies, scientists have been able to visualize biological networks and infer interrelationships between genes and/or proteins; recently, these technologies have been used to help better understand how the immune system functions and how it is regulated. Two thirds of the genome is active in one or more immune cell types and less than 1% of genes are uniquely expressed in a given type of cell. Therefore, it is critical that the expression patterns of these immune cell types be deciphered in the context of a network, and not as an individual, so that their roles be correctly characterized and related to one another. Defects of the immune system such as autoimmune diseases, immunodeficiency, and malignancies can benefit from genomic insights on pathological processes. For example, analyzing the systematic variation of gene expression can relate these patterns with specific diseases and gene networks important for immune functions.Traditionally, scientists studying the immune system have had to search for antigens on an individual basis and identify the protein sequence of these antigens (“epitopes”) that would stimulate an immune response. This procedure required that antigens be isolated from whole cells, digested into smaller fragments, and tested against T- and B-cells to observe T- and B- cell responses. These classical approaches could only visualize this system as a static condition and required a large amount of time and labor.Immunomics has made this approach easier by its ability to look at the immune system as a whole and characterize it as a dynamic model. It has revealed that some of the immune system’s most distinguishing features are the continuous motility, turnover, and plasticity of its constituent cells. In addition, current genomic technologies, like microarrays, can capture immune system gene expression over time and can trace interactions of microorganisms with cells of the innate immune system. New, proteomic approaches, including T-cell and B-cells-epitope mapping, can also accelerate the pace at which scientists discover antibody-antigen relationships.".
Immunomics wikiPageID "33769881".
Immunomics wikiPageLength "30752".
Immunomics wikiPageOutDegree "77".
Immunomics wikiPageRevisionID "705596498".
Immunomics wikiPageWikiLink Adaptive_immune_system.
Immunomics wikiPageWikiLink Allergy.
Immunomics wikiPageWikiLink Antibody.
Immunomics wikiPageWikiLink Antigen.
Immunomics wikiPageWikiLink Antigen-presenting_cell.
Immunomics wikiPageWikiLink Apoptosis.
Immunomics wikiPageWikiLink Autoimmune_disease.
Immunomics wikiPageWikiLink Autoimmunity.
Immunomics wikiPageWikiLink BYSL.
Immunomics wikiPageWikiLink Bacillus_anthracis.
Immunomics wikiPageWikiLink C-Jun_N-terminal_kinases.
Immunomics wikiPageWikiLink Carcinogenesis.
Immunomics wikiPageWikiLink Category:Branches_of_immunology.
Immunomics wikiPageWikiLink Cell_cycle.
Immunomics wikiPageWikiLink Chemokine.
Immunomics wikiPageWikiLink Chlamydophila_pneumoniae.
Immunomics wikiPageWikiLink Complementary_DNA.
Immunomics wikiPageWikiLink Computational_immunology.
Immunomics wikiPageWikiLink Cytokine.
Immunomics wikiPageWikiLink Cytomegalovirus.
Immunomics wikiPageWikiLink Cytotoxic_T_cell.
Immunomics wikiPageWikiLink Dendritic_cell.
Immunomics wikiPageWikiLink Diffuse_large_B-cell_lymphoma.
Immunomics wikiPageWikiLink ELISA.
Immunomics wikiPageWikiLink ELISPOT.
Immunomics wikiPageWikiLink Endocrinology.
Immunomics wikiPageWikiLink Epitope.
Immunomics wikiPageWikiLink Epitope_mapping.
Immunomics wikiPageWikiLink Expressed_sequence_tag.
Immunomics wikiPageWikiLink Fibroblast.
Immunomics wikiPageWikiLink File:Lymphochip.jpg.
Immunomics wikiPageWikiLink Flow_cytometry.
Immunomics wikiPageWikiLink Genomics.
Immunomics wikiPageWikiLink Germinal_center.
Immunomics wikiPageWikiLink Helicobacter_pylori.
Immunomics wikiPageWikiLink Immune_system.
Immunomics wikiPageWikiLink Immunodeficiency.
Immunomics wikiPageWikiLink Immunogenicity.
Immunomics wikiPageWikiLink Immunome.
Immunomics wikiPageWikiLink Innate_immune_system.
Immunomics wikiPageWikiLink Lymphocyte.
Immunomics wikiPageWikiLink Macrophage.
Immunomics wikiPageWikiLink Major_histocompatibility_complex.
Immunomics wikiPageWikiLink Microarray.
Immunomics wikiPageWikiLink Mitogen.
Immunomics wikiPageWikiLink Mitogen-activated_protein_kinase_kinase.
Immunomics wikiPageWikiLink Multiple_sclerosis.
Immunomics wikiPageWikiLink Myc.
Immunomics wikiPageWikiLink Mycobacterium_tuberculosis.
Immunomics wikiPageWikiLink NF-κB.
Immunomics wikiPageWikiLink NFAT.
Immunomics wikiPageWikiLink Natural_killer_cell.
Immunomics wikiPageWikiLink Neisseria_meningitidis.
Immunomics wikiPageWikiLink Oncogene.
Immunomics wikiPageWikiLink Open_reading_frame.
Immunomics wikiPageWikiLink Pathogen.
Immunomics wikiPageWikiLink Pathogenesis.
Immunomics wikiPageWikiLink Phagocytosis.
Immunomics wikiPageWikiLink Porphyromonas_gingivalis.
Immunomics wikiPageWikiLink Proteomics.
Immunomics wikiPageWikiLink RNA_interference.
Immunomics wikiPageWikiLink Serum_(blood).
Immunomics wikiPageWikiLink Streptococcus_pneumoniae.
Immunomics wikiPageWikiLink T_cell.
Immunomics wikiPageWikiLink T_helper_cell.
Immunomics wikiPageWikiLink Tetramer_staining.
Immunomics wikiPageWikiLink Vaccine.
Immunomics wikiPageWikiLink Vaccinia.
Immunomics wikiPageWikiLinkText "Immunomics".
Immunomics wikiPageWikiLinkText "immunomics".
Immunomics wikiPageUsesTemplate Template:Genomics.
Immunomics wikiPageUsesTemplate Template:Portal_bar.
Immunomics wikiPageUsesTemplate Template:Refimprove.
Immunomics wikiPageUsesTemplate Template:Reflist.
Immunomics subject Category:Branches_of_immunology.
Immunomics hypernym Study.
Immunomics type Book.
Immunomics type Specialty.
Immunomics comment "Immunomics is the study of immune system regulation and response to pathogens using genome-wide approaches. With the rise of genomic and proteomic technologies, scientists have been able to visualize biological networks and infer interrelationships between genes and/or proteins; recently, these technologies have been used to help better understand how the immune system functions and how it is regulated.".
Immunomics label "Immunomics".
Immunomics sameAs Q6005537.
Immunomics sameAs m.0hhtvnq.
Immunomics sameAs Q6005537.
Immunomics sameAs 免疫组学.
Immunomics wasDerivedFrom Immunomics?oldid=705596498.
Immunomics isPrimaryTopicOf Immunomics.