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- Imidazenil abstract "Imidazenil is an anxiolytic drug which is derived from the benzodiazepine family, and is most closely related to other imidazobenzodiazepines such as midazolam, flumazenil and bretazenil.Imidazenil is a highly potent Benzodiazepine receptor partial agonist with an unusual profile of effects, producing some of the effects associated with normal benzodiazepines such as anticonvulsant and anxiolytic effects, yet without any notable sedative or amnestic effects. In fact, imidazenil blocks the sedative effects of diazepam, yet without lowering the convulsion threshold, and so potentially could be a more flexible antidote than the antagonist flumazenil which is commonly used to treat benzodiazepine overdose at present.This unusual profile of effects makes imidazenil potentially a very useful drug. In animal studies it has been shown to be an effective anxiolytic and strong anticonvulsant, yet without many of the side effects associated with other benzodiazepines; it does not produce tolerance or dependence, reverses the amnestic effects of conventional benzodiazepines, and does not potentiate the effects of alcohol.Imidazenil has not yet been developed commercially for use in humans, however it has been suggested as a safe and effective treatment for anxiety, a potent yet non-sedating anticonvulsant which might be particularly useful in the treatment of poisoning with organophosphate nerve agents, and as a novel treatment for schizophrenia.".
- Imidazenil atcPrefix "none".
- Imidazenil casNumber "151271-08-8".
- Imidazenil iupacName "6-(2-bromophenyl)-8-fluoro-4H-imidazo[1,5-a][1,4]benzodiazepine-3-carboxamide".
- Imidazenil pubchem "119194".
- Imidazenil thumbnail Imidazenil_structure.svg?width=300.
- Imidazenil wikiPageID "13351850".
- Imidazenil wikiPageLength "6479".
- Imidazenil wikiPageOutDegree "28".
- Imidazenil wikiPageRevisionID "697422162".
- Imidazenil wikiPageWikiLink Amnesia.
- Imidazenil wikiPageWikiLink Anticonvulsant.
- Imidazenil wikiPageWikiLink Anxiety.
- Imidazenil wikiPageWikiLink Anxiolytic.
- Imidazenil wikiPageWikiLink Benzodiazepine.
- Imidazenil wikiPageWikiLink Benzodiazepine_overdose.
- Imidazenil wikiPageWikiLink Bretazenil.
- Imidazenil wikiPageWikiLink Category:Amides.
- Imidazenil wikiPageWikiLink Category:Bromoarenes.
- Imidazenil wikiPageWikiLink Category:Fluoroarenes.
- Imidazenil wikiPageWikiLink Category:GABAA_receptor_positive_allosteric_modulators.
- Imidazenil wikiPageWikiLink Category:Imidazobenzodiazepines.
- Imidazenil wikiPageWikiLink Diazepam.
- Imidazenil wikiPageWikiLink Drug_tolerance.
- Imidazenil wikiPageWikiLink Flumazenil.
- Imidazenil wikiPageWikiLink GABAA_receptor.
- Imidazenil wikiPageWikiLink Midazolam.
- Imidazenil wikiPageWikiLink Nerve_agent.
- Imidazenil wikiPageWikiLink Partial_agonist.
- Imidazenil wikiPageWikiLink Physical_dependence.
- Imidazenil wikiPageWikiLink Schizophrenia.
- Imidazenil wikiPageWikiLink Sedative.
- Imidazenil wikiPageWikiLinkText "Imidazenil".
- Imidazenil wikiPageWikiLinkText "imidazenil".
- Imidazenil atcPrefix "none".
- Imidazenil br "1".
- Imidazenil c "18".
- Imidazenil casNumber "151271".
- Imidazenil chemspiderid "106482".
- Imidazenil f "1".
- Imidazenil h "12".
- Imidazenil image "Imidazenil ball-and-stick model.png".
- Imidazenil inchi "1".
- Imidazenil inchikey "OCJHYHKWUWSHEN-UHFFFAOYAC".
- Imidazenil iupacName "6".
- Imidazenil molecularWeight "399.216".
- Imidazenil n "4".
- Imidazenil o "1".
- Imidazenil pubchem "119194".
- Imidazenil smiles "Brc4ccccc4C/2=N/Cc1cCN".
- Imidazenil stdinchi "1".
- Imidazenil stdinchikey "OCJHYHKWUWSHEN-UHFFFAOYSA-N".
- Imidazenil verifiedrevid "447928757".
- Imidazenil width "200".
- Imidazenil wikiPageUsesTemplate Template:Anxiolytics.
- Imidazenil wikiPageUsesTemplate Template:Benzodiazepines.
- Imidazenil wikiPageUsesTemplate Template:Cascite.
- Imidazenil wikiPageUsesTemplate Template:Chemspidercite.
- Imidazenil wikiPageUsesTemplate Template:Drugbankcite.
- Imidazenil wikiPageUsesTemplate Template:Drugbox.
- Imidazenil wikiPageUsesTemplate Template:GABAAR_PAMs.
- Imidazenil wikiPageUsesTemplate Template:Reflist.
- Imidazenil wikiPageUsesTemplate Template:Stdinchicite.
- Imidazenil subject Category:Amides.
- Imidazenil subject Category:Bromoarenes.
- Imidazenil subject Category:Fluoroarenes.
- Imidazenil subject Category:GABAA_receptor_positive_allosteric_modulators.
- Imidazenil subject Category:Imidazobenzodiazepines.
- Imidazenil hypernym Drug.
- Imidazenil type ChemicalSubstance.
- Imidazenil type Drug.
- Imidazenil type Group.
- Imidazenil type Amide.
- Imidazenil type Drug.
- Imidazenil type Group.
- Imidazenil type Heterocycle.
- Imidazenil type Organofluoride.
- Imidazenil type Organohalide.
- Imidazenil type Organofluoride.
- Imidazenil type Organohalide.
- Imidazenil type ChemicalObject.
- Imidazenil type Thing.
- Imidazenil type Q8386.
- Imidazenil comment "Imidazenil is an anxiolytic drug which is derived from the benzodiazepine family, and is most closely related to other imidazobenzodiazepines such as midazolam, flumazenil and bretazenil.Imidazenil is a highly potent Benzodiazepine receptor partial agonist with an unusual profile of effects, producing some of the effects associated with normal benzodiazepines such as anticonvulsant and anxiolytic effects, yet without any notable sedative or amnestic effects.".
- Imidazenil label "Imidazenil".
- Imidazenil sameAs Q15409429.
- Imidazenil sameAs m.03c2kl6.
- Imidazenil sameAs Imidazenil.
- Imidazenil sameAs Imidazenil.
- Imidazenil sameAs Q15409429.
- Imidazenil wasDerivedFrom Imidazenil?oldid=697422162.
- Imidazenil depiction Imidazenil_structure.svg.
- Imidazenil isPrimaryTopicOf Imidazenil.