Matches in DBpedia 2016-04 for { <http://dbpedia.org/resource/IBNtxA> ?p ?o }
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- IBNtxA abstract "IBNtxA, or 3-iodobenzoyl naltrexamine, is an atypical opioid analgesic drug derived from naltrexone. In animal studies it produces potent analgesic effects that are blocked by levallorphan and so appear to be μ-opioid mediated, but it fails to produce constipation or respiratory depression, and is neither rewarding or aversive in conditioned place preference protocols. These unusual properties are thought to result from agonist action at a splice variant or heterodimer of the μ-opioid receptor, rather than at the classical full length form targeted by conventional opioid drugs.".
- IBNtxA atcPrefix "none".
- IBNtxA iupacName "N-[(4R,4aS,7R,7aR,12bS)-3-(cyclopropylmethyl)-4a,9-dihydroxy-1,2,4,5,6,7,7a,13-octahydro-4,12-methanobenzofuro[3,2-e]isoquinoline-7-yl]-3-iodobenzamide".
- IBNtxA pubchem "51003467".
- IBNtxA thumbnail IBNtxA_structure.png?width=300.
- IBNtxA wikiPageID "34044265".
- IBNtxA wikiPageLength "4176".
- IBNtxA wikiPageOutDegree "14".
- IBNtxA wikiPageRevisionID "695177984".
- IBNtxA wikiPageWikiLink Alternative_splicing.
- IBNtxA wikiPageWikiLink Analgesic.
- IBNtxA wikiPageWikiLink Category:Benzamides.
- IBNtxA wikiPageWikiLink Category:Mu-opioid_agonists.
- IBNtxA wikiPageWikiLink Category:Phenols.
- IBNtxA wikiPageWikiLink Category:Semisynthetic_opioids.
- IBNtxA wikiPageWikiLink Conditioned_place_preference.
- IBNtxA wikiPageWikiLink Constipation.
- IBNtxA wikiPageWikiLink Hypoventilation.
- IBNtxA wikiPageWikiLink Levallorphan.
- IBNtxA wikiPageWikiLink Naltrexone.
- IBNtxA wikiPageWikiLink Opioid.
- IBNtxA wikiPageWikiLink Protein_dimer.
- IBNtxA wikiPageWikiLink Μ-opioid_receptor.
- IBNtxA wikiPageWikiLinkText "IBNtxA".
- IBNtxA atcPrefix "none".
- IBNtxA c "27".
- IBNtxA chemspiderid "26617995".
- IBNtxA h "29".
- IBNtxA i "1".
- IBNtxA inchi "1".
- IBNtxA inchikey "FGAFDGWRFOJPRY-XGTKUTNFBD".
- IBNtxA iupacName "N-[-3--4a,9-dihydroxy-1,2,4,5,6,7,7a,13-octahydro-4,12-methanobenzofuro[3,2-e]isoquinoline-7-yl]-3-iodobenzamide".
- IBNtxA molecularWeight "572.434".
- IBNtxA n "2".
- IBNtxA o "4".
- IBNtxA pubchem "51003467".
- IBNtxA smiles "C1C[C@]2O".
- IBNtxA stdinchi "1".
- IBNtxA stdinchikey "FGAFDGWRFOJPRY-XGTKUTNFSA-N".
- IBNtxA width "220".
- IBNtxA wikiPageUsesTemplate Template:Analgesic-stub.
- IBNtxA wikiPageUsesTemplate Template:Drugbox.
- IBNtxA wikiPageUsesTemplate Template:Opioidergics.
- IBNtxA wikiPageUsesTemplate Template:Reflist.
- IBNtxA subject Category:Benzamides.
- IBNtxA subject Category:Mu-opioid_agonists.
- IBNtxA subject Category:Phenols.
- IBNtxA subject Category:Semisynthetic_opioids.
- IBNtxA hypernym Drug.
- IBNtxA type ChemicalSubstance.
- IBNtxA type Drug.
- IBNtxA type Group.
- IBNtxA type Agonist.
- IBNtxA type Alcohol.
- IBNtxA type Amide.
- IBNtxA type Chemical.
- IBNtxA type Drug.
- IBNtxA type Group.
- IBNtxA type Opioid.
- IBNtxA type ChemicalObject.
- IBNtxA type Thing.
- IBNtxA type Q8386.
- IBNtxA comment "IBNtxA, or 3-iodobenzoyl naltrexamine, is an atypical opioid analgesic drug derived from naltrexone. In animal studies it produces potent analgesic effects that are blocked by levallorphan and so appear to be μ-opioid mediated, but it fails to produce constipation or respiratory depression, and is neither rewarding or aversive in conditioned place preference protocols.".
- IBNtxA label "IBNtxA".
- IBNtxA sameAs Q4040988.
- IBNtxA sameAs m.0hrcnpd.
- IBNtxA sameAs IBNtxA.
- IBNtxA sameAs IBNtxA.
- IBNtxA sameAs IBNtxA.
- IBNtxA sameAs Q4040988.
- IBNtxA wasDerivedFrom IBNtxA?oldid=695177984.
- IBNtxA depiction IBNtxA_structure.png.
- IBNtxA isPrimaryTopicOf IBNtxA.