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- Hoffman_modulation_contrast_microscopy abstract "Hoffman modulation contrast microscopy (HMC microscopy) is an optical microscopy technique for enhancing the contrast in unstained biological specimens. The technique was invented by Robert Hoffman in 1975. Like differential interference contrast microscopy (DIC microscopy), contrast is increased by using components in the light path which convert phase gradients in the specimen into differences in light intensity that are rendered in an image that appears three-dimensional. The 3D appearance may be misleading, as a feature which appears to cast a shadow may not necessarily have a distinct physical geometry corresponding to the shadow. The technique is particularly suitable for optical sectioning at lower magnifications.An example of the use of HMC illumination is in in-vitro fertilisation, where under brightfield illumination the near-transparent oocyte is hard to see clearly.HMC systems typically consist of a condenser with a slit aperture, an objective with a slit aperture, and a polariser which is fitted between the condenser and the illumination source and is used to control the degree of contrast. The principle of HMC is used by a number of microscope manufacturers who have introduced their own variants of the technique, for example, ZEISS improved Hoffman Modulation Contrast (iHMC), Nikon advanced modulation contrast (NAMC), Olympus relief contrast (RC) and Leica's integrated hoffman modulation contrast (IMC).....".
- Hoffman_modulation_contrast_microscopy wikiPageExternalLink Tag.
- Hoffman_modulation_contrast_microscopy wikiPageID "27499844".
- Hoffman_modulation_contrast_microscopy wikiPageLength "2644".
- Hoffman_modulation_contrast_microscopy wikiPageOutDegree "8".
- Hoffman_modulation_contrast_microscopy wikiPageRevisionID "639913614".
- Hoffman_modulation_contrast_microscopy wikiPageWikiLink Category:Microscopy.
- Hoffman_modulation_contrast_microscopy wikiPageWikiLink Condenser_(microscope).
- Hoffman_modulation_contrast_microscopy wikiPageWikiLink Differential_interference_contrast_microscopy.
- Hoffman_modulation_contrast_microscopy wikiPageWikiLink In_vitro_fertilisation.
- Hoffman_modulation_contrast_microscopy wikiPageWikiLink Objective_(optics).
- Hoffman_modulation_contrast_microscopy wikiPageWikiLink Optical_microscope.
- Hoffman_modulation_contrast_microscopy wikiPageWikiLink Polarizer.
- Hoffman_modulation_contrast_microscopy wikiPageWikiLink File:Human-meniscus-cells-gruber-et-al-2008.tiff.
- Hoffman_modulation_contrast_microscopy wikiPageWikiLinkText "Hoffman modulation contrast microscopy".
- Hoffman_modulation_contrast_microscopy wikiPageUsesTemplate Template:Reflist.
- Hoffman_modulation_contrast_microscopy subject Category:Microscopy.
- Hoffman_modulation_contrast_microscopy hypernym Technique.
- Hoffman_modulation_contrast_microscopy type TopicalConcept.
- Hoffman_modulation_contrast_microscopy type Redirect.
- Hoffman_modulation_contrast_microscopy type Technique.
- Hoffman_modulation_contrast_microscopy comment "Hoffman modulation contrast microscopy (HMC microscopy) is an optical microscopy technique for enhancing the contrast in unstained biological specimens. The technique was invented by Robert Hoffman in 1975. Like differential interference contrast microscopy (DIC microscopy), contrast is increased by using components in the light path which convert phase gradients in the specimen into differences in light intensity that are rendered in an image that appears three-dimensional.".
- Hoffman_modulation_contrast_microscopy label "Hoffman modulation contrast microscopy".
- Hoffman_modulation_contrast_microscopy sameAs Q5876651.
- Hoffman_modulation_contrast_microscopy sameAs m.0c01nxl.
- Hoffman_modulation_contrast_microscopy sameAs Q5876651.
- Hoffman_modulation_contrast_microscopy wasDerivedFrom Hoffman_modulation_contrast_microscopy?oldid=639913614.
- Hoffman_modulation_contrast_microscopy isPrimaryTopicOf Hoffman_modulation_contrast_microscopy.