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- Heterocodeine abstract "Heterocodeine (6-methoxymorphine) is an opiate derivative, the 6-methyl ether of morphine, and a structural isomer of codeine; it is called \"hetero-\" because it is the reverse isomer of codeine. Heterocodeine was first synthesised in 1932 and first patented in 1935. It can be made from morphine by selective methylation. Codeine is the natural mono-methyl ether, but must be metabolized for activity (that is, it is a prodrug). In contrast the semi-synthetic mono-methyl ether, heterocodeine is a direct agonist. The 3,6 methyl di-ether of morphine is thebaine.Heterocodeine is 6 times more potent than morphine due to having a substitution at the 6-hydroxy position, in a similar manner to 6-acetylmorphine. The drug methyldihydromorphine (dihydroheterocodeine) is a derivative of heterocodeine. Like the morphine metabolite morphine-6-glucuronide, 6-position branches (esters or ethers) of morphine bind to the otherwise unagonized human mu receptor subtype mu-3 (or μ3); as well as the 6-acetylmorphine metabolite of heroin this includes heterocodeine.The relative strength of heterocodeine to codeine has been published as 50, 72, 81, 88, 93, 96, and 108 x.It is not mentioned specifically in the Controlled Substances Act 1970 but is a Schedule II controlled substance as an analogue of morphinan or morphine under the morphine structure rules of the Analogues Act; in other countries it is usually controlled as a strong opioid.Homocodeine is a synonym for pholcodine.".
- Heterocodeine atcPrefix "none".
- Heterocodeine casNumber "639-47-4".
- Heterocodeine iupacName "(5α,6α)-6-Methoxy-17-methyl-7,8-didehydro-4,5-epoxymorphinan-3-ol".
- Heterocodeine pubchem "5462505".
- Heterocodeine thumbnail Heterocodeine.svg?width=300.
- Heterocodeine wikiPageID "13487160".
- Heterocodeine wikiPageLength "4590".
- Heterocodeine wikiPageOutDegree "19".
- Heterocodeine wikiPageRevisionID "678912909".
- Heterocodeine wikiPageWikiLink 6-Monoacetylmorphine.
- Heterocodeine wikiPageWikiLink Category:Ethers.
- Heterocodeine wikiPageWikiLink Category:Morphinans.
- Heterocodeine wikiPageWikiLink Category:Mu-opioid_agonists.
- Heterocodeine wikiPageWikiLink Category:Phenols.
- Heterocodeine wikiPageWikiLink Category:Semisynthetic_opioids.
- Heterocodeine wikiPageWikiLink Chemical_structure.
- Heterocodeine wikiPageWikiLink Codeine.
- Heterocodeine wikiPageWikiLink Ether.
- Heterocodeine wikiPageWikiLink Isomer.
- Heterocodeine wikiPageWikiLink Methyl_group.
- Heterocodeine wikiPageWikiLink Methyldihydromorphine.
- Heterocodeine wikiPageWikiLink Morphinan.
- Heterocodeine wikiPageWikiLink Morphine.
- Heterocodeine wikiPageWikiLink Morphine-6-glucuronide.
- Heterocodeine wikiPageWikiLink Opiate.
- Heterocodeine wikiPageWikiLink Pholcodine.
- Heterocodeine wikiPageWikiLink Thebaine.
- Heterocodeine wikiPageWikiLinkText "Heterocodeine".
- Heterocodeine wikiPageWikiLinkText "heterocodeine".
- Heterocodeine atcPrefix "none".
- Heterocodeine c "18".
- Heterocodeine casNumber "639".
- Heterocodeine chembl "358043".
- Heterocodeine chemspiderid "4575432".
- Heterocodeine h "21".
- Heterocodeine inchi "1".
- Heterocodeine inchikey "FNAHUZTWOVOCTL-XSSYPUMDBX".
- Heterocodeine iupacName "-6".
- Heterocodeine legalUs "Schedule II".
- Heterocodeine molecularWeight "299.364".
- Heterocodeine n "1".
- Heterocodeine o "3".
- Heterocodeine pubchem "5462505".
- Heterocodeine smiles "O[C@H]2\C=C/[C@H]5[C@@H]4NC".
- Heterocodeine stdinchi "1".
- Heterocodeine stdinchikey "FNAHUZTWOVOCTL-XSSYPUMDSA-N".
- Heterocodeine synonyms "Heterocodeine, Morphine 6-methyl ether".
- Heterocodeine verifiedfields "changed".
- Heterocodeine verifiedrevid "461087666".
- Heterocodeine watchedfields "changed".
- Heterocodeine wikiPageUsesTemplate Template:Cascite.
- Heterocodeine wikiPageUsesTemplate Template:Chemspidercite.
- Heterocodeine wikiPageUsesTemplate Template:Drugbankcite.
- Heterocodeine wikiPageUsesTemplate Template:Drugbox.
- Heterocodeine wikiPageUsesTemplate Template:Ebicite.
- Heterocodeine wikiPageUsesTemplate Template:Opioidergics.
- Heterocodeine wikiPageUsesTemplate Template:Reflist.
- Heterocodeine wikiPageUsesTemplate Template:Stdinchicite.
- Heterocodeine subject Category:Ethers.
- Heterocodeine subject Category:Morphinans.
- Heterocodeine subject Category:Mu-opioid_agonists.
- Heterocodeine subject Category:Phenols.
- Heterocodeine subject Category:Semisynthetic_opioids.
- Heterocodeine hypernym Isomer.
- Heterocodeine type ChemicalCompound.
- Heterocodeine type ChemicalSubstance.
- Heterocodeine type Drug.
- Heterocodeine type Group.
- Heterocodeine type Agonist.
- Heterocodeine type Alcohol.
- Heterocodeine type Alkaloid.
- Heterocodeine type Analgesic.
- Heterocodeine type Chemical.
- Heterocodeine type Drug.
- Heterocodeine type Ether.
- Heterocodeine type Group.
- Heterocodeine type Heterocycle.
- Heterocodeine type Opioid.
- Heterocodeine type ChemicalObject.
- Heterocodeine type Thing.
- Heterocodeine type Q8386.
- Heterocodeine comment "Heterocodeine (6-methoxymorphine) is an opiate derivative, the 6-methyl ether of morphine, and a structural isomer of codeine; it is called \"hetero-\" because it is the reverse isomer of codeine. Heterocodeine was first synthesised in 1932 and first patented in 1935. It can be made from morphine by selective methylation. Codeine is the natural mono-methyl ether, but must be metabolized for activity (that is, it is a prodrug).".
- Heterocodeine label "Heterocodeine".
- Heterocodeine sameAs Q5746979.
- Heterocodeine sameAs m.03c6z2x.
- Heterocodeine sameAs Heterokodein.
- Heterocodeine sameAs Heterokodein.
- Heterocodeine sameAs Q5746979.
- Heterocodeine wasDerivedFrom Heterocodeine?oldid=678912909.
- Heterocodeine depiction Heterocodeine.svg.
- Heterocodeine isPrimaryTopicOf Heterocodeine.
