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- Hepatitis_B_virus_precore_mutant abstract "A precore mutant is a variety of hepatitis B virus that does not produce hepatitis B virus e antigen (HBeAg). These mutants are important because infections caused by these viruses are difficult to treat, and can cause infections of prolonged duration and with a higher risk of liver cirrhosis. The mutations are changes in DNA bases from guanine to adenine at base position 1896 (G1896A), and from cytosine to thymine at position 1858 (C1858T) in the precore region of the viral genome.The HBV has four genes: S, P, C, and X. The S gene codes for the \"major\" envelope protein (HBsAg). The largest gene is P. It codes for DNA polymerase. The C gene codes for HBeAg and HBcAg. The C gene has a precore and a core region. If translation is initiated at the precore region, the protein product is HBeAg. If translation begins with the core region, HBcAg is the protein product. HBeAg is a marker of HBV replication and infectivity. The precore region is not necessary for viral replication. Precore mutants can replicate. They are readily detectable by HBV DNA in serum, but hepatitis B e antigen (HbeAg) is absent. The X gene codes for HBxAg. The product of the X gene is hepatitis B x antigen (HBxAg). It may be involved in carcinogenesis.Basal core promoter mutants cause a reduction in HBeAg production. These mutations, A1762T and G1764A, occur in the basal core promoter region of the genome. The frequency of these mutations varies according to the HBV genotype.".
- Hepatitis_B_virus_precore_mutant thumbnail HBV_Genome.svg?width=300.
- Hepatitis_B_virus_precore_mutant wikiPageExternalLink 031504.asp.
- Hepatitis_B_virus_precore_mutant wikiPageExternalLink 1732124.
- Hepatitis_B_virus_precore_mutant wikiPageID "32135635".
- Hepatitis_B_virus_precore_mutant wikiPageLength "4129".
- Hepatitis_B_virus_precore_mutant wikiPageOutDegree "11".
- Hepatitis_B_virus_precore_mutant wikiPageRevisionID "678911838".
- Hepatitis_B_virus_precore_mutant wikiPageWikiLink Adenine.
- Hepatitis_B_virus_precore_mutant wikiPageWikiLink Carcinogenesis.
- Hepatitis_B_virus_precore_mutant wikiPageWikiLink Category:Hepatitis_B_virus.
- Hepatitis_B_virus_precore_mutant wikiPageWikiLink Cytosine.
- Hepatitis_B_virus_precore_mutant wikiPageWikiLink DNA_polymerase.
- Hepatitis_B_virus_precore_mutant wikiPageWikiLink Guanine.
- Hepatitis_B_virus_precore_mutant wikiPageWikiLink Hepatitis_B.
- Hepatitis_B_virus_precore_mutant wikiPageWikiLink Nucleobase.
- Hepatitis_B_virus_precore_mutant wikiPageWikiLink Thymine.
- Hepatitis_B_virus_precore_mutant wikiPageWikiLink Viral_envelope.
- Hepatitis_B_virus_precore_mutant wikiPageWikiLink File:HBV_Genome.svg.
- Hepatitis_B_virus_precore_mutant wikiPageWikiLinkText "Hepatitis B virus precore mutant".
- Hepatitis_B_virus_precore_mutant wikiPageUsesTemplate Template:Reflist.
- Hepatitis_B_virus_precore_mutant subject Category:Hepatitis_B_virus.
- Hepatitis_B_virus_precore_mutant hypernym Variety.
- Hepatitis_B_virus_precore_mutant type Grape.
- Hepatitis_B_virus_precore_mutant comment "A precore mutant is a variety of hepatitis B virus that does not produce hepatitis B virus e antigen (HBeAg). These mutants are important because infections caused by these viruses are difficult to treat, and can cause infections of prolonged duration and with a higher risk of liver cirrhosis.".
- Hepatitis_B_virus_precore_mutant label "Hepatitis B virus precore mutant".
- Hepatitis_B_virus_precore_mutant sameAs Q7239581.
- Hepatitis_B_virus_precore_mutant sameAs m.0gwyfc3.
- Hepatitis_B_virus_precore_mutant sameAs Q7239581.
- Hepatitis_B_virus_precore_mutant wasDerivedFrom Hepatitis_B_virus_precore_mutant?oldid=678911838.
- Hepatitis_B_virus_precore_mutant depiction HBV_Genome.svg.
- Hepatitis_B_virus_precore_mutant isPrimaryTopicOf Hepatitis_B_virus_precore_mutant.
