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- Hemopexin_family abstract "The hemopexin family is a family of evolutionarily related proteins. Hemopexin-like repeats occur in vitronectin and some matrix metalloproteinases family (matrixins). The HX repeats of some matrixins bind tissue inhibitor of metallopeptidases (TIMPs).Hemopexin (EC 3.2.1.35) is a serum glycoprotein that binds haem and transports it to the liver for breakdown and iron recovery, after which the free hemopexin returns to the circulation. Hemopexin prevents haem-mediated oxidative stress. Structurally hemopexin consists of two similar halves of approximately two hundred amino acid residues connected by a histidine-rich hinge region. Each half is itself formed by the repetition of a basic unit of some 35 to 45 residues. Hemopexin-like domains have been found in two other types of proteins, vitronectin, a cell adhesion and spreading factor found in plasma and tissues, and matrixins MMP-1, MMP-2, MMP-3, MMP-9, MMP-10, MMP-11, MMP-12, MMP-14, MMP-15 and MMP-16, members of the matrix metalloproteinase family that cleave extracellular matrix constituents. These zinc endopeptidases, which belong to MEROPS peptidase subfamily M10A, have a single hemopexin-like domain in their C-terminal section. It is suggested that the hemopexin domain facilitates binding to a variety of molecules and proteins, for example the HX repeats of some matrixins bind tissue inhibitor of metallopeptidases (TIMPs).".
- Hemopexin_family symbol "Hemopexin".
- Hemopexin_family wikiPageID "28960981".
- Hemopexin_family wikiPageLength "3976".
- Hemopexin_family wikiPageOutDegree "29".
- Hemopexin_family wikiPageRevisionID "607595621".
- Hemopexin_family wikiPageWikiLink Category:Single-pass_transmembrane_proteins.
- Hemopexin_family wikiPageWikiLink Hemopexin.
- Hemopexin_family wikiPageWikiLink MMP1.
- Hemopexin_family wikiPageWikiLink MMP10.
- Hemopexin_family wikiPageWikiLink MMP11.
- Hemopexin_family wikiPageWikiLink MMP14.
- Hemopexin_family wikiPageWikiLink MMP15.
- Hemopexin_family wikiPageWikiLink MMP16.
- Hemopexin_family wikiPageWikiLink MMP17.
- Hemopexin_family wikiPageWikiLink MMP19.
- Hemopexin_family wikiPageWikiLink MMP2.
- Hemopexin_family wikiPageWikiLink MMP20.
- Hemopexin_family wikiPageWikiLink MMP21.
- Hemopexin_family wikiPageWikiLink MMP24.
- Hemopexin_family wikiPageWikiLink MMP25.
- Hemopexin_family wikiPageWikiLink MMP27.
- Hemopexin_family wikiPageWikiLink MMP28.
- Hemopexin_family wikiPageWikiLink MMP3.
- Hemopexin_family wikiPageWikiLink MMP8.
- Hemopexin_family wikiPageWikiLink MMP9.
- Hemopexin_family wikiPageWikiLink Matrix_metallopeptidase_12.
- Hemopexin_family wikiPageWikiLink Matrix_metallopeptidase_13.
- Hemopexin_family wikiPageWikiLink Matrix_metalloproteinase.
- Hemopexin_family wikiPageWikiLink PRG4.
- Hemopexin_family wikiPageWikiLink Protein_family.
- Hemopexin_family wikiPageWikiLink Tissue_inhibitor_of_metalloproteinase.
- Hemopexin_family wikiPageWikiLink Vitronectin.
- Hemopexin_family wikiPageWikiLinkText "hemopexin family".
- Hemopexin_family interpro "IPR000585".
- Hemopexin_family name "Hemopexin".
- Hemopexin_family pdb ":328-372 B:328-372 :334-377 A:334-377 B:520-563 A:520-563 :520-563 :520-563 B:567-608 A:567-608 :306-349 A:306-349 A:306-349".
- Hemopexin_family pfam "PF00045".
- Hemopexin_family prosite "PDOC00023".
- Hemopexin_family scop "1".
- Hemopexin_family smart "HX".
- Hemopexin_family symbol "Hemopexin".
- Hemopexin_family wikiPageUsesTemplate Template:EC_number.
- Hemopexin_family wikiPageUsesTemplate Template:InterPro_content.
- Hemopexin_family wikiPageUsesTemplate Template:Membrane-protein-stub.
- Hemopexin_family wikiPageUsesTemplate Template:PDB3.
- Hemopexin_family wikiPageUsesTemplate Template:Pfam_box.
- Hemopexin_family wikiPageUsesTemplate Template:Reflist.
- Hemopexin_family subject Category:Single-pass_transmembrane_proteins.
- Hemopexin_family hypernym Family.
- Hemopexin_family type Biomolecule.
- Hemopexin_family type Protein.
- Hemopexin_family type Thing.
- Hemopexin_family type Q206229.
- Hemopexin_family type Q8054.
- Hemopexin_family comment "The hemopexin family is a family of evolutionarily related proteins. Hemopexin-like repeats occur in vitronectin and some matrix metalloproteinases family (matrixins). The HX repeats of some matrixins bind tissue inhibitor of metallopeptidases (TIMPs).Hemopexin (EC 3.2.1.35) is a serum glycoprotein that binds haem and transports it to the liver for breakdown and iron recovery, after which the free hemopexin returns to the circulation. Hemopexin prevents haem-mediated oxidative stress.".
- Hemopexin_family label "Hemopexin family".
- Hemopexin_family sameAs Q5712519.
- Hemopexin_family sameAs m.0dgrf21.
- Hemopexin_family sameAs Q5712519.
- Hemopexin_family wasDerivedFrom Hemopexin_family?oldid=607595621.
- Hemopexin_family isPrimaryTopicOf Hemopexin_family.