Matches in DBpedia 2016-04 for { <http://dbpedia.org/resource/Griffithsin> ?p ?o }
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- Griffithsin abstract "Griffithsin is a protein isolated from the red algae Griffithsia. It has a 121-amino acid sequence which exhibits a Jacalin-like lectin fold. Several structures of this protein have been solved by X-ray crystallography and deposited in the PDB. It has been shown in vitro to be a highly potent HIV entry inhibitor. It is currently being investigated as a potential microbicide for use in the prevention of the transmission of HIV. Griffithsin shows a broad spectrum ability to bind to the glycoproteins of other viruses, such as the coronavirus. Griffithsin's three identical carbohydrate domains bind to specific oligosaccharides on the envelope of viral glycoproteins. This was demonstrated by in vitro and in vivo studies. For instance, it was shown that griffithsin binds to the SARS-CoV spike glycoprotein to inhibit entry of the SARS virus and thus inhibit infection. A 2014 study showed griffithsin to also possess useful antiviral activity against Ebolavirus.As reported in March 2009, Kenneth Palmer and coworkers modified the tobacco mosaic virus to incorporate the griffithsin gene and infected more than 9,300 tobacco plants. They were able to extract enough griffithsin to produce about 100,000 HIV microbicide doses from the leaves.".
- Griffithsin thumbnail 3ll2.png?width=300.
- Griffithsin wikiPageExternalLink searchResults.html?display=both&term=P84801.
- Griffithsin wikiPageID "14713488".
- Griffithsin wikiPageLength "5186".
- Griffithsin wikiPageOutDegree "24".
- Griffithsin wikiPageRevisionID "699102863".
- Griffithsin wikiPageWikiLink Category:Entry_inhibitors.
- Griffithsin wikiPageWikiLink Category:Proteins.
- Griffithsin wikiPageWikiLink Coronavirus.
- Griffithsin wikiPageWikiLink Ebolavirus.
- Griffithsin wikiPageWikiLink Entry_inhibitor.
- Griffithsin wikiPageWikiLink Glycoprotein.
- Griffithsin wikiPageWikiLink Griffithsia.
- Griffithsin wikiPageWikiLink HIV.
- Griffithsin wikiPageWikiLink In_vitro.
- Griffithsin wikiPageWikiLink In_vivo.
- Griffithsin wikiPageWikiLink Jacalin-like_lectin_domain.
- Griffithsin wikiPageWikiLink Microbicide.
- Griffithsin wikiPageWikiLink Peptide_sequence.
- Griffithsin wikiPageWikiLink Protein.
- Griffithsin wikiPageWikiLink Protein_Data_Bank.
- Griffithsin wikiPageWikiLink Red_algae.
- Griffithsin wikiPageWikiLink Severe_acute_respiratory_syndrome.
- Griffithsin wikiPageWikiLink Tobacco.
- Griffithsin wikiPageWikiLink Tobacco_mosaic_virus.
- Griffithsin wikiPageWikiLink X-ray_crystallography.
- Griffithsin wikiPageWikiLinkText "Griffithsin".
- Griffithsin wikiPageWikiLinkText "griffithsin".
- Griffithsin caption "Griffithsin in complex with a high-mannose branched carbohydrate. PDB".
- Griffithsin name "Griffithsin".
- Griffithsin organism "Griffithsia sp.".
- Griffithsin pdb "3".
- Griffithsin pdbSupplemental searchResults.html?display=both&term=P84801.
- Griffithsin symbol "GRTF".
- Griffithsin taxid "373036".
- Griffithsin uniprot "P84801".
- Griffithsin wikiPageUsesTemplate Template:Antiinfective-drug-stub.
- Griffithsin wikiPageUsesTemplate Template:Biochem-stub.
- Griffithsin wikiPageUsesTemplate Template:Expert-subject.
- Griffithsin wikiPageUsesTemplate Template:HIVpharm.
- Griffithsin wikiPageUsesTemplate Template:Infobox_nonhuman_protein.
- Griffithsin wikiPageUsesTemplate Template:PDBe.
- Griffithsin wikiPageUsesTemplate Template:Reflist.
- Griffithsin subject Category:Entry_inhibitors.
- Griffithsin subject Category:Proteins.
- Griffithsin hypernym Protein.
- Griffithsin type Biomolecule.
- Griffithsin type Drug.
- Griffithsin type Protein.
- Griffithsin type Biomolecule.
- Griffithsin type Drug.
- Griffithsin type Inhibitor.
- Griffithsin type Nutrient.
- Griffithsin comment "Griffithsin is a protein isolated from the red algae Griffithsia. It has a 121-amino acid sequence which exhibits a Jacalin-like lectin fold. Several structures of this protein have been solved by X-ray crystallography and deposited in the PDB. It has been shown in vitro to be a highly potent HIV entry inhibitor. It is currently being investigated as a potential microbicide for use in the prevention of the transmission of HIV.".
- Griffithsin label "Griffithsin".
- Griffithsin sameAs Q5608941.
- Griffithsin sameAs m.03gv0j9.
- Griffithsin sameAs Q5608941.
- Griffithsin wasDerivedFrom Griffithsin?oldid=699102863.
- Griffithsin depiction 3ll2.png.
- Griffithsin isPrimaryTopicOf Griffithsin.
