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- Giant-cell_fibroma abstract "Giant-cell fibroma is a type of fibroma not associated with trauma or irritation. It can occur at any age and on a mucous membrane surface. The most common oral locations are on the gingiva of the mandible, tongue, and palate. It is a localized reactive proliferation of fibrous connective tissue.Giant-cell fibroma (GCF) is a benign non-neoplastic lesion first described by Weathers and Callihan (1974). It occurs in the first three decades of life and predominates in females (Houston, 1982; Bakos, 1992). Clinically, the GCF presents as an asymptomatic, papillary and pedunculated lesion. The most predominant location is the mandibular gingiva (Houston, 1982; Bakos, 1992). Histologically, the GCF is distinctive, consisting of fibrous connective tissue without inflammation and covered with stratified squamous hyperplastic epithelium. The most characteristic histological feature is the presence of large spindle-shaped and stellate-shaped mononuclear cells and multinucleated cells. These cells occur in a variety of lesions, such as the fibrous papule of the nose, ungual fibroma, acral fibrokeratoma, acral angiofibroma and desmoplastic fibroblastoma (Swan, 1988; Pitt et al., 1993; Karabela-Bouropoulou et al., 1999; Jang et al., 1999). Despite many studies, the nature of the stellated multinucleate and mononuclear cell is not clear (Weathers and Campbell, 1974; Regezi et al., 1987; Odell et al., 1994; Magnusson and Rasmusson, 1995).".
- Giant-cell_fibroma wikiPageID "7454361".
- Giant-cell_fibroma wikiPageLength "1895".
- Giant-cell_fibroma wikiPageOutDegree "9".
- Giant-cell_fibroma wikiPageRevisionID "641906040".
- Giant-cell_fibroma wikiPageWikiLink Category:Oral_neoplasia.
- Giant-cell_fibroma wikiPageWikiLink Connective_tissue.
- Giant-cell_fibroma wikiPageWikiLink Fibroma.
- Giant-cell_fibroma wikiPageWikiLink Gingiva.
- Giant-cell_fibroma wikiPageWikiLink Mandible.
- Giant-cell_fibroma wikiPageWikiLink Mucous_membrane.
- Giant-cell_fibroma wikiPageWikiLink Multinucleate.
- Giant-cell_fibroma wikiPageWikiLink Palate.
- Giant-cell_fibroma wikiPageWikiLink Tongue.
- Giant-cell_fibroma wikiPageWikiLinkText "Giant-cell fibroma".
- Giant-cell_fibroma wikiPageUsesTemplate Template:Disease-stub.
- Giant-cell_fibroma wikiPageUsesTemplate Template:Reflist.
- Giant-cell_fibroma subject Category:Oral_neoplasia.
- Giant-cell_fibroma hypernym Fibroma.
- Giant-cell_fibroma type Disease.
- Giant-cell_fibroma type Thing.
- Giant-cell_fibroma type Q12136.
- Giant-cell_fibroma comment "Giant-cell fibroma is a type of fibroma not associated with trauma or irritation. It can occur at any age and on a mucous membrane surface. The most common oral locations are on the gingiva of the mandible, tongue, and palate. It is a localized reactive proliferation of fibrous connective tissue.Giant-cell fibroma (GCF) is a benign non-neoplastic lesion first described by Weathers and Callihan (1974).".
- Giant-cell_fibroma label "Giant-cell fibroma".
- Giant-cell_fibroma sameAs Q5558339.
- Giant-cell_fibroma sameAs m.02627x6.
- Giant-cell_fibroma sameAs Q5558339.
- Giant-cell_fibroma wasDerivedFrom Giant-cell_fibroma?oldid=641906040.
- Giant-cell_fibroma isPrimaryTopicOf Giant-cell_fibroma.