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- Gene_co-expression_network abstract "A gene co-expression network (GCN) is an undirected graph, where each node corresponds to a gene, and a pair of nodes is connected with an edge if there is a significant co-expression relationship between them. Having gene expression profiles of a number of genes for several samples or experimental conditions, a gene co-expression network can be constructed by looking for pairs of genes which show a similar expression pattern across samples, since the transcript levels of two co-expressed genes rise and fall together across samples. Gene co-expression networks are of biological interest since co-expressed genes are controlled by the same transcriptional regulatory program, functionally related, or members of the same pathway or protein complex.The direction and type of co-expression relationships are not determined in gene co-expression networks; whereas in a gene regulatory network (GRN) a directed edge connects two genes, representing a biochemical process such as a reaction, transformation, interaction, activation or inhibition. Compared to a GRN, a GCN does not attempt to infer the causality relationships between genes and in a GCN the edges represent only a correlation or dependency relationship among genes. Modules or the highly connected subgraphs in gene co-expression networks correspond to clusters of genes that have a similar function or involve in a common biological process which causes many interactions among themselves.Gene co-expression networks are usually constructed using datasets generated by high-throughput gene expression profiling technologies such as Microarray or RNA-Seq.".
- Gene_co-expression_network thumbnail Gene_co-expression_network_with_7221_genes_for_18_gastric_cancer_patients.png?width=300.
- Gene_co-expression_network wikiPageExternalLink coexpression.
- Gene_co-expression_network wikiPageID "43769798".
- Gene_co-expression_network wikiPageLength "15223".
- Gene_co-expression_network wikiPageOutDegree "28".
- Gene_co-expression_network wikiPageRevisionID "702592644".
- Gene_co-expression_network wikiPageWikiLink Biological_network.
- Gene_co-expression_network wikiPageWikiLink Biological_network_inference.
- Gene_co-expression_network wikiPageWikiLink Category:Bioinformatics.
- Gene_co-expression_network wikiPageWikiLink Category:Computational_biology.
- Gene_co-expression_network wikiPageWikiLink Category:Systems_biology.
- Gene_co-expression_network wikiPageWikiLink Clustering_coefficient.
- Gene_co-expression_network wikiPageWikiLink Euclidean_distance.
- Gene_co-expression_network wikiPageWikiLink Fisher_transformation.
- Gene_co-expression_network wikiPageWikiLink Gene.
- Gene_co-expression_network wikiPageWikiLink Gene_expression_profiling.
- Gene_co-expression_network wikiPageWikiLink Gene_regulatory_network.
- Gene_co-expression_network wikiPageWikiLink Graph_(discrete_mathematics).
- Gene_co-expression_network wikiPageWikiLink Microarray.
- Gene_co-expression_network wikiPageWikiLink Mutual_information.
- Gene_co-expression_network wikiPageWikiLink P-value.
- Gene_co-expression_network wikiPageWikiLink Partial_correlation.
- Gene_co-expression_network wikiPageWikiLink Pearson_product-moment_correlation_coefficient.
- Gene_co-expression_network wikiPageWikiLink RNA-Seq.
- Gene_co-expression_network wikiPageWikiLink Regression_analysis.
- Gene_co-expression_network wikiPageWikiLink Scale-free_network.
- Gene_co-expression_network wikiPageWikiLink Spearmans_rank_correlation_coefficient.
- Gene_co-expression_network wikiPageWikiLink Standard_score.
- Gene_co-expression_network wikiPageWikiLink Weighted_correlation_network_analysis.
- Gene_co-expression_network wikiPageWikiLink File:Gene_co-expression_network_construction_steps.png.
- Gene_co-expression_network wikiPageWikiLink File:Gene_co-expression_network_with_7221_genes_for_18_gastric_cancer_patients.png.
- Gene_co-expression_network wikiPageWikiLink File:Gene_co-expression_vs_regulation.png.
- Gene_co-expression_network wikiPageWikiLinkText "Gene co-expression network".
- Gene_co-expression_network wikiPageWikiLinkText "coexpression".
- Gene_co-expression_network wikiPageWikiLinkText "gene co-expression network".
- Gene_co-expression_network wikiPageUsesTemplate Template:Reflist.
- Gene_co-expression_network subject Category:Bioinformatics.
- Gene_co-expression_network subject Category:Computational_biology.
- Gene_co-expression_network subject Category:Systems_biology.
- Gene_co-expression_network hypernym Graph.
- Gene_co-expression_network type Software.
- Gene_co-expression_network comment "A gene co-expression network (GCN) is an undirected graph, where each node corresponds to a gene, and a pair of nodes is connected with an edge if there is a significant co-expression relationship between them.".
- Gene_co-expression_network label "Gene co-expression network".
- Gene_co-expression_network sameAs Q18207329.
- Gene_co-expression_network sameAs Réseaux_de_co-expression_de_gènes.
- Gene_co-expression_network sameAs m.011sn3d4.
- Gene_co-expression_network sameAs Q18207329.
- Gene_co-expression_network wasDerivedFrom Gene_co-expression_network?oldid=702592644.
- Gene_co-expression_network depiction Gene_co-expression_network_with_7221_genes_for_18_gastric_cancer_patients.png.
- Gene_co-expression_network isPrimaryTopicOf Gene_co-expression_network.
