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- GDP-fucose_protein_O-fucosyltransferase_1 abstract "GDP-fucose protein O-fucosyltransferase 1 (POFUT1) is an enzyme responsible for adding fucose sugars in O linkage to serine or threonine residues between the second and third conserved cysteines in EGF-like repeats on the Notch protein. The protein is an inverting glycosyltransferase, which means that the enzyme uses GDP-β-L-fucose as a donor substrate and transfers the fucose in O linkage to the protein producing fucose-α-O-serine/threonine.When the gene for POFUT1 is knocked out, or the expression is decreased to very low levels, all Notch signaling is destroyed, which means that fucose on Notch is essential for Notch function. Why this is the case is not yet well understood.Almost all glycosyltransferases reside in the Golgi apparatus. However, POFUT1 as well as the related enzyme POFUT2 have recently been shown to reside in the endoplasmic reticulum.".
- GDP-fucose_protein_O-fucosyltransferase_1 arm "q".
- GDP-fucose_protein_O-fucosyltransferase_1 band "11".
- GDP-fucose_protein_O-fucosyltransferase_1 chromosome "20".
- GDP-fucose_protein_O-fucosyltransferase_1 ecNumber "2.4.1.221".
- GDP-fucose_protein_O-fucosyltransferase_1 entrezgene "23509".
- GDP-fucose_protein_O-fucosyltransferase_1 hgncid "14988".
- GDP-fucose_protein_O-fucosyltransferase_1 omim "607491".
- GDP-fucose_protein_O-fucosyltransferase_1 refseq "NM_172236".
- GDP-fucose_protein_O-fucosyltransferase_1 symbol "POFUT1".
- GDP-fucose_protein_O-fucosyltransferase_1 uniprot "Q9H488".
- GDP-fucose_protein_O-fucosyltransferase_1 wikiPageID "3444065".
- GDP-fucose_protein_O-fucosyltransferase_1 wikiPageLength "1495".
- GDP-fucose_protein_O-fucosyltransferase_1 wikiPageOutDegree "14".
- GDP-fucose_protein_O-fucosyltransferase_1 wikiPageRevisionID "699072109".
- GDP-fucose_protein_O-fucosyltransferase_1 wikiPageWikiLink Category:EC_2.4.1.
- GDP-fucose_protein_O-fucosyltransferase_1 wikiPageWikiLink Category:Transferases.
- GDP-fucose_protein_O-fucosyltransferase_1 wikiPageWikiLink Endoplasmic_reticulum.
- GDP-fucose_protein_O-fucosyltransferase_1 wikiPageWikiLink Enzyme.
- GDP-fucose_protein_O-fucosyltransferase_1 wikiPageWikiLink Epidermal_growth_factor.
- GDP-fucose_protein_O-fucosyltransferase_1 wikiPageWikiLink Fucose.
- GDP-fucose_protein_O-fucosyltransferase_1 wikiPageWikiLink GDP-fucose_protein_O-fucosyltransferase_2.
- GDP-fucose_protein_O-fucosyltransferase_1 wikiPageWikiLink Glycosyltransferase.
- GDP-fucose_protein_O-fucosyltransferase_1 wikiPageWikiLink Golgi_apparatus.
- GDP-fucose_protein_O-fucosyltransferase_1 wikiPageWikiLink Notch_proteins.
- GDP-fucose_protein_O-fucosyltransferase_1 wikiPageWikiLink Notch_signaling_pathway.
- GDP-fucose_protein_O-fucosyltransferase_1 wikiPageWikiLink Serine.
- GDP-fucose_protein_O-fucosyltransferase_1 wikiPageWikiLink Threonine.
- GDP-fucose_protein_O-fucosyltransferase_1 wikiPageWikiLinkText "''O''-fucosyltransferase".
- GDP-fucose_protein_O-fucosyltransferase_1 wikiPageWikiLinkText "GDP-fucose protein O-fucosyltransferase 1".
- GDP-fucose_protein_O-fucosyltransferase_1 arm "q".
- GDP-fucose_protein_O-fucosyltransferase_1 band "11".
- GDP-fucose_protein_O-fucosyltransferase_1 chromosome "20".
- GDP-fucose_protein_O-fucosyltransferase_1 ecnumber "2.4".
- GDP-fucose_protein_O-fucosyltransferase_1 entrezgene "23509".
- GDP-fucose_protein_O-fucosyltransferase_1 hgncid "14988".
- GDP-fucose_protein_O-fucosyltransferase_1 name "protein O-fucosyltransferase 1".
- GDP-fucose_protein_O-fucosyltransferase_1 omim "607491".
- GDP-fucose_protein_O-fucosyltransferase_1 refseq "NM_172236".
- GDP-fucose_protein_O-fucosyltransferase_1 symbol "POFUT1".
- GDP-fucose_protein_O-fucosyltransferase_1 uniprot "Q9H488".
- GDP-fucose_protein_O-fucosyltransferase_1 wikiPageUsesTemplate Template:Enzymes.
- GDP-fucose_protein_O-fucosyltransferase_1 wikiPageUsesTemplate Template:Glycosyltransferases.
- GDP-fucose_protein_O-fucosyltransferase_1 wikiPageUsesTemplate Template:Infobox_protein.
- GDP-fucose_protein_O-fucosyltransferase_1 wikiPageUsesTemplate Template:MeshName.
- GDP-fucose_protein_O-fucosyltransferase_1 wikiPageUsesTemplate Template:Portal_bar.
- GDP-fucose_protein_O-fucosyltransferase_1 subject Category:EC_2.4.1.
- GDP-fucose_protein_O-fucosyltransferase_1 subject Category:Transferases.
- GDP-fucose_protein_O-fucosyltransferase_1 hypernym Enzyme.
- GDP-fucose_protein_O-fucosyltransferase_1 type Biomolecule.
- GDP-fucose_protein_O-fucosyltransferase_1 type Protein.
- GDP-fucose_protein_O-fucosyltransferase_1 type Redirect.
- GDP-fucose_protein_O-fucosyltransferase_1 type Thing.
- GDP-fucose_protein_O-fucosyltransferase_1 type Q206229.
- GDP-fucose_protein_O-fucosyltransferase_1 type Q8054.
- GDP-fucose_protein_O-fucosyltransferase_1 comment "GDP-fucose protein O-fucosyltransferase 1 (POFUT1) is an enzyme responsible for adding fucose sugars in O linkage to serine or threonine residues between the second and third conserved cysteines in EGF-like repeats on the Notch protein.".
- GDP-fucose_protein_O-fucosyltransferase_1 label "GDP-fucose protein O-fucosyltransferase 1".
- GDP-fucose_protein_O-fucosyltransferase_1 sameAs Q18037225.
- GDP-fucose_protein_O-fucosyltransferase_1 sameAs m.09cr7_.
- GDP-fucose_protein_O-fucosyltransferase_1 sameAs Q18037225.
- GDP-fucose_protein_O-fucosyltransferase_1 wasDerivedFrom GDP-fucose_protein_O-fucosyltransferase_1?oldid=699072109.
- GDP-fucose_protein_O-fucosyltransferase_1 isPrimaryTopicOf GDP-fucose_protein_O-fucosyltransferase_1.
- GDP-fucose_protein_O-fucosyltransferase_1 name "protein O-fucosyltransferase 1".