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- Flip-flop_kinetics abstract "In pharmacokinetics, flip-flop phenomenon happens when a drug is released at a sustained rate instead of immediate release, such as sustained-release formulation vs. immediate-release formulation (tablet, IV).In flip-flop kinetics, ka (absorption constant) is much slower than ke (elimination constant). This apparent difference shift the slope of logCp vs time curve in which now the apparent part of ke looks much smaller than it is if the drug is administered intravenously or by immediate-release formulation. The part of downward curve becomes a reflection of actual ka while the upward part of the curve is the actual representation of ke. That \"flip-flop\" part of curve is the so-called flip-flop kinetics.The application of flip-flop kinetics is very important in the development of sustained-release and controlled-release formulation in pharmaceutical manufacturing.".
- Flip-flop_kinetics wikiPageExternalLink flip-flop.htm.
- Flip-flop_kinetics wikiPageID "13589014".
- Flip-flop_kinetics wikiPageLength "1767".
- Flip-flop_kinetics wikiPageOutDegree "9".
- Flip-flop_kinetics wikiPageRevisionID "601779548".
- Flip-flop_kinetics wikiPageWikiLink Category:Pharmacokinetics.
- Flip-flop_kinetics wikiPageWikiLink Controlled-release.
- Flip-flop_kinetics wikiPageWikiLink Elimination_constant.
- Flip-flop_kinetics wikiPageWikiLink Immediate-release.
- Flip-flop_kinetics wikiPageWikiLink Intravenous_therapy.
- Flip-flop_kinetics wikiPageWikiLink Molar_attenuation_coefficient.
- Flip-flop_kinetics wikiPageWikiLink Pharmacokinetics.
- Flip-flop_kinetics wikiPageWikiLink Tablet_(pharmacy).
- Flip-flop_kinetics wikiPageWikiLink Time_release_technology.
- Flip-flop_kinetics wikiPageWikiLinkText "Flip-flop kinetics".
- Flip-flop_kinetics wikiPageUsesTemplate Template:Reflist.
- Flip-flop_kinetics subject Category:Pharmacokinetics.
- Flip-flop_kinetics type Pharmaceutic.
- Flip-flop_kinetics comment "In pharmacokinetics, flip-flop phenomenon happens when a drug is released at a sustained rate instead of immediate release, such as sustained-release formulation vs. immediate-release formulation (tablet, IV).In flip-flop kinetics, ka (absorption constant) is much slower than ke (elimination constant).".
- Flip-flop_kinetics label "Flip-flop kinetics".
- Flip-flop_kinetics sameAs Q5459639.
- Flip-flop_kinetics sameAs m.03cb7_v.
- Flip-flop_kinetics sameAs Q5459639.
- Flip-flop_kinetics wasDerivedFrom Flip-flop_kinetics?oldid=601779548.
- Flip-flop_kinetics isPrimaryTopicOf Flip-flop_kinetics.