DBpedia – Linked Data Fragments

Matches in DBpedia 2016-04 for { <http://dbpedia.org/resource/Epirubicin> ?p ?o }

• Epirubicin abstract "Epirubicin is an anthracycline drug used for chemotherapy. It can be used in combination with other medications to treat breast cancer in patients who have had surgery to remove the tumor. It is marketed by Pfizer under the trade name Ellence in the US and Pharmorubicin or Epirubicin Ebewe elsewhere. Similarly to other anthracyclines, epirubicin acts by intercalating DNA strands.Intercalation results in complex formation which inhibits DNA and RNA synthesis. It also triggers DNA cleavage by topoisomerase II, resulting in mechanisms that lead to cell death. Binding to cell membranes and plasma proteins may be involved in the compound's cytotoxic effects. Epirubicin also generates free radicals that cause cell and DNA damage.Epirubicin is favoured over doxorubicin, the most popular anthracycline, in some chemotherapy regimens as it appears to cause fewer side-effects. Epirubicin has a different spatial orientation of the hydroxyl group at the 4' carbon of the sugar - it has the opposite chirality - which may account for its faster elimination and reduced toxicity. Epirubicin is primarily used against breast and ovarian cancer, gastric cancer, lung cancer and lymphomas.".
• Epirubicin atcPrefix "L01".
• Epirubicin atcSuffix "DB03".
• Epirubicin casNumber "56420-45-2".
• Epirubicin chEBI "47898".
• Epirubicin drugbank "DB00445".
• Epirubicin fdaUniiCode "3Z8479ZZ5X".
• Epirubicin iupacName "(8R,10S)-10-((2S,4S,5R,6S)-4-amino-5-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)-6,8,11-trihydroxy-8-(2-hydroxyacetyl)-1-methoxy-7,8,9,10-tetrahydrotetracene-5,12-dione".
• Epirubicin pubchem "41867".
• Epirubicin thumbnail Epirubicin.png?width=300.
• Epirubicin wikiPageExternalLink Epirubicin.htm.
• Epirubicin wikiPageExternalLink description.html.
• Epirubicin wikiPageID "2150359".
• Epirubicin wikiPageLength "5045".
• Epirubicin wikiPageOutDegree "25".
• Epirubicin wikiPageRevisionID "705470521".
• Epirubicin wikiPageWikiLink Anthracycline.
• Epirubicin wikiPageWikiLink Australia.
• Epirubicin wikiPageWikiLink Category:Anthracyclines.
• Epirubicin wikiPageWikiLink Category:Pfizer_products.
• Epirubicin wikiPageWikiLink Category:Topoisomerase_inhibitors.
• Epirubicin wikiPageWikiLink Chemotherapy.
• Epirubicin wikiPageWikiLink Chemotherapy_regimen.
• Epirubicin wikiPageWikiLink DNA.
• Epirubicin wikiPageWikiLink Doxorubicin.
• Epirubicin wikiPageWikiLink Food_and_Drug_Administration.
• Epirubicin wikiPageWikiLink Glucuronidation.
• Epirubicin wikiPageWikiLink Intercalation_(chemistry).
• Epirubicin wikiPageWikiLink Intravenous_therapy.
• Epirubicin wikiPageWikiLink Kidney.
• Epirubicin wikiPageWikiLink Liver.
• Epirubicin wikiPageWikiLink Pfizer.
• Epirubicin wikiPageWikiLink Pharmaceutical_drug.
• Epirubicin wikiPageWikiLink Pharmacia.
• Epirubicin wikiPageWikiLink Prescription_drug.
• Epirubicin wikiPageWikiLink Radical_(chemistry).
• Epirubicin wikiPageWikiLink Redox.
• Epirubicin wikiPageWikiLink Type_II_topoisomerase.
• Epirubicin wikiPageWikiLink United_Kingdom.
• Epirubicin wikiPageWikiLink United_States.
• Epirubicin wikiPageWikiLink Upjohn.
• Epirubicin wikiPageWikiLinkText "Epirubicin".
• Epirubicin wikiPageWikiLinkText "epirubicin".
• Epirubicin atcPrefix "L01".
• Epirubicin atcSuffix "DB03".
• Epirubicin bioavailability "NA".
• Epirubicin c "27".
• Epirubicin casNumber "56420".
• Epirubicin chebi "47898".
• Epirubicin chembl "417".
• Epirubicin chemspiderid "38201".
• Epirubicin drugbank "DB00445".
• Epirubicin excretion "Biliary and renal".
• Epirubicin h "29".
• Epirubicin image "Epirubicin ball-and-stick.png".
• Epirubicin inchi "1".
• Epirubicin inchikey "AOJJSUZBOXZQNB-VTZDEGQIBI".
• Epirubicin iupacName "-10".
• Epirubicin kegg "D07901".
• Epirubicin legalStatus "℞-only , POM".
• Epirubicin medlineplus "a603003".
• Epirubicin metabolism "Hepatic glucuronidation and oxidation".
• Epirubicin molecularWeight "543.519".
• Epirubicin n "1".
• Epirubicin o "11".
• Epirubicin pregnancyCategory "D".
• Epirubicin proteinBound "77.0".
• Epirubicin pubchem "41867".
• Epirubicin routesOfAdministration Intravenous_therapy.
• Epirubicin smiles "O=C2c1cc5cC[C@@]C[C@@H]5O[C@@H]4O[C@H]C".
• Epirubicin stdinchi "1".
• Epirubicin stdinchikey "AOJJSUZBOXZQNB-VTZDEGQISA-N".
• Epirubicin tradename "Ellence".
• Epirubicin unii "3".
• Epirubicin verifiedrevid "461094075".
• Epirubicin watchedfields "changed".
• Epirubicin wikiPageUsesTemplate Template:Cascite.
• Epirubicin wikiPageUsesTemplate Template:Chemotherapeutic_agents.
• Epirubicin wikiPageUsesTemplate Template:Chemspidercite.
• Epirubicin wikiPageUsesTemplate Template:Drugbankcite.
• Epirubicin wikiPageUsesTemplate Template:Drugbox.
• Epirubicin wikiPageUsesTemplate Template:Drugs.com.
• Epirubicin wikiPageUsesTemplate Template:Ebicite.
• Epirubicin wikiPageUsesTemplate Template:Fdacite.
• Epirubicin wikiPageUsesTemplate Template:Keggcite.
• Epirubicin wikiPageUsesTemplate Template:Reflist.
• Epirubicin wikiPageUsesTemplate Template:Stdinchicite.
• Epirubicin subject Category:Anthracyclines.
• Epirubicin subject Category:Pfizer_products.
• Epirubicin subject Category:Topoisomerase_inhibitors.
• Epirubicin hypernym Drug.
• Epirubicin type ChemicalSubstance.
• Epirubicin type Company.
• Epirubicin type Drug.
• Epirubicin type Company.
• Epirubicin type Inhibitor.
• Epirubicin type Redirect.
• Epirubicin type ChemicalObject.
• Epirubicin type Thing.
• Epirubicin type Q8386.

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