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Matches in DBpedia 2016-04 for { <http://dbpedia.org/resource/Discovery_and_development_of_cyclooxygenase_2_inhibitors> ?p ?o }

• Discovery_and_development_of_cyclooxygenase_2_inhibitors abstract "Cyclooxygenases are enzymes that take part in a complex biosynthetic cascade that results in the conversion of polyunsaturated fatty acids to prostaglandins and thromboxane(s).Their main role is to catalyze the transformation of arachidonic acid into the intermediate prostaglandin H2, which is the procursor of a variety of prostanoids with diverse and potent biological actions.Cyclooxygenases have two main isoforms that are called COX-1 and COX-2 (as well as a COX-3). COX-1 is responsible for the synthesis of prostaglandin and thromboxane in many types of cells, including the gastro-intestinal tract and blood platelets. COX-2 plays a major role in prostaglandin biosynthesis in inflammatory cells and in the central nervous system. Prostaglandin synthesis in these sites is a key factor in the development of inflammation and hyperalgesia.COX-2 inhibitors have analgesic and anti-inflammatory activity by blocking the transformation of arachidonic acid into prostaglandin H2 selectively.".
• Discovery_and_development_of_cyclooxygenase_2_inhibitors thumbnail DuP-697.png?width=300.
• Discovery_and_development_of_cyclooxygenase_2_inhibitors wikiPageID "20187427".
• Discovery_and_development_of_cyclooxygenase_2_inhibitors wikiPageLength "32289".
• Discovery_and_development_of_cyclooxygenase_2_inhibitors wikiPageOutDegree "110".
• Discovery_and_development_of_cyclooxygenase_2_inhibitors wikiPageRevisionID "669726307".
• Discovery_and_development_of_cyclooxygenase_2_inhibitors wikiPageWikiLink Absorption_(pharmacokinetics).
• Discovery_and_development_of_cyclooxygenase_2_inhibitors wikiPageWikiLink Active_site.
• Discovery_and_development_of_cyclooxygenase_2_inhibitors wikiPageWikiLink Albumin.
• Discovery_and_development_of_cyclooxygenase_2_inhibitors wikiPageWikiLink Analgesic.
• Discovery_and_development_of_cyclooxygenase_2_inhibitors wikiPageWikiLink Arachidonic_acid.
• Discovery_and_development_of_cyclooxygenase_2_inhibitors wikiPageWikiLink Arginine.
• Discovery_and_development_of_cyclooxygenase_2_inhibitors wikiPageWikiLink Aromaticity.
• Discovery_and_development_of_cyclooxygenase_2_inhibitors wikiPageWikiLink Arthropathy.
• Discovery_and_development_of_cyclooxygenase_2_inhibitors wikiPageWikiLink Binding_site.
• Discovery_and_development_of_cyclooxygenase_2_inhibitors wikiPageWikiLink COX-2_inhibitor.
• Discovery_and_development_of_cyclooxygenase_2_inhibitors wikiPageWikiLink COX-3.
• Discovery_and_development_of_cyclooxygenase_2_inhibitors wikiPageWikiLink CYP3A4.
• Discovery_and_development_of_cyclooxygenase_2_inhibitors wikiPageWikiLink Category:COX-2_inhibitors.
• Discovery_and_development_of_cyclooxygenase_2_inhibitors wikiPageWikiLink Category:Drug_discovery.
• Discovery_and_development_of_cyclooxygenase_2_inhibitors wikiPageWikiLink Celecoxib.
• Discovery_and_development_of_cyclooxygenase_2_inhibitors wikiPageWikiLink Chemical_affinity.
• Discovery_and_development_of_cyclooxygenase_2_inhibitors wikiPageWikiLink Chemical_polarity.
• Discovery_and_development_of_cyclooxygenase_2_inhibitors wikiPageWikiLink Concept_testing.
• Discovery_and_development_of_cyclooxygenase_2_inhibitors wikiPageWikiLink Cyclooxygenase.
• Discovery_and_development_of_cyclooxygenase_2_inhibitors wikiPageWikiLink Cytochrome_P450.
• Discovery_and_development_of_cyclooxygenase_2_inhibitors wikiPageWikiLink Downregulation_and_upregulation.
• Discovery_and_development_of_cyclooxygenase_2_inhibitors wikiPageWikiLink Endothelium.
• Discovery_and_development_of_cyclooxygenase_2_inhibitors wikiPageWikiLink Enzyme_inhibitor.
• Discovery_and_development_of_cyclooxygenase_2_inhibitors wikiPageWikiLink Etoricoxib.
• Discovery_and_development_of_cyclooxygenase_2_inhibitors wikiPageWikiLink Fibroblast.
• Discovery_and_development_of_cyclooxygenase_2_inhibitors wikiPageWikiLink First_pass_effect.
• Discovery_and_development_of_cyclooxygenase_2_inhibitors wikiPageWikiLink Gastrointestinal_tract.
• Discovery_and_development_of_cyclooxygenase_2_inhibitors wikiPageWikiLink Glucuronide.
• Discovery_and_development_of_cyclooxygenase_2_inhibitors wikiPageWikiLink Glutamine.
• Discovery_and_development_of_cyclooxygenase_2_inhibitors wikiPageWikiLink Half-life.
• Discovery_and_development_of_cyclooxygenase_2_inhibitors wikiPageWikiLink Histidine.
• Discovery_and_development_of_cyclooxygenase_2_inhibitors wikiPageWikiLink Hydrogen_bond.
• Discovery_and_development_of_cyclooxygenase_2_inhibitors wikiPageWikiLink Hydrolysis.
• Discovery_and_development_of_cyclooxygenase_2_inhibitors wikiPageWikiLink Hydrophile.
• Discovery_and_development_of_cyclooxygenase_2_inhibitors wikiPageWikiLink Hydrophobe.
• Discovery_and_development_of_cyclooxygenase_2_inhibitors wikiPageWikiLink Hyperalgesia.
• Discovery_and_development_of_cyclooxygenase_2_inhibitors wikiPageWikiLink Indometacin.
• Discovery_and_development_of_cyclooxygenase_2_inhibitors wikiPageWikiLink Integral.
• Discovery_and_development_of_cyclooxygenase_2_inhibitors wikiPageWikiLink Isoleucine.
• Discovery_and_development_of_cyclooxygenase_2_inhibitors wikiPageWikiLink Leucine.
• Discovery_and_development_of_cyclooxygenase_2_inhibitors wikiPageWikiLink Lipophilicity.
• Discovery_and_development_of_cyclooxygenase_2_inhibitors wikiPageWikiLink Lumiracoxib.
• Discovery_and_development_of_cyclooxygenase_2_inhibitors wikiPageWikiLink Messenger_RNA.
• Discovery_and_development_of_cyclooxygenase_2_inhibitors wikiPageWikiLink Metabolism.
• Discovery_and_development_of_cyclooxygenase_2_inhibitors wikiPageWikiLink Myocardial_infarction.
• Discovery_and_development_of_cyclooxygenase_2_inhibitors wikiPageWikiLink NS-398.
• Discovery_and_development_of_cyclooxygenase_2_inhibitors wikiPageWikiLink Naproxen.
• Discovery_and_development_of_cyclooxygenase_2_inhibitors wikiPageWikiLink Nitric_oxide.
• Discovery_and_development_of_cyclooxygenase_2_inhibitors wikiPageWikiLink Nitric_oxide_synthase.
• Discovery_and_development_of_cyclooxygenase_2_inhibitors wikiPageWikiLink Nitrite.
• Discovery_and_development_of_cyclooxygenase_2_inhibitors wikiPageWikiLink Nonsteroidal_anti-inflammatory_drug.
• Discovery_and_development_of_cyclooxygenase_2_inhibitors wikiPageWikiLink Osteoarthritis.
• Discovery_and_development_of_cyclooxygenase_2_inhibitors wikiPageWikiLink Oxidative_stress.
• Discovery_and_development_of_cyclooxygenase_2_inhibitors wikiPageWikiLink PTGS1.
• Discovery_and_development_of_cyclooxygenase_2_inhibitors wikiPageWikiLink Parecoxib.
• Discovery_and_development_of_cyclooxygenase_2_inhibitors wikiPageWikiLink Peroxide.
• Discovery_and_development_of_cyclooxygenase_2_inhibitors wikiPageWikiLink Peroxynitrite.
• Discovery_and_development_of_cyclooxygenase_2_inhibitors wikiPageWikiLink Pharmacodynamics.
• Discovery_and_development_of_cyclooxygenase_2_inhibitors wikiPageWikiLink Pharmacokinetics.
• Discovery_and_development_of_cyclooxygenase_2_inhibitors wikiPageWikiLink Phenyl_group.
• Discovery_and_development_of_cyclooxygenase_2_inhibitors wikiPageWikiLink Phenylalanine.
• Discovery_and_development_of_cyclooxygenase_2_inhibitors wikiPageWikiLink Polyunsaturated_fat.
• Discovery_and_development_of_cyclooxygenase_2_inhibitors wikiPageWikiLink Potency_(pharmacology).
• Discovery_and_development_of_cyclooxygenase_2_inhibitors wikiPageWikiLink Prodrug.
• Discovery_and_development_of_cyclooxygenase_2_inhibitors wikiPageWikiLink Prostacyclin.
• Discovery_and_development_of_cyclooxygenase_2_inhibitors wikiPageWikiLink Prostaglandin.
• Discovery_and_development_of_cyclooxygenase_2_inhibitors wikiPageWikiLink Prostaglandin-endoperoxide_synthase_2.
• Discovery_and_development_of_cyclooxygenase_2_inhibitors wikiPageWikiLink Prostaglandin_H2.
• Discovery_and_development_of_cyclooxygenase_2_inhibitors wikiPageWikiLink Prostanoid.
• Discovery_and_development_of_cyclooxygenase_2_inhibitors wikiPageWikiLink Protein_dimer.
• Discovery_and_development_of_cyclooxygenase_2_inhibitors wikiPageWikiLink Redox.
• Discovery_and_development_of_cyclooxygenase_2_inhibitors wikiPageWikiLink Rheumatism.
• Discovery_and_development_of_cyclooxygenase_2_inhibitors wikiPageWikiLink Rofecoxib.
• Discovery_and_development_of_cyclooxygenase_2_inhibitors wikiPageWikiLink Spontaneously_hypertensive_rat.
• Discovery_and_development_of_cyclooxygenase_2_inhibitors wikiPageWikiLink Steric_effects.
• Discovery_and_development_of_cyclooxygenase_2_inhibitors wikiPageWikiLink Stilbene.
• Discovery_and_development_of_cyclooxygenase_2_inhibitors wikiPageWikiLink Sulfide.
• Discovery_and_development_of_cyclooxygenase_2_inhibitors wikiPageWikiLink Sulfonamide.
• Discovery_and_development_of_cyclooxygenase_2_inhibitors wikiPageWikiLink Sulfone.
• Discovery_and_development_of_cyclooxygenase_2_inhibitors wikiPageWikiLink Sulfoxide.
• Discovery_and_development_of_cyclooxygenase_2_inhibitors wikiPageWikiLink Superoxide.
• Discovery_and_development_of_cyclooxygenase_2_inhibitors wikiPageWikiLink Synovial_fluid.
• Discovery_and_development_of_cyclooxygenase_2_inhibitors wikiPageWikiLink Tetrahydrobiopterin.
• Discovery_and_development_of_cyclooxygenase_2_inhibitors wikiPageWikiLink Thromboxane.
• Discovery_and_development_of_cyclooxygenase_2_inhibitors wikiPageWikiLink Tyrosine.
• Discovery_and_development_of_cyclooxygenase_2_inhibitors wikiPageWikiLink Valdecoxib.
• Discovery_and_development_of_cyclooxygenase_2_inhibitors wikiPageWikiLink Valine.
• Discovery_and_development_of_cyclooxygenase_2_inhibitors wikiPageWikiLink File:COXII-receptor.png.
• Discovery_and_development_of_cyclooxygenase_2_inhibitors wikiPageWikiLink File:Celecoxib_structure.png.
• Discovery_and_development_of_cyclooxygenase_2_inhibitors wikiPageWikiLink File:DuP-697.png.
• Discovery_and_development_of_cyclooxygenase_2_inhibitors wikiPageWikiLink File:Etoricoxib.svg.
• Discovery_and_development_of_cyclooxygenase_2_inhibitors wikiPageWikiLink File:Lumiracoxib.svg.
• Discovery_and_development_of_cyclooxygenase_2_inhibitors wikiPageWikiLink File:Parecoxib.svg.
• Discovery_and_development_of_cyclooxygenase_2_inhibitors wikiPageWikiLink File:Rofecoxib_skeletal.png.

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