Matches in DBpedia 2016-04 for { <http://dbpedia.org/resource/Diprenorphine> ?p ?o }
- Diprenorphine abstract "Diprenorphine (diprenorfin, Revivon, M5050) is an non-selective opioid antagonist, though it may have some slight partial agonist activity at the kappa-opioid receptor. It is used to reverse the effects of super-potent opioid analgesics such as etorphine and carfentanil that are used for tranquilizing large animals in veterinary medicine.Diprenorphine is the strongest opiate antagonist that is commercially available (some 100 times more potent as an antagonist than nalorphine), and is used for reversing the effects of very strong opioids for which the binding affinity is so high that naloxone does not effectively or reliably reverse the narcotic effects. These super-potent opioids, with the single exception of buprenorphine (which has an improved safety-profile due to its partial agonism character), are not used in humans because the dose for a human is so small that it would be difficult to measure properly, so there is an excessive risk of overdose leading to fatal respiratory depression. However conventional opioid derivatives are not strong enough to rapidly tranquilize large animals such as elephants and rhinos, so drugs such as etorphine or carfentanil are available for this purpose.Diprenorphine is considered the specific antagonist for etorphine and carfentanil, and is normally used to remobilise animals once veterinary procedures have been completed. Because diprenorphine also has some agonistic properties of its own, it should not be used on humans in the event that they are accidentally exposed to etorphine or carfentanil. Naloxone or naltrexone are the preferred human antagonists.In theory, diprenorphine could also be used as an antidote for treating overdose of certain opioid derivatives which are used in humans, such as buprenorphine (which has an improved safety-profile due to its partial agonism character), for which the binding affinity is so high that naloxone does not reliably reverse the narcotic effects. However, diprenorphine is not generally available in hospitals; instead a vial of diprenorphine is supplied with etorphine or carfentanil specifically for reversing the effects of these drugs, so use of diprenorphine for treating e.g. a buprenorphine overdose is not usually carried out in practice.".
- Diprenorphine atcPrefix "V03".
- Diprenorphine atcSuffix "AB92".
- Diprenorphine casNumber "14357-78-9".
- Diprenorphine drugbank "DB01548".
- Diprenorphine fdaUniiCode "1F0L5N25ZZ".
- Diprenorphine iupacName "(5α,7α)-17-(Cyclopropylmethyl)- 4,5-epoxy- 18,19-dihydro- 3-hydroxy- 6-methoxy- α,α-dimethyl- 6,14-ethenomorphinan- 7-methanol".
- Diprenorphine pubchem "443408".
- Diprenorphine thumbnail Diprenorphine.svg?width=300.
- Diprenorphine wikiPageID "10977211".
- Diprenorphine wikiPageLength "6595".
- Diprenorphine wikiPageOutDegree "20".
- Diprenorphine wikiPageRevisionID "702377420".
- Diprenorphine wikiPageWikiLink Analgesic.
- Diprenorphine wikiPageWikiLink Buprenorphine.
- Diprenorphine wikiPageWikiLink Carfentanil.
- Diprenorphine wikiPageWikiLink Category:Alcohols.
- Diprenorphine wikiPageWikiLink Category:Ethers.
- Diprenorphine wikiPageWikiLink Category:Kappa_antagonists.
- Diprenorphine wikiPageWikiLink Category:Morphinans.
- Diprenorphine wikiPageWikiLink Category:Opioid_antagonists.
- Diprenorphine wikiPageWikiLink Category:Phenols.
- Diprenorphine wikiPageWikiLink Category:Semisynthetic_opioids.
- Diprenorphine wikiPageWikiLink Drug_overdose.
- Diprenorphine wikiPageWikiLink Etorphine.
- Diprenorphine wikiPageWikiLink Hypoventilation.
- Diprenorphine wikiPageWikiLink Nalorphine.
- Diprenorphine wikiPageWikiLink Naloxone.
- Diprenorphine wikiPageWikiLink Opioid_antagonist.
- Diprenorphine wikiPageWikiLink Partial_agonist.
- Diprenorphine wikiPageWikiLink Veterinary_medicine.
- Diprenorphine wikiPageWikiLink Κ-opioid_receptor.
- Diprenorphine wikiPageWikiLinkText "Diprenorphine".
- Diprenorphine wikiPageWikiLinkText "diprenorphine".
- Diprenorphine atcPrefix "V03".
- Diprenorphine atcSuffix "AB92".
- Diprenorphine atcvet "yes".
- Diprenorphine c "26".
- Diprenorphine casNumber "14357".
- Diprenorphine chembl "281786".
- Diprenorphine chemspiderid "391634".
- Diprenorphine drugbank "DB01548".
- Diprenorphine h "35".
- Diprenorphine inchi "1".
- Diprenorphine inchikey "OIJXLIIMXHRJJH-KNLIIKEYBV".
- Diprenorphine iupacName "-17".
- Diprenorphine iupharLigand "1617".
- Diprenorphine kegg "D07863".
- Diprenorphine molecularWeight "425.56".
- Diprenorphine n "1".
- Diprenorphine o "4".
- Diprenorphine pubchem "443408".
- Diprenorphine smiles "CCO".
- Diprenorphine stdinchi "1".
- Diprenorphine stdinchikey "OIJXLIIMXHRJJH-KNLIIKEYSA-N".
- Diprenorphine unii "1".
- Diprenorphine verifiedfields "changed".
- Diprenorphine verifiedrevid "460793422".
- Diprenorphine width "180".
- Diprenorphine wikiPageUsesTemplate Template:Cascite.
- Diprenorphine wikiPageUsesTemplate Template:Chemspidercite.
- Diprenorphine wikiPageUsesTemplate Template:Drugbankcite.
- Diprenorphine wikiPageUsesTemplate Template:Drugbox.
- Diprenorphine wikiPageUsesTemplate Template:Drugs.com.
- Diprenorphine wikiPageUsesTemplate Template:Ebicite.
- Diprenorphine wikiPageUsesTemplate Template:Fdacite.
- Diprenorphine wikiPageUsesTemplate Template:Keggcite.
- Diprenorphine wikiPageUsesTemplate Template:Opioidergics.
- Diprenorphine wikiPageUsesTemplate Template:Reflist.
- Diprenorphine wikiPageUsesTemplate Template:Stdinchicite.
- Diprenorphine subject Category:Alcohols.
- Diprenorphine subject Category:Ethers.
- Diprenorphine subject Category:Kappa_antagonists.
- Diprenorphine subject Category:Morphinans.
- Diprenorphine subject Category:Opioid_antagonists.
- Diprenorphine subject Category:Phenols.
- Diprenorphine subject Category:Semisynthetic_opioids.
- Diprenorphine hypernym Antagonist.
- Diprenorphine type ChemicalSubstance.
- Diprenorphine type Drug.
- Diprenorphine type Group.
- Diprenorphine type Alcohol.
- Diprenorphine type Antagonist.
- Diprenorphine type Chemical.
- Diprenorphine type Ether.
- Diprenorphine type Group.
- Diprenorphine type Heterocycle.
- Diprenorphine type Opioid.
- Diprenorphine type Redirect.
- Diprenorphine type ChemicalObject.
- Diprenorphine type Thing.
- Diprenorphine type Q8386.
- Diprenorphine comment "Diprenorphine (diprenorfin, Revivon, M5050) is an non-selective opioid antagonist, though it may have some slight partial agonist activity at the kappa-opioid receptor.".
- Diprenorphine label "Diprenorphine".
- Diprenorphine sameAs Q424009.
- Diprenorphine sameAs Diprenorphin.
- Diprenorphine sameAs Diprenorfiini.
- Diprenorphine sameAs m.02qwy_c.
- Diprenorphine sameAs Diprenorfin.
- Diprenorphine sameAs Diprenorfin.