Matches in DBpedia 2016-04 for { <http://dbpedia.org/resource/DUSP12> ?p ?o }
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- DUSP12 abstract "Dual specificity protein phosphatase 12 is an enzyme that in humans is encoded by the DUSP12 gene.The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which is associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product is the human ortholog of the Saccharomyces cerevisiae YVH1 protein tyrosine phosphatase. It is localized predominantly in the nucleus, and is novel in that it contains, and is regulated by a zinc finger domain.".
- DUSP12 entrezgene "11266".
- DUSP12 wikiPageID "16860020".
- DUSP12 wikiPageLength "4437".
- DUSP12 wikiPageOutDegree "2".
- DUSP12 wikiPageRevisionID "661002260".
- DUSP12 wikiPageWikiLink Enzyme.
- DUSP12 wikiPageWikiLink Gene.
- DUSP12 wikiPageWikiLinkText "DUSP12".
- DUSP12 requireManualInspection "no".
- DUSP12 summaryText "The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein kinase superfamily , which is associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product is the human ortholog of the Saccharomyces cerevisiae YVH1 protein tyrosine phosphatase. It is localized predominantly in the nucleus, and is novel in that it contains, and is regulated by a zinc finger domain.".
- DUSP12 updateCitations "yes".
- DUSP12 updatePage "yes".
- DUSP12 updateProteinBox "yes".
- DUSP12 updateSummary "yes".
- DUSP12 wikiPageUsesTemplate Template:Cite_journal.
- DUSP12 wikiPageUsesTemplate Template:Gene-1-stub.
- DUSP12 wikiPageUsesTemplate Template:PBB.
- DUSP12 wikiPageUsesTemplate Template:PBB_Controls.
- DUSP12 wikiPageUsesTemplate Template:PBB_Further_reading.
- DUSP12 wikiPageUsesTemplate Template:PBB_Summary.
- DUSP12 wikiPageUsesTemplate Template:Protein_tyrosine_phosphatases.
- DUSP12 wikiPageUsesTemplate Template:Refbegin.
- DUSP12 wikiPageUsesTemplate Template:Refend.
- DUSP12 wikiPageUsesTemplate Template:Reflist.
- DUSP12 hypernym Enzyme.
- DUSP12 type Biomolecule.
- DUSP12 type Protein.
- DUSP12 type Thing.
- DUSP12 type Q206229.
- DUSP12 type Q8054.
- DUSP12 comment "Dual specificity protein phosphatase 12 is an enzyme that in humans is encoded by the DUSP12 gene.The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues.".
- DUSP12 label "DUSP12".
- DUSP12 sameAs Q18036443.
- DUSP12 sameAs m.0408r0q.
- DUSP12 sameAs Q18036443.
- DUSP12 wasDerivedFrom DUSP12?oldid=661002260.
- DUSP12 isPrimaryTopicOf DUSP12.