Matches in DBpedia 2016-04 for { <http://dbpedia.org/resource/DFFB> ?p ?o }
Showing triples 1 to 52 of
52
with 100 triples per page.
- DFFB abstract "DNA fragmentation factor subunit beta is a protein that in humans is encoded by the DFFB gene.Apoptosis is a cell death process that removes toxic and/or useless cells during mammalian development. The apoptotic process is accompanied by shrinkage and fragmentation of the cells and nuclei and degradation of the chromosomal DNA into nucleosomal units. DNA fragmentation factor (DFF) is a heterodimeric protein of 40-kD (DFFB) and 45-kD (DFFA) subunits. DFFA is the substrate for caspase-3 and triggers DNA fragmentation during apoptosis. DFF becomes activated when DFFA is cleaved by caspase-3. The cleaved fragments of DFFA dissociate from DFFB, the active component of DFF. DFFB has been found to trigger both DNA fragmentation and chromatin condensation during apoptosis. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene, but the biological validity of some variants has not been determined.".
- DFFB entrezgene "1677".
- DFFB symbol "DFF40".
- DFFB thumbnail PDB_1v0d_EBI.jpg?width=300.
- DFFB wikiPageID "14755493".
- DFFB wikiPageLength "10659".
- DFFB wikiPageOutDegree "5".
- DFFB wikiPageRevisionID "678276706".
- DFFB wikiPageWikiLink DFFA.
- DFFB wikiPageWikiLink Gene.
- DFFB wikiPageWikiLink Protein.
- DFFB wikiPageWikiLink Protein–protein_interaction.
- DFFB wikiPageWikiLinkText "DFFB".
- DFFB caption "crystal structure of caspase-activated dnase".
- DFFB interpro "IPR015311".
- DFFB name "DNA fragmentation factor 40 kDa".
- DFFB pfam "PF09230".
- DFFB requireManualInspection "no".
- DFFB scop "0.0".
- DFFB summaryText "Apoptosis is a cell death process that removes toxic and/or useless cells during mammalian development. The apoptotic process is accompanied by shrinkage and fragmentation of the cells and nuclei and degradation of the chromosomal DNA into nucleosomal units. DNA fragmentation factor is a heterodimeric protein of 40-kD and 45-kD subunits. DFFA is the substrate for caspase-3 and triggers DNA fragmentation during apoptosis. DFF becomes activated when DFFA is cleaved by caspase-3. The cleaved fragments of DFFA dissociate from DFFB, the active component of DFF. DFFB has been found to trigger both DNA fragmentation and chromatin condensation during apoptosis. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene, but the biological validity of some variants has not been determined.".
- DFFB symbol "DFF40".
- DFFB updateCitations "yes".
- DFFB updatePage "yes".
- DFFB updateProteinBox "yes".
- DFFB updateSummary "yes".
- DFFB wikiPageUsesTemplate Template:Cite_journal.
- DFFB wikiPageUsesTemplate Template:Gene-1-stub.
- DFFB wikiPageUsesTemplate Template:Infobox_protein_family.
- DFFB wikiPageUsesTemplate Template:Merge.
- DFFB wikiPageUsesTemplate Template:PBB.
- DFFB wikiPageUsesTemplate Template:PBB_Controls.
- DFFB wikiPageUsesTemplate Template:PBB_Further_reading.
- DFFB wikiPageUsesTemplate Template:PBB_Summary.
- DFFB wikiPageUsesTemplate Template:PDB_Gallery.
- DFFB wikiPageUsesTemplate Template:Refbegin.
- DFFB wikiPageUsesTemplate Template:Refend.
- DFFB wikiPageUsesTemplate Template:Reflist.
- DFFB hypernym Protein.
- DFFB type Biomolecule.
- DFFB type Protein.
- DFFB type Chemical.
- DFFB type Thing.
- DFFB type Q206229.
- DFFB type Q8054.
- DFFB comment "DNA fragmentation factor subunit beta is a protein that in humans is encoded by the DFFB gene.Apoptosis is a cell death process that removes toxic and/or useless cells during mammalian development. The apoptotic process is accompanied by shrinkage and fragmentation of the cells and nuclei and degradation of the chromosomal DNA into nucleosomal units. DNA fragmentation factor (DFF) is a heterodimeric protein of 40-kD (DFFB) and 45-kD (DFFA) subunits.".
- DFFB label "DFFB".
- DFFB sameAs Q17913960.
- DFFB sameAs m.03gwt5q.
- DFFB sameAs Q17913960.
- DFFB wasDerivedFrom DFFB?oldid=678276706.
- DFFB depiction PDB_1v0d_EBI.jpg.
- DFFB isPrimaryTopicOf DFFB.
