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- Cometabolism abstract "Co-metabolism is defined as the simultaneous degradation of two compounds, in which the degradation of the second compound (the secondary substrate) depends on the presence of the first compound (the primary substrate). For example, in the process of metabolizing methane, propane or simple sugars, some bacteria, such as Pseudomonas stutzeri OX1, can degrade hazardous chlorinated solvents, such as tetrachloroethylene and trichloroethylene, that they would otherwise be unable to attack. They do this by producing methane monooxygenase, an enzyme which is known to oxidize numerous compounds, including pollutants such as chlorinated solvents, via co-metabolism. Co-metabolism is thus used as an approach to biological degradation of hazardous solvents. Another example is Mycobacterium vaccae, which uses an enzyme to oxidize propane. Accidentally, this enzyme also oxidizes, at no additional cost for M. vaccae, cyclohexane into cyclohexanol. Thus, cyclohexane is co-metabolized in the presence of propane. This allows for the commensal growth of Pseudomonas on cyclohexane. The latter can metabolize cyclohexanol, but not cyclohexane.Another promising method of bioremediation of chlorinated solvents involves co-metabolismof the contaminants by aerobic microorganisms in groundwater and soils. Severalaerobic microorganisms have been demonstrated to be capable of doing this, including methaneoxidizers, phenol-degraders, and toluene-degraders. Unlike reductivedechlorination, the chlorinated compounds are completely mineralized to CO2 and chloride withno intermediates making co-metabolism an attractive alternative where it can be sustained.However, the microorganisms gain no energy from these processes, limiting the ability of cells toco-metabolize chlorinated compounds. This, together with the difficulties and highcosts of maintaining substrate and an oxic environment, have led to limited field-scaleapplication of co-metabolism for solvent degradation".
- Cometabolism wikiPageID "2999211".
- Cometabolism wikiPageLength "2912".
- Cometabolism wikiPageOutDegree "18".
- Cometabolism wikiPageRevisionID "686692683".
- Cometabolism wikiPageWikiLink Biodegradation.
- Cometabolism wikiPageWikiLink Category:Biomechanics.
- Cometabolism wikiPageWikiLink Chemical_compound.
- Cometabolism wikiPageWikiLink Chemical_decomposition.
- Cometabolism wikiPageWikiLink Cyclohexane.
- Cometabolism wikiPageWikiLink Cyclohexanol.
- Cometabolism wikiPageWikiLink Enzyme.
- Cometabolism wikiPageWikiLink Halogenation.
- Cometabolism wikiPageWikiLink Hazard.
- Cometabolism wikiPageWikiLink Methane.
- Cometabolism wikiPageWikiLink Methane_monooxygenase.
- Cometabolism wikiPageWikiLink Mycobacterium_vaccae.
- Cometabolism wikiPageWikiLink Propane.
- Cometabolism wikiPageWikiLink Pseudomonas.
- Cometabolism wikiPageWikiLink Solvent.
- Cometabolism wikiPageWikiLink Substrate_(chemistry).
- Cometabolism wikiPageWikiLink Tetrachloroethylene.
- Cometabolism wikiPageWikiLink Trichloroethylene.
- Cometabolism wikiPageWikiLinkText "Cometabolism".
- Cometabolism wikiPageWikiLinkText "co-metabolically".
- Cometabolism wikiPageWikiLinkText "cometabolism".
- Cometabolism wikiPageUsesTemplate Template:Biochem-stub.
- Cometabolism wikiPageUsesTemplate Template:Refimprove.
- Cometabolism subject Category:Biomechanics.
- Cometabolism type Biophysic.
- Cometabolism type Mechanic.
- Cometabolism comment "Co-metabolism is defined as the simultaneous degradation of two compounds, in which the degradation of the second compound (the secondary substrate) depends on the presence of the first compound (the primary substrate). For example, in the process of metabolizing methane, propane or simple sugars, some bacteria, such as Pseudomonas stutzeri OX1, can degrade hazardous chlorinated solvents, such as tetrachloroethylene and trichloroethylene, that they would otherwise be unable to attack.".
- Cometabolism label "Cometabolism".
- Cometabolism sameAs Q908975.
- Cometabolism sameAs Cometabolismus.
- Cometabolism sameAs Kometabolism.
- Cometabolism sameAs m.08jpjn.
- Cometabolism sameAs Q908975.
- Cometabolism wasDerivedFrom Cometabolism?oldid=686692683.
- Cometabolism isPrimaryTopicOf Cometabolism.