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- Chemical_specificity abstract "Chemical specificity is the ability of a protein's binding site to bind specific ligands. The fewer ligands a protein can bind, the greater its specificity.Specificity has its technical basis as an experimental measurement in enzyme kinetics, where the strength of binding between a given protein and ligand can be described by a dissociation constant, which characterizes the balance between bound and unbound states for the protein-ligand system. In the context of a single enzyme and a pair of binding molecules, the two ligands can be compared as stronger or weaker ligands (for the enzyme) on the basis of their dissociation constants. (A lower value corresponds to a stronger binding.)Specificity for a set of ligands is unrelated to the ability of an enzyme to catalyze a given reaction, with the ligand as a substrate.If a given enzyme has a high chemical specificity, this means that the set of ligands to which it binds is limited, such that neither binding events nor catalysis can occur at an appreciable rate with additional molecules.An example of a protein-ligand pair whose binding activity can be described as highly specific is the antibody-antigen system. Conversely, an example of a protein-ligand system that can bind substrates and catalyze multiple reactions effectively is the Cytochrome P450 system, which can be considered a promiscuous enzyme due to its broad specificity for multiple ligands.".
- Chemical_specificity wikiPageID "529609".
- Chemical_specificity wikiPageLength "1701".
- Chemical_specificity wikiPageOutDegree "14".
- Chemical_specificity wikiPageRevisionID "560314756".
- Chemical_specificity wikiPageWikiLink Antibody.
- Chemical_specificity wikiPageWikiLink Antigen.
- Chemical_specificity wikiPageWikiLink Binding_site.
- Chemical_specificity wikiPageWikiLink Catalysis.
- Chemical_specificity wikiPageWikiLink Category:Chemical_bonding.
- Chemical_specificity wikiPageWikiLink Category:Proteins.
- Chemical_specificity wikiPageWikiLink Chemical_affinity.
- Chemical_specificity wikiPageWikiLink Cytochrome_P450.
- Chemical_specificity wikiPageWikiLink Dissociation_constant.
- Chemical_specificity wikiPageWikiLink Enzyme.
- Chemical_specificity wikiPageWikiLink Enzyme_kinetics.
- Chemical_specificity wikiPageWikiLink Enzyme_promiscuity.
- Chemical_specificity wikiPageWikiLink Ligand_(biochemistry).
- Chemical_specificity wikiPageWikiLink Protein.
- Chemical_specificity wikiPageWikiLinkText "chemical specificity".
- Chemical_specificity wikiPageWikiLinkText "specificity".
- Chemical_specificity wikiPageUsesTemplate Template:Biochem-stub.
- Chemical_specificity wikiPageUsesTemplate Template:Unreferenced.
- Chemical_specificity subject Category:Chemical_bonding.
- Chemical_specificity subject Category:Proteins.
- Chemical_specificity hypernym Ability.
- Chemical_specificity type Biomolecule.
- Chemical_specificity type Disease.
- Chemical_specificity type Biomolecule.
- Chemical_specificity type Nutrient.
- Chemical_specificity comment "Chemical specificity is the ability of a protein's binding site to bind specific ligands. The fewer ligands a protein can bind, the greater its specificity.Specificity has its technical basis as an experimental measurement in enzyme kinetics, where the strength of binding between a given protein and ligand can be described by a dissociation constant, which characterizes the balance between bound and unbound states for the protein-ligand system.".
- Chemical_specificity label "Chemical specificity".
- Chemical_specificity sameAs Q5090496.
- Chemical_specificity sameAs Especificitat_química.
- Chemical_specificity sameAs m.02m0bs.
- Chemical_specificity sameAs Q5090496.
- Chemical_specificity wasDerivedFrom Chemical_specificity?oldid=560314756.
- Chemical_specificity isPrimaryTopicOf Chemical_specificity.