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- Carpaine abstract "Carpaine is one of the major alkaloid components of papaya leaves which has been studied for its cardiovascular effects. Circulatory effects of carpaine were studied in Wistar male rats weighing 314 +/- 13 g, under pentobarbital (30 mg/kg) anesthesia. Increasing dosages of carpaine from 0.5 mg/kg to 2.0 mg/kg resulted in progressive decrease in systolic, diastolic, and mean arterial blood pressure. Selective autonomic nervous blockade with atropine sulfate (1 mg/kg) or propranolol hydrochloride (8 mg/kg) did not alter the circulatory response to carpaine. Carpaine, 2 mg/kg, reduced cardiac output, stroke volume, stroke work, and cardiac power, but the calculated total peripheral resistance remained unchanged. It is concluded from these results that carpaine affects the myocardium directly. The effects of carpaine may be related to its macrocyclic dilactone structure, a possible cation chelating structure.".
- Carpaine iupacName "(1S,11R,13S,14S,24R,26S)-13,26-Dimethyl-2,15-dioxa-".
- Carpaine iupacName "12,25-diazatricyclo[22.2.2.211,14]triacontane-3,16-dione".
- Carpaine thumbnail Carpaine.png?width=300.
- Carpaine wikiPageID "7949613".
- Carpaine wikiPageLength "3093".
- Carpaine wikiPageOutDegree "14".
- Carpaine wikiPageRevisionID "690946720".
- Carpaine wikiPageWikiLink Alkaloid.
- Carpaine wikiPageWikiLink Atropine.
- Carpaine wikiPageWikiLink Category:Alkaloids.
- Carpaine wikiPageWikiLink Category:Lactones.
- Carpaine wikiPageWikiLink Category:Macrocycles.
- Carpaine wikiPageWikiLink Category:Piperidines.
- Carpaine wikiPageWikiLink Chelation.
- Carpaine wikiPageWikiLink Circulatory_system.
- Carpaine wikiPageWikiLink Ion.
- Carpaine wikiPageWikiLink Lactone.
- Carpaine wikiPageWikiLink Macrocycle.
- Carpaine wikiPageWikiLink Papaya.
- Carpaine wikiPageWikiLink Pentobarbital.
- Carpaine wikiPageWikiLink Propranolol.
- Carpaine wikiPageWikiLinkText "Carpaine".
- Carpaine imagealt "Ball-and-stick model of the carpaine molecule".
- Carpaine imagealt "Skeletal formula of carpaine".
- Carpaine imagefile "Carpaine 3D ball.png".
- Carpaine imagefile "Carpaine.png".
- Carpaine iupacname "-1326".
- Carpaine iupacname "1225".
- Carpaine name "Carpaine".
- Carpaine othernames "-Carpaine".
- Carpaine verifiedfields "changed".
- Carpaine verifiedrevid "399708506".
- Carpaine wikiPageUsesTemplate Template:Cascite.
- Carpaine wikiPageUsesTemplate Template:Chembox.
- Carpaine wikiPageUsesTemplate Template:Chembox_Identifiers.
- Carpaine wikiPageUsesTemplate Template:Chembox_Properties.
- Carpaine wikiPageUsesTemplate Template:Chemspidercite.
- Carpaine wikiPageUsesTemplate Template:Ebicite.
- Carpaine wikiPageUsesTemplate Template:Heterocyclic-stub.
- Carpaine wikiPageUsesTemplate Template:Stdinchicite.
- Carpaine subject Category:Alkaloids.
- Carpaine subject Category:Lactones.
- Carpaine subject Category:Macrocycles.
- Carpaine subject Category:Piperidines.
- Carpaine hypernym Components.
- Carpaine type Biomolecule.
- Carpaine type ChemicalCompound.
- Carpaine type ChemicalSubstance.
- Carpaine type Organisation.
- Carpaine type Alkaloid.
- Carpaine type Biomolecule.
- Carpaine type Ester.
- Carpaine type Heterocycle.
- Carpaine type Lactone.
- Carpaine type Macrocycle.
- Carpaine type Redirect.
- Carpaine type ChemicalObject.
- Carpaine type Thing.
- Carpaine type Q11173.
- Carpaine comment "Carpaine is one of the major alkaloid components of papaya leaves which has been studied for its cardiovascular effects. Circulatory effects of carpaine were studied in Wistar male rats weighing 314 +/- 13 g, under pentobarbital (30 mg/kg) anesthesia. Increasing dosages of carpaine from 0.5 mg/kg to 2.0 mg/kg resulted in progressive decrease in systolic, diastolic, and mean arterial blood pressure.".
- Carpaine label "Carpaine".
- Carpaine sameAs Q3179543.
- Carpaine sameAs Carpaína.
- Carpaine sameAs کارپین.
- Carpaine sameAs m.026l435.
- Carpaine sameAs Karpain.
- Carpaine sameAs Karpain.
- Carpaine sameAs Q3179543.
- Carpaine wasDerivedFrom Carpaine?oldid=690946720.
- Carpaine depiction Carpaine.png.
- Carpaine isPrimaryTopicOf Carpaine.
- Carpaine name "Carpaine".