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- Candidate_gene abstract "The candidate gene approach to conducting genetic association studies focuses on associations between genetic variation within pre-specified genes of interest and phenotypes or disease states. This is in contrast to genome-wide association studies (GWAS), which scan the entire genome for common genetic variation. Candidate genes are most often selected for study based on a priori knowledge of the gene’s biological functional impact on the trait or disease in question. The rationale behind focusing on allelic variation in specific, biologically relevant regions of the genome is that certain mutations will directly impact the function of the gene in question, and lead to the phenotype or disease state being investigated. This approach usually uses the case-control study design to try to answer the question, “Is one allele of a candidate gene more frequently seen in subjects with the disease than in subjects without the disease?”".
- Candidate_gene wikiPageExternalLink geneontology.org.
- Candidate_gene wikiPageExternalLink gene.
- Candidate_gene wikiPageExternalLink toppgene.cchmc.org.
- Candidate_gene wikiPageID "1795200".
- Candidate_gene wikiPageLength "13312".
- Candidate_gene wikiPageOutDegree "13".
- Candidate_gene wikiPageRevisionID "702094016".
- Candidate_gene wikiPageWikiLink Case-control_study.
- Candidate_gene wikiPageWikiLink Category:Genetics.
- Candidate_gene wikiPageWikiLink Comparative_genomics.
- Candidate_gene wikiPageWikiLink Expressivity_(genetics).
- Candidate_gene wikiPageWikiLink Genetic_association.
- Candidate_gene wikiPageWikiLink Genome-wide_association_study.
- Candidate_gene wikiPageWikiLink Microarray.
- Candidate_gene wikiPageWikiLink Penetrance.
- Candidate_gene wikiPageWikiLink Population_stratification.
- Candidate_gene wikiPageWikiLink Quantitative_trait_locus.
- Candidate_gene wikiPageWikiLinkText "Candidate gene".
- Candidate_gene wikiPageWikiLinkText "candidate gene".
- Candidate_gene wikiPageWikiLinkText "candidate genes".
- Candidate_gene wikiPageWikiLinkText "candidate region".
- Candidate_gene wikiPageWikiLinkText "candidates".
- Candidate_gene wikiPageWikiLinkText "gene candidates".
- Candidate_gene wikiPageWikiLinkText "gene-specific candidate-driven studies".
- Candidate_gene wikiPageUsesTemplate Template:Qg.
- Candidate_gene subject Category:Genetics.
- Candidate_gene type Redirect.
- Candidate_gene comment "The candidate gene approach to conducting genetic association studies focuses on associations between genetic variation within pre-specified genes of interest and phenotypes or disease states. This is in contrast to genome-wide association studies (GWAS), which scan the entire genome for common genetic variation. Candidate genes are most often selected for study based on a priori knowledge of the gene’s biological functional impact on the trait or disease in question.".
- Candidate_gene label "Candidate gene".
- Candidate_gene sameAs Q1423575.
- Candidate_gene sameAs Kandidatengen.
- Candidate_gene sameAs ژن_نامزد.
- Candidate_gene sameAs Kandidaatgen.
- Candidate_gene sameAs m.05xmdp.
- Candidate_gene sameAs Ген-кандидат.
- Candidate_gene sameAs Q1423575.
- Candidate_gene wasDerivedFrom Candidate_gene?oldid=702094016.
- Candidate_gene isPrimaryTopicOf Candidate_gene.