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- CID-85469571 abstract "CID-85469571 is a compound which acts as an antagonist at the former orphan receptor GPR18, and is the first selective antagonist characterised for this receptor, with an IC50 of 279nM, and good selectivity over related receptors (over 36x selectivity vs CB1 and GPR55, and 14x vs CB2.) As all previously known antagonists for GPR18 also antagonise GPR55, it has been difficult to separate the effects of these two receptor targets, so the discovery of a selective GPR18 antagonist is expected to be useful in research into the actions of this receptor.".
- CID-85469571 iupacName "(2Z)-2-[(3-[(4-chlorophenyl)methoxy]phenyl)methylidene]-6,7-dihydro-5H-imidazo[2,1-b][1,3]thiazin-3-one".
- CID-85469571 pubchem "85469571".
- CID-85469571 thumbnail CID85469571_structure.png?width=300.
- CID-85469571 wikiPageID "44530148".
- CID-85469571 wikiPageLength "1869".
- CID-85469571 wikiPageOutDegree "9".
- CID-85469571 wikiPageRevisionID "705278507".
- CID-85469571 wikiPageWikiLink CID-16020046.
- CID-85469571 wikiPageWikiLink Cannabinoid_receptor_type_1.
- CID-85469571 wikiPageWikiLink Cannabinoid_receptor_type_2.
- CID-85469571 wikiPageWikiLink Category:Cannabinoids.
- CID-85469571 wikiPageWikiLink GPR18.
- CID-85469571 wikiPageWikiLink GPR55.
- CID-85469571 wikiPageWikiLink O-1918.
- CID-85469571 wikiPageWikiLink Orphan_receptor.
- CID-85469571 wikiPageWikiLink Receptor_antagonist.
- CID-85469571 wikiPageWikiLinkText "CID-85469571".
- CID-85469571 c "20".
- CID-85469571 chemspiderid "34226942".
- CID-85469571 cl "1".
- CID-85469571 h "17".
- CID-85469571 inchi "1".
- CID-85469571 inchikey "XJBQRMOGMULGPP-PDGQHHTCBE".
- CID-85469571 iupacName "-2".
- CID-85469571 molecularWeight "384.879".
- CID-85469571 n "2".
- CID-85469571 o "2".
- CID-85469571 pubchem "85469571".
- CID-85469571 s "1".
- CID-85469571 smiles "Clc4cccCOccccc2\C=C/N=C3N1CCCS3".
- CID-85469571 stdinchi "1".
- CID-85469571 stdinchikey "XJBQRMOGMULGPP-PDGQHHTCSA-N".
- CID-85469571 width "200".
- CID-85469571 wikiPageUsesTemplate Template:Cannabinoidergics.
- CID-85469571 wikiPageUsesTemplate Template:Cannabinoids.
- CID-85469571 wikiPageUsesTemplate Template:Drugbox.
- CID-85469571 wikiPageUsesTemplate Template:Reflist.
- CID-85469571 subject Category:Cannabinoids.
- CID-85469571 hypernym Compound.
- CID-85469571 type ChemicalCompound.
- CID-85469571 type ChemicalSubstance.
- CID-85469571 type Drug.
- CID-85469571 type ChemicalObject.
- CID-85469571 type Thing.
- CID-85469571 type Q8386.
- CID-85469571 comment "CID-85469571 is a compound which acts as an antagonist at the former orphan receptor GPR18, and is the first selective antagonist characterised for this receptor, with an IC50 of 279nM, and good selectivity over related receptors (over 36x selectivity vs CB1 and GPR55, and 14x vs CB2.) As all previously known antagonists for GPR18 also antagonise GPR55, it has been difficult to separate the effects of these two receptor targets, so the discovery of a selective GPR18 antagonist is expected to be useful in research into the actions of this receptor.".
- CID-85469571 label "CID-85469571".
- CID-85469571 sameAs Q19903835.
- CID-85469571 sameAs m.012ccm09.
- CID-85469571 sameAs Q19903835.
- CID-85469571 wasDerivedFrom CID-85469571?oldid=705278507.
- CID-85469571 depiction CID85469571_structure.png.
- CID-85469571 isPrimaryTopicOf CID-85469571.