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- Aptiganel abstract "Aptiganel (Cerestat; CNS-1102) was a drug candidate that acted as a noncompetitive NMDA antagonist and that was under development by Cambridge Neuroscience, Inc as a treatment for stroke. It has neuroprotective effects and was researched for potential use in the treatment of stroke, but despite positive results in animal studies, human trials showed limited efficacy, as well as undesirable side effects such as sedation and hallucinations, and clinical development was ultimately not continued.The drug's failure led to the collapse of Cambridge Neuroscience in 1998 and its eventually sale to CeNeS Pharmaceuticals in 2000.".
- Aptiganel atcPrefix "none".
- Aptiganel casNumber "137159-92-3".
- Aptiganel fdaUniiCode "46475LV84I".
- Aptiganel iupacName "1-(3-ethylphenyl)-1-methyl-2-naphthalen-1-ylguanidine".
- Aptiganel pubchem "60840".
- Aptiganel thumbnail Aptiganel.svg?width=300.
- Aptiganel wikiPageID "18485979".
- Aptiganel wikiPageLength "5145".
- Aptiganel wikiPageOutDegree "13".
- Aptiganel wikiPageRevisionID "691002897".
- Aptiganel wikiPageWikiLink 1-Naphthylamine.
- Aptiganel wikiPageWikiLink Category:Anilines.
- Aptiganel wikiPageWikiLink Category:Guanidines.
- Aptiganel wikiPageWikiLink Category:NMDA_receptor_antagonists.
- Aptiganel wikiPageWikiLink Category:Naphthylamines.
- Aptiganel wikiPageWikiLink Cyanogen_bromide.
- Aptiganel wikiPageWikiLink Ditolylguanidine.
- Aptiganel wikiPageWikiLink Hallucination.
- Aptiganel wikiPageWikiLink NMDA_receptor_antagonist.
- Aptiganel wikiPageWikiLink Neuroprotection.
- Aptiganel wikiPageWikiLink Sedation.
- Aptiganel wikiPageWikiLink Stroke.
- Aptiganel wikiPageWikiLink File:Aptiganel_synthesis.svg.
- Aptiganel wikiPageWikiLinkText "Aptiganel".
- Aptiganel wikiPageWikiLinkText "aptiganel".
- Aptiganel atcPrefix "none".
- Aptiganel c "20".
- Aptiganel casNumber "137159".
- Aptiganel chembl "92484".
- Aptiganel chemspiderid "54827".
- Aptiganel h "21".
- Aptiganel inchi "1".
- Aptiganel inchikey "BFNCJMURTMZBTE-UHFFFAOYAY".
- Aptiganel iupacName "1".
- Aptiganel legalStatus "Uncontrolled".
- Aptiganel molecularWeight "303.401".
- Aptiganel n "3".
- Aptiganel pubchem "60840".
- Aptiganel smiles "CCC1=CCNCN".
- Aptiganel stdinchi "1".
- Aptiganel stdinchikey "BFNCJMURTMZBTE-UHFFFAOYSA-N".
- Aptiganel unii "46475".
- Aptiganel verifiedfields "changed".
- Aptiganel verifiedrevid "477350281".
- Aptiganel wikiPageUsesTemplate Template:Cascite.
- Aptiganel wikiPageUsesTemplate Template:Chemspidercite.
- Aptiganel wikiPageUsesTemplate Template:Drugbox.
- Aptiganel wikiPageUsesTemplate Template:Ebicite.
- Aptiganel wikiPageUsesTemplate Template:Fdacite.
- Aptiganel wikiPageUsesTemplate Template:Glutamatergics.
- Aptiganel wikiPageUsesTemplate Template:Hallucinogens.
- Aptiganel wikiPageUsesTemplate Template:Reflist.
- Aptiganel wikiPageUsesTemplate Template:Stdinchicite.
- Aptiganel subject Category:Anilines.
- Aptiganel subject Category:Guanidines.
- Aptiganel subject Category:NMDA_receptor_antagonists.
- Aptiganel subject Category:Naphthylamines.
- Aptiganel hypernym Candidate.
- Aptiganel type ChemicalSubstance.
- Aptiganel type Drug.
- Aptiganel type Person.
- Aptiganel type Antagonist.
- Aptiganel type Chemical.
- Aptiganel type Drug.
- Aptiganel type Enamine.
- Aptiganel type Redirect.
- Aptiganel type ChemicalObject.
- Aptiganel type Thing.
- Aptiganel type Q8386.
- Aptiganel comment "Aptiganel (Cerestat; CNS-1102) was a drug candidate that acted as a noncompetitive NMDA antagonist and that was under development by Cambridge Neuroscience, Inc as a treatment for stroke.".
- Aptiganel label "Aptiganel".
- Aptiganel sameAs Q4782250.
- Aptiganel sameAs m.04f34rd.
- Aptiganel sameAs Aptiganel.
- Aptiganel sameAs Aptiganel.
- Aptiganel sameAs Q4782250.
- Aptiganel wasDerivedFrom Aptiganel?oldid=691002897.
- Aptiganel depiction Aptiganel.svg.
- Aptiganel isPrimaryTopicOf Aptiganel.