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- Amiflamine abstract "Amiflamine (FLA-336) is a reversible inhibitor of monoamine oxidase A (MAO-A), thereby being a RIMA, and, to a lesser extent, semicarbazide-sensitive amine oxidase (SSAO), as well as a serotonin releasing agent (SRA). It is a derivative of the phenethylamine and amphetamine chemical classes. The (+)-enantiomer is the active stereoisomer.Amiflamine is unique among MAOIs in that it shows preference for inhibiting MAO-A in serotonergic relative to noradrenergic and dopaminergic neurons. In other words, at low doses, it can be used to selectively inhibit MAO-A enzymes in serotonin cells, whereas at higher doses it loses its selectivity. This property is attributed to amiflamine's higher affinity for the serotonin transporter over the norepinephrine and dopamine transporters, as transporter-mediated carriage is required for amiflamine to enter monoaminergic neurons.".
- Amiflamine atcPrefix "none".
- Amiflamine casNumber "77518-07-1".
- Amiflamine fdaUniiCode "NE25WV9C8S".
- Amiflamine iupacName "4-[(2S)-2-aminopropyl]-N,N,3-trimethylaniline".
- Amiflamine pubchem "71221".
- Amiflamine thumbnail Amiflamine.svg?width=300.
- Amiflamine wikiPageID "26338492".
- Amiflamine wikiPageLength "5235".
- Amiflamine wikiPageOutDegree "25".
- Amiflamine wikiPageRevisionID "669682176".
- Amiflamine wikiPageWikiLink Category:Anilines.
- Amiflamine wikiPageWikiLink Category:Monoamine_oxidase_inhibitors.
- Amiflamine wikiPageWikiLink Category:Phenethylamines.
- Amiflamine wikiPageWikiLink Category:Serotonin_releasing_agents.
- Amiflamine wikiPageWikiLink Chemical_classification.
- Amiflamine wikiPageWikiLink Derivative_(chemistry).
- Amiflamine wikiPageWikiLink Dopamine_transporter.
- Amiflamine wikiPageWikiLink Dopaminergic.
- Amiflamine wikiPageWikiLink Enantiomer.
- Amiflamine wikiPageWikiLink Enzyme_inhibitor.
- Amiflamine wikiPageWikiLink Ligand_(biochemistry).
- Amiflamine wikiPageWikiLink Monoamine_oxidase_A.
- Amiflamine wikiPageWikiLink Monoamine_oxidase_inhibitor.
- Amiflamine wikiPageWikiLink Neuron.
- Amiflamine wikiPageWikiLink Norepinephrine.
- Amiflamine wikiPageWikiLink Norepinephrine_transporter.
- Amiflamine wikiPageWikiLink Primary-amine_oxidase.
- Amiflamine wikiPageWikiLink Reversible_inhibitor_of_monoamine_oxidase_A.
- Amiflamine wikiPageWikiLink Serotonergic.
- Amiflamine wikiPageWikiLink Serotonin_releasing_agent.
- Amiflamine wikiPageWikiLink Serotonin_transporter.
- Amiflamine wikiPageWikiLink Stereoisomerism.
- Amiflamine wikiPageWikiLink Substituted_amphetamine.
- Amiflamine wikiPageWikiLink Substituted_phenethylamine.
- Amiflamine wikiPageWikiLinkText "Amiflamine".
- Amiflamine wikiPageWikiLinkText "amiflamine".
- Amiflamine atcPrefix "none".
- Amiflamine c "12".
- Amiflamine casNumber "77518".
- Amiflamine chembl "30344".
- Amiflamine chemspiderid "64356".
- Amiflamine h "20".
- Amiflamine inchi "1".
- Amiflamine inchikey "HFQMYSHATTXRTC-JTQLQIEIBH".
- Amiflamine iupacName "4".
- Amiflamine legalStatus "Uncontrolled".
- Amiflamine molecularWeight "192.3".
- Amiflamine n "2".
- Amiflamine pubchem "71221".
- Amiflamine routesOfAdministration "Oral".
- Amiflamine smiles "NC".
- Amiflamine stdinchi "1".
- Amiflamine stdinchikey "HFQMYSHATTXRTC-JTQLQIEISA-N".
- Amiflamine synonyms "-4".
- Amiflamine unii "NE25WV9C8S".
- Amiflamine verifiedfields "changed".
- Amiflamine verifiedrevid "454124445".
- Amiflamine width "175".
- Amiflamine wikiPageUsesTemplate Template:Adrenergics.
- Amiflamine wikiPageUsesTemplate Template:Cascite.
- Amiflamine wikiPageUsesTemplate Template:Chemspidercite.
- Amiflamine wikiPageUsesTemplate Template:Drugbox.
- Amiflamine wikiPageUsesTemplate Template:Ebicite.
- Amiflamine wikiPageUsesTemplate Template:Fdacite.
- Amiflamine wikiPageUsesTemplate Template:Phenethylamines.
- Amiflamine wikiPageUsesTemplate Template:Reflist.
- Amiflamine wikiPageUsesTemplate Template:Stdinchicite.
- Amiflamine subject Category:Anilines.
- Amiflamine subject Category:Monoamine_oxidase_inhibitors.
- Amiflamine subject Category:Phenethylamines.
- Amiflamine subject Category:Serotonin_releasing_agents.
- Amiflamine hypernym Inhibitor.
- Amiflamine type ChemicalSubstance.
- Amiflamine type Drug.
- Amiflamine type Drug.
- Amiflamine type Enamine.
- Amiflamine type ChemicalObject.
- Amiflamine type Thing.
- Amiflamine type Q8386.
- Amiflamine comment "Amiflamine (FLA-336) is a reversible inhibitor of monoamine oxidase A (MAO-A), thereby being a RIMA, and, to a lesser extent, semicarbazide-sensitive amine oxidase (SSAO), as well as a serotonin releasing agent (SRA). It is a derivative of the phenethylamine and amphetamine chemical classes. The (+)-enantiomer is the active stereoisomer.Amiflamine is unique among MAOIs in that it shows preference for inhibiting MAO-A in serotonergic relative to noradrenergic and dopaminergic neurons.".
- Amiflamine label "Amiflamine".
- Amiflamine sameAs Q4746184.
- Amiflamine sameAs m.0bbyrd8.
- Amiflamine sameAs Amiflamin.
- Amiflamine sameAs Amiflamin.
- Amiflamine sameAs Q4746184.
- Amiflamine wasDerivedFrom Amiflamine?oldid=669682176.
- Amiflamine depiction Amiflamine.svg.
- Amiflamine isPrimaryTopicOf Amiflamine.