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- Addiction-related_structural_neuroplasticity abstract "Addiction is a state characterized by compulsive engagement in rewarding stimuli, despite adverse consequences. The process of developing an addiction occurs through instrumental learning, which is otherwise known as operant conditioning.In humans, addiction is diagnosed according to diagnostic models such as the Diagnostic and Statistical Manual of Mental Disorders, through observed behaviors. There has been significant advancement in understanding the structural changes that occur in parts of the brain involved in the reward pathway (mesolimbic system) that underlies addiction. Most research has focused on two portions of the brain: the ventral tegmental area, (VTA) and the nucleus accumbens (NAc).The VTA is the portion of the mesolimbic system responsible for spreading dopamine to the whole system. The VTA is stimulated by ″rewarding experiences″. The release of dopamine by the VTA induces pleasure, thus reinforcing behaviors that lead to the reward. Drugs of abuse increase the VTA’s ability to project dopamine to the rest of the reward circuit. These structural changes only last 7–10 days, however, indicating that the VTA cannot be the only part of the brain that is affected by drug use, and changed during the development of addiction.The nucleus accumbens (NAc) plays an essential part in the formation of addiction. Almost every drug with addictive potential induces the release of dopamine into the NAc. In contrast to the VTA, the NAc shows long-term structural changes. Drugs of abuse weaken the connections within the NAc after habitual use, as well as after use then withdrawal.".
- Addiction-related_structural_neuroplasticity wikiPageID "37691875".
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- Addiction-related_structural_neuroplasticity wikiPageRevisionID "704351466".
- Addiction-related_structural_neuroplasticity wikiPageWikiLink AMPA_receptor.
- Addiction-related_structural_neuroplasticity wikiPageWikiLink Addiction.
- Addiction-related_structural_neuroplasticity wikiPageWikiLink Amygdala.
- Addiction-related_structural_neuroplasticity wikiPageWikiLink Category:Addiction.
- Addiction-related_structural_neuroplasticity wikiPageWikiLink Dextromethorphan.
- Addiction-related_structural_neuroplasticity wikiPageWikiLink Diagnostic_and_Statistical_Manual_of_Mental_Disorders.
- Addiction-related_structural_neuroplasticity wikiPageWikiLink Dopamine.
- Addiction-related_structural_neuroplasticity wikiPageWikiLink Dopaminergic.
- Addiction-related_structural_neuroplasticity wikiPageWikiLink Dysphoria.
- Addiction-related_structural_neuroplasticity wikiPageWikiLink Gamma-Aminobutyric_acid.
- Addiction-related_structural_neuroplasticity wikiPageWikiLink Hippocampus.
- Addiction-related_structural_neuroplasticity wikiPageWikiLink Interneuron.
- Addiction-related_structural_neuroplasticity wikiPageWikiLink Ketamine.
- Addiction-related_structural_neuroplasticity wikiPageWikiLink Limbic_system.
- Addiction-related_structural_neuroplasticity wikiPageWikiLink Long-term_depression.
- Addiction-related_structural_neuroplasticity wikiPageWikiLink Long-term_potentiation.
- Addiction-related_structural_neuroplasticity wikiPageWikiLink Mesolimbic_pathway.
- Addiction-related_structural_neuroplasticity wikiPageWikiLink NMDA_receptor.
- Addiction-related_structural_neuroplasticity wikiPageWikiLink NMDA_receptor_antagonist.
- Addiction-related_structural_neuroplasticity wikiPageWikiLink Neurotransmitter.
- Addiction-related_structural_neuroplasticity wikiPageWikiLink Nucleus_accumbens.
- Addiction-related_structural_neuroplasticity wikiPageWikiLink Operant_conditioning.
- Addiction-related_structural_neuroplasticity wikiPageWikiLink Opioid.
- Addiction-related_structural_neuroplasticity wikiPageWikiLink Phencyclidine.
- Addiction-related_structural_neuroplasticity wikiPageWikiLink Phenotype.
- Addiction-related_structural_neuroplasticity wikiPageWikiLink Prefrontal_cortex.
- Addiction-related_structural_neuroplasticity wikiPageWikiLink Relapse.
- Addiction-related_structural_neuroplasticity wikiPageWikiLink Reuptake.
- Addiction-related_structural_neuroplasticity wikiPageWikiLink Signal_transduction.
- Addiction-related_structural_neuroplasticity wikiPageWikiLink Stimulant.
- Addiction-related_structural_neuroplasticity wikiPageWikiLink Striatum.
- Addiction-related_structural_neuroplasticity wikiPageWikiLink Ventral_tegmental_area.
- Addiction-related_structural_neuroplasticity wikiPageWikiLinkText "Addiction-related structural neuroplasticity".
- Addiction-related_structural_neuroplasticity colwidth "20".
- Addiction-related_structural_neuroplasticity part "yes".
- Addiction-related_structural_neuroplasticity source "FOSB".
- Addiction-related_structural_neuroplasticity wikiPageUsesTemplate Template:Citation_needed.
- Addiction-related_structural_neuroplasticity wikiPageUsesTemplate Template:Main.
- Addiction-related_structural_neuroplasticity wikiPageUsesTemplate Template:Medref.
- Addiction-related_structural_neuroplasticity wikiPageUsesTemplate Template:Multiple_issues.
- Addiction-related_structural_neuroplasticity wikiPageUsesTemplate Template:Orphan.
- Addiction-related_structural_neuroplasticity wikiPageUsesTemplate Template:Reflist.
- Addiction-related_structural_neuroplasticity wikiPageUsesTemplate Template:Speculation_inline.
- Addiction-related_structural_neuroplasticity wikiPageUsesTemplate Template:Transcluded-section.
- Addiction-related_structural_neuroplasticity subject Category:Addiction.
- Addiction-related_structural_neuroplasticity hypernym State.
- Addiction-related_structural_neuroplasticity type PopulatedPlace.
- Addiction-related_structural_neuroplasticity comment "Addiction is a state characterized by compulsive engagement in rewarding stimuli, despite adverse consequences. The process of developing an addiction occurs through instrumental learning, which is otherwise known as operant conditioning.In humans, addiction is diagnosed according to diagnostic models such as the Diagnostic and Statistical Manual of Mental Disorders, through observed behaviors.".
- Addiction-related_structural_neuroplasticity label "Addiction-related structural neuroplasticity".
- Addiction-related_structural_neuroplasticity sameAs Q7625015.
- Addiction-related_structural_neuroplasticity sameAs m.0ndxhtg.
- Addiction-related_structural_neuroplasticity sameAs Q7625015.
- Addiction-related_structural_neuroplasticity wasDerivedFrom Addiction-related_structural_neuroplasticity?oldid=704351466.
- Addiction-related_structural_neuroplasticity isPrimaryTopicOf Addiction-related_structural_neuroplasticity.