Matches in DBpedia 2016-04 for { <http://dbpedia.org/resource/6-APDB> ?p ?o }
- 6-APDB abstract "6-(2-Aminopropyl)-2,3-dihydrobenzofuran (6-APDB, 4-Desoxy-MDA, EMA-3) is a stimulant and entactogen drug of the phenethylamine and amphetamine classes. It is an analogue of MDA where the heterocyclic 4-position oxygen from the 3,4-methylenedioxy ring has been replaced with a methylene bridge. 5-APDB (3-Desoxy-MDA) is an analogue of 6-APDB where the 3-position oxygen has been replaced with a methylene instead. 6-APDB, along with 5-APDB, was first synthesized by David E. Nichols in the early 1990s while investigating non-neurotoxic MDMA analogues.In animal studies, 6-APDB fully substitutes for MBDB and MMAI but not for amphetamine or LSD. In vitro, 6-APDB has been shown to inhibit the reuptake of serotonin, dopamine, and norepinephrine with IC50 values of 322 nM, 1,997 nM, and 980 nM, respectively. These values are very similar to those of MDA, but with those for the catecholamines slightly lower in comparison, perhaps more similarly to MDMA. In contrast, 5-APDB is highly selective for serotonin. Though 6-APDB does not substitute for amphetamine in rats at the doses used in referenced study, based on its in vitro profile it can be suggested that it may have amphetamine-like effects at higher doses.The unsaturated benzofuran derivative 6-APB, or 6-(2-aminopropyl)benzofuran is also known, but the difference in pharmacological effects between 6-APB and 6-APDB is unclear.6-APDB is a class B drug in the UK since June 10, 2013. It is banned by a blanket law on benzofurans and related compounds.".
- 6-APDB atcPrefix "none".
- 6-APDB casNumber "152623-93-3".
- 6-APDB iupacName "1-(2,3-dihydro-1-benzofuran-6-yl)propan-2-amine".
- 6-APDB pubchem "192599".
- 6-APDB thumbnail 4-desoxy-MDA.svg?width=300.
- 6-APDB wikiPageID "26886441".
- 6-APDB wikiPageLength "4628".
- 6-APDB wikiPageOutDegree "44".
- 6-APDB wikiPageRevisionID "699233493".
- 6-APDB wikiPageWikiLink 1,3-Benzodioxolyl-N-methylbutanamine.
- 6-APDB wikiPageWikiLink 5-APB.
- 6-APDB wikiPageWikiLink 5-APDB.
- 6-APDB wikiPageWikiLink 5-APDI.
- 6-APDB wikiPageWikiLink 5-IT.
- 6-APDB wikiPageWikiLink 6-APB.
- 6-APDB wikiPageWikiLink 6-APT.
- 6-APDB wikiPageWikiLink Amphetamine.
- 6-APDB wikiPageWikiLink Catecholamine.
- 6-APDB wikiPageWikiLink Category:Benzofurans.
- 6-APDB wikiPageWikiLink Category:Designer_drugs.
- 6-APDB wikiPageWikiLink Category:Entactogens_and_empathogens.
- 6-APDB wikiPageWikiLink Category:Serotonin-norepinephrine-dopamine_releasing_agents.
- 6-APDB wikiPageWikiLink Category:Substituted_amphetamines.
- 6-APDB wikiPageWikiLink David_E._Nichols.
- 6-APDB wikiPageWikiLink Dopamine.
- 6-APDB wikiPageWikiLink Drug.
- 6-APDB wikiPageWikiLink EDMA.
- 6-APDB wikiPageWikiLink Empathogen-entactogen.
- 6-APDB wikiPageWikiLink Functional_group.
- 6-APDB wikiPageWikiLink Heterocyclic_compound.
- 6-APDB wikiPageWikiLink IC50.
- 6-APDB wikiPageWikiLink In_vitro.
- 6-APDB wikiPageWikiLink Lysergic_acid_diethylamide.
- 6-APDB wikiPageWikiLink MDMA.
- 6-APDB wikiPageWikiLink MMAI.
- 6-APDB wikiPageWikiLink Methylene_bridge.
- 6-APDB wikiPageWikiLink Methylenedioxy.
- 6-APDB wikiPageWikiLink Methylenedioxyamphetamine.
- 6-APDB wikiPageWikiLink Naphthylaminopropane.
- 6-APDB wikiPageWikiLink Neurotoxicity.
- 6-APDB wikiPageWikiLink Norepinephrine.
- 6-APDB wikiPageWikiLink Organic_synthesis.
- 6-APDB wikiPageWikiLink Oxygen.
- 6-APDB wikiPageWikiLink Reuptake.
- 6-APDB wikiPageWikiLink Reuptake_inhibitor.
- 6-APDB wikiPageWikiLink Serotonin.
- 6-APDB wikiPageWikiLink Stimulant.
- 6-APDB wikiPageWikiLink Structural_analog.
- 6-APDB wikiPageWikiLink Substituted_amphetamine.
- 6-APDB wikiPageWikiLink Substituted_phenethylamine.
- 6-APDB wikiPageWikiLinkText "6-APDB".
- 6-APDB alt "Ball-and-stick model of the 6-APDB molecule".
- 6-APDB atcPrefix "none".
- 6-APDB c "11".
- 6-APDB casNumber "152623".
- 6-APDB chembl "124055".
- 6-APDB chemspiderid "167141".
- 6-APDB h "15".
- 6-APDB image "6".
- 6-APDB inchi "1".
- 6-APDB inchikey "VRNGXHJGMCJRSQ-UHFFFAOYAT".
- 6-APDB iupacName "1".
- 6-APDB legalUk "Class B".
- 6-APDB molecularWeight "177.24".
- 6-APDB n "1".
- 6-APDB o "1".
- 6-APDB pregnancyCategory "?".
- 6-APDB pubchem "192599".
- 6-APDB routesOfAdministration "Oral".
- 6-APDB smiles "O2c1ccCCC".
- 6-APDB stdinchi "1".
- 6-APDB stdinchikey "VRNGXHJGMCJRSQ-UHFFFAOYSA-N".
- 6-APDB verifiedfields "changed".
- 6-APDB verifiedrevid "477225590".
- 6-APDB wikiPageUsesTemplate Template:Cascite.
- 6-APDB wikiPageUsesTemplate Template:Chemspidercite.
- 6-APDB wikiPageUsesTemplate Template:Colbegin.
- 6-APDB wikiPageUsesTemplate Template:Colend.
- 6-APDB wikiPageUsesTemplate Template:Drugbox.
- 6-APDB wikiPageUsesTemplate Template:Ebicite.
- 6-APDB wikiPageUsesTemplate Template:Entactogens.
- 6-APDB wikiPageUsesTemplate Template:Phenethylamines.
- 6-APDB wikiPageUsesTemplate Template:Reflist.
- 6-APDB wikiPageUsesTemplate Template:Serotonergics.
- 6-APDB wikiPageUsesTemplate Template:Stdinchicite.
- 6-APDB subject Category:Benzofurans.
- 6-APDB subject Category:Designer_drugs.
- 6-APDB subject Category:Entactogens_and_empathogens.
- 6-APDB subject Category:Serotonin-norepinephrine-dopamine_releasing_agents.
- 6-APDB subject Category:Substituted_amphetamines.
- 6-APDB hypernym Stimulant.
- 6-APDB type ChemicalSubstance.
- 6-APDB type Drug.
- 6-APDB type Dissociative.
- 6-APDB type Drug.
- 6-APDB type Euphoriant.
- 6-APDB type Heterocycle.
- 6-APDB type Stimulant.
- 6-APDB type ChemicalObject.