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- 5-APB abstract "5-APB (5-(2-aminopropyl)benzofuran, 1-benzofuran-5-ylpropan-2-amine, benzofury) is a triple monoamine reuptake inhibitor with Ki values of 180, 265 and 811 nM for NET, DAT and SERT respectively as well as being a potent agonist for the 5-HT2A and 5-HT2B receptors (Ki of 14nM at 5-HT2B). This agonism for 5-HT2B makes it likely that 5-APB would be cardiotoxic with long term use, as seen in other 5-HT2B agonists such as fenfluramine and MDMA. The subjective effects and structure-activity relationship suggest that 5-APB is also a monoamine releasing agent.5-APB is commonly found as the succinate and hydrochloride salt. The hydrochloride salt is 10% more potent by mass and doses should be adjusted accordingly.5-APB is also an agonist of the 5-HT2C receptor as well as a triple monoamine reuptake inhibitor. It has been sold as a designer drug since 2010.".
- 5-APB atcPrefix "none".
- 5-APB casNumber "286834-81-9".
- 5-APB iupacName "5-(2-Aminopropyl)benzofuran".
- 5-APB pubchem "9837232".
- 5-APB thumbnail 5-APB2DACS.svg?width=300.
- 5-APB wikiPageID "31136906".
- 5-APB wikiPageLength "6097".
- 5-APB wikiPageOutDegree "31".
- 5-APB wikiPageRevisionID "685406138".
- 5-APB wikiPageWikiLink 5-APDB.
- 5-APB wikiPageWikiLink 5-APDI.
- 5-APB wikiPageWikiLink 5-EAPB.
- 5-APB wikiPageWikiLink 5-HT2A_receptor.
- 5-APB wikiPageWikiLink 5-HT2B_receptor.
- 5-APB wikiPageWikiLink 5-HT2C_receptor.
- 5-APB wikiPageWikiLink 5-IT.
- 5-APB wikiPageWikiLink 5-MAPB.
- 5-APB wikiPageWikiLink 5-MAPDB.
- 5-APB wikiPageWikiLink 6-APB.
- 5-APB wikiPageWikiLink 6-APDB.
- 5-APB wikiPageWikiLink 6-APT.
- 5-APB wikiPageWikiLink 6-EAPB.
- 5-APB wikiPageWikiLink 6-MAPB.
- 5-APB wikiPageWikiLink 6-MAPDB.
- 5-APB wikiPageWikiLink Agonist.
- 5-APB wikiPageWikiLink Category:Benzofurans.
- 5-APB wikiPageWikiLink Category:Designer_drugs.
- 5-APB wikiPageWikiLink Category:Serotonin-norepinephrine-dopamine_releasing_agents.
- 5-APB wikiPageWikiLink Category:Serotonin_receptor_agonists.
- 5-APB wikiPageWikiLink Category:Substituted_amphetamines.
- 5-APB wikiPageWikiLink Designer_drug.
- 5-APB wikiPageWikiLink Drug_Enforcement_Administration.
- 5-APB wikiPageWikiLink EDMA.
- 5-APB wikiPageWikiLink MDAI.
- 5-APB wikiPageWikiLink MMAI.
- 5-APB wikiPageWikiLink Naphthylaminopropane.
- 5-APB wikiPageWikiLink Serotonin–norepinephrine–dopamine_reuptake_inhibitor.
- 5-APB wikiPageWikiLink Structure–activity_relationship.
- 5-APB wikiPageWikiLink United_States_Department_of_Justice.
- 5-APB wikiPageWikiLinkText "5-APB".
- 5-APB alt "Ball-and-stick model of the 5-APB molecule".
- 5-APB atcPrefix "none".
- 5-APB c "11".
- 5-APB casNumber "286834".
- 5-APB chemspiderid "8012953".
- 5-APB h "13".
- 5-APB image "5".
- 5-APB inchi "1".
- 5-APB inchikey "VKUMKUZDZWHMQU-UHFFFAOYAQ".
- 5-APB iupacName "5".
- 5-APB legalDe "Anlage II".
- 5-APB legalUk "Class B".
- 5-APB molecularWeight "175.23".
- 5-APB n "1".
- 5-APB o "1".
- 5-APB pubchem "9837232".
- 5-APB smiles "CCCC1=CC=C2C=C1".
- 5-APB stdinchi "1".
- 5-APB stdinchikey "VKUMKUZDZWHMQU-UHFFFAOYSA-N".
- 5-APB synonyms "1".
- 5-APB synonyms "Benzo fury".
- 5-APB synonyms "Benzofury".
- 5-APB verifiedfields "changed".
- 5-APB verifiedrevid "458140931".
- 5-APB watchedfields "changed".
- 5-APB wikiPageUsesTemplate Template:Cascite.
- 5-APB wikiPageUsesTemplate Template:Chemspidercite.
- 5-APB wikiPageUsesTemplate Template:Citation_needed.
- 5-APB wikiPageUsesTemplate Template:Drugbox.
- 5-APB wikiPageUsesTemplate Template:Entactogens.
- 5-APB wikiPageUsesTemplate Template:Hallucinogens.
- 5-APB wikiPageUsesTemplate Template:Phenethylamines.
- 5-APB wikiPageUsesTemplate Template:Reflist.
- 5-APB wikiPageUsesTemplate Template:Serotonergics.
- 5-APB wikiPageUsesTemplate Template:Stdinchicite.
- 5-APB subject Category:Benzofurans.
- 5-APB subject Category:Designer_drugs.
- 5-APB subject Category:Serotonin-norepinephrine-dopamine_releasing_agents.
- 5-APB subject Category:Serotonin_receptor_agonists.
- 5-APB subject Category:Substituted_amphetamines.
- 5-APB hypernym Inhibitor.
- 5-APB type ChemicalSubstance.
- 5-APB type Drug.
- 5-APB type Chemical.
- 5-APB type Drug.
- 5-APB type Heterocycle.
- 5-APB type ChemicalObject.
- 5-APB type Thing.
- 5-APB type Q8386.
- 5-APB comment "5-APB (5-(2-aminopropyl)benzofuran, 1-benzofuran-5-ylpropan-2-amine, benzofury) is a triple monoamine reuptake inhibitor with Ki values of 180, 265 and 811 nM for NET, DAT and SERT respectively as well as being a potent agonist for the 5-HT2A and 5-HT2B receptors (Ki of 14nM at 5-HT2B). This agonism for 5-HT2B makes it likely that 5-APB would be cardiotoxic with long term use, as seen in other 5-HT2B agonists such as fenfluramine and MDMA.".
- 5-APB label "5-APB".
- 5-APB sameAs Q4639569.
- 5-APB sameAs m.0gh6_46.
- 5-APB sameAs 5-APB.
- 5-APB sameAs 5-APB.
- 5-APB sameAs Q4639569.
- 5-APB wasDerivedFrom 5-APB?oldid=685406138.
- 5-APB depiction 5-APB2DACS.svg.
- 5-APB isPrimaryTopicOf 5-APB.