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- Heterocodeine abstract "Heterocodeine (6-methoxymorphine) is an opiate derivative, the 6-methyl ether of morphine, and a structural isomer of codeine; it is called "hetero-" because it is the reverse isomer of codeine. Heterocodeine was first synthesised in 1932 and first patented in 1935. It can be made from morphine by selective methylation. Codeine is the natural mono-methyl ether, but must be metabolized for activity (that is, it is a prodrug). In contrast the semi-synthetic mono-methyl ether, heterocodeine is a direct agonist. The 3,6 methyl di-ether of morphine is thebaine.Heterocodeine is 6 times more potent than morphine due to having a substitution at the 6-hydroxy position, in a similar manner to 6-acetylmorphine. The drug methyldihydromorphine (dihydroheterocodeine) is a derivative of heterocodeine. Like the morphine metabolite morphine-6-glucuronide, 6-position branches (esters or ethers) of morphine bind to the otherwise unagonized human mu receptor subtype mu-3 (or μ3); as well as the 6-acetylmorphine metabolite of heroin this includes heterocodeine.The relative strength of heterocodeine to codeine has been published as 50, 72, 81, 88, 93, 96, and 108 x.It is not mentioned specifically in the Controlled Substances Act 1970 but is a Schedule II controlled substance as an analogue of morphinan or morphine under the morphine structure rules of the Analogues Act; in other countries it is usually controlled as a strong opioid.Homocodeine is a synonym for pholcodine.".
- Heterocodeine atcPrefix "none".
- Heterocodeine casNumber "639-47-4".
- Heterocodeine iupacName "(5α,6α)-6-Methoxy-17-methyl-7,8-didehydro-4,5-epoxymorphinan-3-ol".
- Heterocodeine pubchem "5462505".
- Heterocodeine thumbnail Heterocodeine.svg?width=300.
- Heterocodeine wikiPageID "13487160".
- Heterocodeine wikiPageRevisionID "618375366".
- Heterocodeine atcPrefix "none".
- Heterocodeine c "18".
- Heterocodeine casNumber "639".
- Heterocodeine chembl "358043".
- Heterocodeine chemspiderid "4575432".
- Heterocodeine h "21".
- Heterocodeine hasPhotoCollection Heterocodeine.
- Heterocodeine inchi "1".
- Heterocodeine inchikey "FNAHUZTWOVOCTL-XSSYPUMDBX".
- Heterocodeine iupacName "-6".
- Heterocodeine legalUs "CII".
- Heterocodeine molecularWeight "299.364".
- Heterocodeine n "1".
- Heterocodeine o "3".
- Heterocodeine pubchem "5462505".
- Heterocodeine smiles "O[C@H]2\C=C/[C@H]5[C@@H]4NC".
- Heterocodeine stdinchi "1".
- Heterocodeine stdinchikey "FNAHUZTWOVOCTL-XSSYPUMDSA-N".
- Heterocodeine synonyms "Heterocodeine, Morphine 6-methyl ether".
- Heterocodeine verifiedfields "changed".
- Heterocodeine verifiedrevid "461087666".
- Heterocodeine watchedfields "changed".
- Heterocodeine width "200".
- Heterocodeine subject Category:Ethers.
- Heterocodeine subject Category:Morphinans.
- Heterocodeine subject Category:Mu-opioid_agonists.
- Heterocodeine subject Category:Phenols.
- Heterocodeine subject Category:Semisynthetic_opioids.
- Heterocodeine type Abstraction100002137.
- Heterocodeine type Chemical114806838.
- Heterocodeine type Compound114818238.
- Heterocodeine type Element114840755.
- Heterocodeine type Ethers.
- Heterocodeine type Material114580897.
- Heterocodeine type Matter100020827.
- Heterocodeine type OrganicCompound114727670.
- Heterocodeine type Part113809207.
- Heterocodeine type Phenol114989545.
- Heterocodeine type Phenols.
- Heterocodeine type PhysicalEntity100001930.
- Heterocodeine type Quintessence114847103.
- Heterocodeine type Relation100031921.
- Heterocodeine type Substance100019613.
- Heterocodeine type Drug.
- Heterocodeine type DrugProduct.
- Heterocodeine type Thing.
- Heterocodeine type Q8386.
- Heterocodeine comment "Heterocodeine (6-methoxymorphine) is an opiate derivative, the 6-methyl ether of morphine, and a structural isomer of codeine; it is called "hetero-" because it is the reverse isomer of codeine. Heterocodeine was first synthesised in 1932 and first patented in 1935. It can be made from morphine by selective methylation. Codeine is the natural mono-methyl ether, but must be metabolized for activity (that is, it is a prodrug).".
- Heterocodeine label "Heterocodeine".
- Heterocodeine sameAs m.03c6z2x.
- Heterocodeine sameAs Q5746979.
- Heterocodeine sameAs Q5746979.
- Heterocodeine sameAs Heterocodeine.
- Heterocodeine wasDerivedFrom Heterocodeine?oldid=618375366.
- Heterocodeine depiction Heterocodeine.svg.
- Heterocodeine isPrimaryTopicOf Heterocodeine.